Women in Clinical Trials:
Lou Cantillina, MD: Terfenadine/Oral contraceptive study
David Flockhart, MD, PhD: Comparison of the beta-adrenergic antagonist actions of propranolol in men and women
Raymond L. Woosley, MD, PhD: Comparison of the potassium channel blocking actions of quinidine in men and women

Bruce V. Stadel, MD: Hormone replacement therapy in women with a previous diagnosis of endometrial cancer

Brenda Vaughan, MD: Thalidomide: Are there gender disparities in treatment outcome and non-teratogenic adverse effects?

Edwin J. Matthews, PhD: Estimation of reproductive toxicity of pharmaceuticals using QSAR software programs

Ellen R. Tabak, PhD: Gender differences in perception of risks communicated by prescription and over-the-counter drug labels, Phase I

Sheila Weiss, PhD: Profile of drug use in pregnancy

Ana Szarfman, MD, PhD: Visualization tools for studying gender differences

Ellen R. Tabak, PhD: Gender differences in perception of risks communicated by prescription and over-the-counter drug labels, Phase II

Ana Szarfman, MD, PhD, Raymond L. Woosley, MD, PhD: Variations in the drug-induced QT interval prolongation during the menstrual cycle (co-funded by NIH ORWH)

Shiew Mei Huang, PhD, Robert Branch, PhD: Gender differences in P450 activities and their implications (co-funded by NIH ORWH)

Carolyn McCloskey, M.D., MPH: Teratogen Surveillance

Thomas Layloff: Chemical characteristics of conjugated estrogens

John Strong, PhD: Contribution of estrogen components to the efficacy of conjugated estrogens-preliminary analytical chemistry (continuation of FY 97 project)

Kathryn Aiken, PhD: Pregnancy Labeling Taskforce: Focus Group testing (co-funded by NIH ORWH)

Ralph Lillie, RPh: Adverse Events Reporting System (AERS): Risk assessment, Compliance & Management

Ronald Honchel, Ph.D., Frank Sistare, Ph.D., "Evaluation of the Tg.AC transgenic mouse as a model for predicting the photocarcinogenicity of pharmaceuticals and cosmeceuticals"

Ann Farrell, M.D., Lilia Talarico, M.D., "Women's participation in clinical drug trials for unstable angina and myocardial infarction

OWH/CFSAN Funded Projects

John E. Bailey: AHA literature search

Sara B. Fein, PhD: Infant feeding practices study

Mary L. Tortorello, PhD: Rapid method for detection and enumeration of Listeria monocytogenes in foods

Ruth Welch: Osteoporosis prevention in adolescent girls

Ruth A. Welch, MS, RD: Women's health information line

Thomas J. Sobotka, PhD: Screening for nervous system dysfunction in offspring of dams exposed to natural food contaminates during pregnancy

Mona S. Calvo, PhD: Vitamin K status of non-Hispanic black and white girls and young adult women: Direct measure of serum phylloquinone levels and measurement of a new functional endpoint in serum samples from NHANES III

Shirley R. Blakely, PhD: Obesity: Its effect on antioxidant and estrogen metabolism

Nancy Slifman, MD, MPH: Contaminants in dietary supplements frequently used in women

Kenneth T. Durham: CFSAN's Internet initiative: infra-structure support

OWH/CVM Research Projects

OWH/NCTR Funded Projects

S. Jill James, PhD: Mechanism of immunotoxicity and carcinogenicity associated with silicone breast implants

Daniel M. Sheehan, PhD: Experimental assessment of environmental estrogens

Frederick A. Beland, PhD: DNA adducts of tamoxifen

S. Jill James, Ph.D.: Molecular and metabolic determinants of maternal risk and progression of Down's syndrome: Potential for nutritional intervention

William H. Tolleson, PhD: Development of in vitro human cell culture systems to screen compounds suspected to have estrogenic or anti-estrogen activity

Patricia Thompson, PhD: Part II of in-vivo modeling of steroid-mediated gender effects on cytochrome P450 3A4 and 2D6

Big Blue rats," Vasily Dobrolovsky, Ph.D., "Evaluation of the Tk knockout mouse as a model of systemic lupus erythematosus,"

CBER Funded Projects

Michael A. Norcross, MD: Women and AIDS transmission

David S. Finbloom, MD: Cytokine induced activation of the Jak kinase/STAT transcription factor pathway in immune cells (monocytes and lymphocytes) of patients with rheumatoid arthritis and systemic lupus erythematosus

Dennis Klinman, MD, PhD: Hormonal regulation of cytokine producing cells in women with systemic lupus erythematosus

Philip R. Krause, MD: Development of a method to evaluate the effect of vaccines and antiviral therapy on latent viral burden in an animal model of genital herpes

Dennis Klinman, MD, PhD: A novel approach to the treatment of lupus nephritis

Emily B. Shachter, PhD: Administration of thrombolytic therapy to women with acute myocardial infarction. Is it too late?

Giovanna Tosato, MD: IP-10: A potential new therapeutic for breast cancer

Penelope Robbins, PhD: Human cytotoxic T lymphocyte recognition of Papilloma virus

Margaret Bash, MD, MPH: Antigenic characteristics and immungenicity of synthetic peptide vaccines for the pathogenic Neisseria: Neisseria meningitides and Neisseria gonorrhea

Emily Shachter, PhD: Improve the efficacy of chemotherapeutic drugs for the treatment of breast cancer

Hana Golding, PhD: The role of HIV-1 co-receptors in sexual and mother-to-infant transmission

Frederick Miller, MD, PhD: Silicone gel-filled breast implant capsules: A molecular histologic and immunophenotypic study (continuation of FY 94 funding)

Vance Berger, PhD: Improving the evaluation of ovarian cancer treatment

Margaret Bash, MD, MPH: Antigenic characteristics and immungenicity of synthetic peptide vaccines for the pathogenic Neisseria: Neisseria meningitides and Neisseria gonorrhea (continuation of FY 98 award)

CDRH Funded Projects

Carol Sierka: Development of MQSA Speaker Kits

Langone/Jacobs: Silicone Gel Alternatives Workshop

K. Myers, PhD: Non-invasive assessment of silicone migration from gel-filled breast implants

Keith A. Wear, PhD: Application of ultrasonic tissue characterization to diagnosis of bone disease

Paula G. Silberberg, MD: Contraceptive efficacy table for uniform contraceptive labeling-- a consumer focus group study - Part I

Matthew R. Myers, PhD: A computer model for simulating virus transport through barriers

Paula Silberberg, MD: Reactions of women to contraceptive efficacy tables for uniform contraceptive labeling -- a consumer focus group study--Part II

Melvyn Greberman, MD, MPH: The transfer of defense, intelligence and space technologies for the early detection and control of cancers in women (conference)

S. Lori Brown, MD: Protocol for a study of breast implant rupture (co-funded by FDA-OC)

Robert Jennings, PhD: Optimization of mammography

Rosalie Bright, ScD: Mammography breast cancer screening rates among disadvantaged women within a pre-paid health care system

Danica Marinac-Dabic, MD: Gender differences in early and long-term results of coronary angioplasty with the Palmaz/Schatz stent

Steven Lascher, DVM, MPH: A comparison of gender specific utilization of implantable cardioverter defibrillator therapy and post-implantation survivability

Danica Marinac-Dabic, MD: Epidemiology of medical devices in women (conference)

Patricia Dubill, PhD: Abrasion testing of breast implants

James Karanian, PhD: Ovarian steroids and cardiovascular disease: the role of gender in the effectiveness of interventional medical devices

S. Lori Brown, M.D.: Protocol for a study of breast implant rupture (continuation from FY 97 funding)

Roselie Bright, ScD: Presentation of findings at the 14th International Conference on Pharmacoepidemiology (in conjunction with funded FY 97 project)

Danica Marinac-Dabic, MD: Conference on Epidemiology of medical devices in women

(publication of presentations from FY 97 project)

Harvey Rudolph, PhD: Accerlated aging studies of condoms/condom materials

Harvey Rudolph, PhD: Flow studies and the use of a waveguide in cardiovascular devices

Robert Navazio, Ph.D "Assessment of consumer understanding of barrier contraception and tampon labeling: Focus Group Studies"

Richard Kotz, Ph.D., CDRH, "A study to evaluate the consistency of T-scores among ultrasound bone measurement devices and the usefulness of these devices for monitoring bone status"