Occult Non-Small Cell Lung Cancer
Stage 0 (Carcinoma in Situ)
Stage I Non-Small Cell Lung Cancer
Stage II Non-Small Cell Lung Cancer
Stage IIIA and Stage IIIB Non-Small Cell Lung Cancer
Stage IV Non-Small Cell Lung Cancer

A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.

Treatment of occult non-small cell lung cancer depends on where the cancer has spread. It can usually be cured by surgery.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with occult non-small cell lung cancer.

Treatment of stage 0 may include the following:

• Surgery (wedge resection or segmental resection).
• Photodynamic therapy using an endoscope.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage 0 non-small cell lung cancer.

Treatment of stage I non-small cell lung cancer may include the following:

• Surgery (wedge resection, segmental resection, or lobectomy).
• External radiation therapy (for patients who cannot have surgery or choose not to have surgery).
• Surgery followed by chemotherapy.
• A clinical trial of photodynamic therapy using an endoscope.
• A clinical trial of surgery followed by chemoprevention.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage I non-small cell lung cancer.

Treatment of stage II non-small cell lung cancer may include the following:

• Surgery (wedge resection, segmental resection, lobectomy, or pneumonectomy).
• External radiation therapy (for patients who cannot have surgery or choose not to have surgery).
• Surgery followed by chemotherapy, with or without other treatments.
• A clinical trial of external radiation therapy following surgery.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage II non-small cell lung cancer.

Treatment of stage IIIA non-small cell lung cancer may include the following:

• Surgery with or without radiation therapy.
• External radiation therapy alone.
• Chemotherapy combined with other treatments.
• A clinical trial of new ways of giving radiation therapy and chemotherapy.
• A clinical trial of new combinations of treatments.

Treatment of stage IIIB non-small cell lung cancer may include the following:

• External radiation therapy alone.
• Chemotherapy combined with external radiation therapy.
• Chemotherapy combined with external radiation therapy, followed by surgery.
• Chemotherapy alone.
• A clinical trial of new ways of giving radiation therapy.
• A clinical trial of new combinations of treatments.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage III non-small cell lung cancer.

Treatment of stage IV non-small cell lung cancer may include the following:

• Watchful waiting.
• External radiation therapy as palliative therapy, to relieve pain and other symptoms and improve the quality of life.
• Chemotherapy.
• Laser therapy and/or internal radiation therapy.
• A clinical trial of chemotherapy with or without biologic therapy.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage IV non-small cell lung cancer.

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