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1. Merideth MA, Gordon LB, Clauss S, Sachdev V, Smith AC, Perry MB, Brewer CC, Zalewski C, Kim HJ, Solomon B, Brooks BP, Gerber LH, Turner ML, Domingo DL, Hart TC, Graf J, Reynolds JC, Gropman A, Yanovski JA, Gerhard-Herman M, Collins FS, Nabel EG, Cannon RO, Gahl WA, Introne WJ. Phenotype and course of Hutchinson-Gilford progeria syndrome. N Engl J Med 358(6): 592-604, 2008.

2. Nabel EG, Shurin SB. A recommitment to sickle cell disease research. Blood 111(10): 4852-3, 2008.

3. Nabel EG. The physician-scientist: a value proposition. J Clin Invest 118(4): 1233-5, 2008.

4. Shurin SB, Nabel EG. Pharmacogenomics--ready for prime time? N Engl J Med 358(10): 1061-3, 2008.

5. Zerhouni EA, Nabel EG. Protecting Aggregate Genomic Data. Science: 2008.


1. Capell BC, Collins FS, Nabel EG. Mechanisms of cardiovascular disease in accelerated aging syndromes. Circ Res 101(1): 13-26, 2007.

2. Crook MF, Olive M, Xue HH, Langenickel TH, Boehm M, Leonard WJ, Nabel EG. GA-binding protein regulates KIS gene expression, cell migration, and cell cycle progression. FASEB J: 2007.

3. Daar AS, Singer PA, Leah Persad D, Pramming SK, Matthews DR, Beaglehole R, Bernstein A, Borysiewicz LK, Colagiuri S, Ganguly N, Glass RI, Finegood DT, Koplan J, Nabel EG, Sarna G, Sarrafzadegan N, Smith R, Yach D, Bell J. Grand challenges in chronic non-communicable diseases. Nature 450(7169): 494-496, 2007.

4. Ganesh SK, Sharma Y, Dayhoff J, Fales HM, Van Eyk J, Kickler TS, Billings EM, Nabel EG. Detection of venous thromboembolism by proteomic serum biomarkers. PLoS ONE 2: e544, 2007.

5. Kiley JP, Nabel EG. Treating COPD. N Engl J Med 356(8): 867, 2007.

6. Nabel EG, Shurin SB, Simons-Morton DG, Gordon D. Data and safety monitoring of rosiglitazone trials. Lancet 369(9579): 2077, 2007.

7. Nabel EG, Shurin SB. Notes from the Director, National Heart, Lung, and Blood Institute: NHLBI core values and shaping the 2007 budget. Blood 110(4): 1091, 2007.

8. Nabel EG, Shurin SB. Notes From the Director, National Heart, Lung, and Blood Institute: NHLBI Core Values and Shaping the 2007 Budget. Circulation 116(6): 683-4, 2007.

9. Nabel EG, Shurin SB. Notes from the NHLBI Director: National Heart, Lung, and Blood Institute Core Values and Shaping the 2007 Budget. Am J Respir Crit Care Med 176(5): 430, 2007.

10. Nabel EG. Notes from the NHLBI director: shaping the future of research--the NHLBI strategic plan. Am J Respir Crit Care Med 176(12): 1178, 2007.

11. Nabel EG. Shaping the future of research: The NHLBI strategic plan. Blood 110(13): 4143, 2007.

12. Nabel EG. Shaping the future of research: the NHLBI strategic plan. Circ Res 101(9): 849-50, 2007.

13. Nabel EG. Notes From the Director of the National Heart, Lung, and Blood Institute: Shaping the Future of Research: The NHLBI Strategic Plan. Circulation 116(21): 2479-80, 2007.

14. True AL, Olive M, Boehm M, San H, Westrick RJ, Raghavachari N, Xu X, Lynn EG, Sack MN, Munson PJ, Gladwin MT, Nabel EG. Heme Oxygenase-1 Deficiency Accelerates Formation of Arterial Thrombosis Through Oxidative Damage to the Endothelium, Which Is Rescued by Inhaled Carbon Monoxide. Circ Res: 2007.

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1. Alexander DF, Alving BM, Battey JF, Berg JM, Collins FS, Fauci AS, Gallin JI, Grady PA, Hodes RJ, Hrynkow SH, Insel TR, Jones JF, Katz SI, Landis SC, Li TK, Lindberg DA, Nabel EG, Niederhuber JE, Pettigrew RI, Rodgers GP, Ruffin J, Scarpa A, Schwartz DA, Sieving PA, Straus SE, Tabak LA, Volkow ND. Response to: "Rescuing the NIH before it is too late" J Clin Invest: 2006.

2. Ganesh L, Yoshimoto T, Moorthy NC, Akahata W, Boehm M, Nabel EG, Nabel GJ. Protein methyltransferase 2 inhibits NF-kappaB function and promotes apoptosis. Mol Cell Biol 26(10): 3864-74, 2006.

3. Nabel EG. Conflict of interest--or conflict of priorities? N Engl J Med 355(22): 2365-7, 2006.

4. Nakahira K, Kim HP, Geng XH, Nakao A, Wang X, Murase N, Drain PF, Wang X, Sasidhar M, Nabel EG, Takahashi T, Lukacs NW, Ryter SW, Morita K, Choi AM. Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts. J Exp Med 203(10): 2377-89, 2006.

5. Spiegel AM, Nabel EG. NIH research on obesity and type 2 diabetes: providing the scientific evidence base for actions to improve health. Nat Med 12(1): 67-9, 2006.

6. Varga R, Eriksson M, Erdos MR, Olive M, Harten I, Kolodgie F, Capell BC, Cheng J, Faddah D, Perkins S, Avallone H, San H, Qu X, Ganesh S, Gordon LB, Virmani R, Wight TN, Nabel EG, Collins FS. Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A: 2006.

7. Yoshimoto T, Boehm M, Olive M, Crook MF, San H, Langenickel T, Nabel EG. The arginine methyltransferase PRMT2 binds RB and regulates E2F function. Exp Cell Res: 2006.

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1. Ganesh SK, Nabel EG. Genomics of in-stent restenosis: early insights into a complex disease. Circulation 112(16): 2378-9, 2005.

2. Nabel EG. Notes from the Director National Heart, Lung, and Blood Institute: fostering the independence of new investigators. Circulation 112(14): 2217-8, 2005.

3. Nabel EG. Notes from the NHLBI director: fostering the independence of new investigators. Am J Respir Crit Care Med 172(7): 797, 2005.

4. Nabel EG. A vision for the future: opportunities and challenges. Sleep 28(7): 788-9, 2005.

5. Nabel EG. Notes from the NHLBI Director: a vision for the future: opportunities and challenges. Am J Respir Crit Care Med 172(3): 266-7, 2005.

6. Nabel EG. A vision for the future: opportunities and challenges: notes from the director of the National Heart, Lung, and Blood Institute. Circulation 112(1): 145-6, 2005.

7. Nabel EG. A vision for the future: notes from the NHLBI director. Blood 106(2): 399-400, 2005.

8. Nabel EG. Fostering the independence of new investigators. Sleep 28(10): 1221-2, 2005.

9. Nabel EG. Interview with Dr. Elizabeth G. Nabel, Director, National Heart, Lung, and Blood Institute. Interview by Stuart F. Quan. J Clin Sleep Med 1(2): 199-201, 2005.

10. Nallamshetty S, Crook M, Boehm M, Yoshimoto T, Olive M, Nabel EG. The cell cycle regulator p27(Kip1) interacts with MCM7, a DNA replication licensing factor, to inhibit initiation of DNA replication. FEBS Lett 579(29): 6529-36, 2005.

11. Stanford SJ, Hislop AA, Oltmanns U, Nabel EG, Sang H, Haworth SG, Mitchell JA. Transition from placental to air breathing stimulates haem-oxygenase-1 expression without functional consequence for pulmonary vascular adaptation in pigs and mice. Br J Pharmacol 144(4): 467-76, 2005.

12. Zheng G, Joo J, Ganesh SK, Nabel EG, Geller NL. On averaging power for genetic association and linkage studies. Hum Hered 59(1): 14-20, 2005.

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1. Boehm M, Olive M, True AL, Crook MF, San H, Qu X, Nabel EG. Bone marrow-derived immune cells regulate vascular disease through a p27(Kip1)-dependent mechanism. J Clin Invest 114(3): 419-26, 2004.

2. Li R, Faria TN, Boehm M, Nabel EG, Gudas LJ. Retinoic acid causes cell growth arrest and an increase in p27 in F9 wild type but not in F9 retinoic acid receptor beta2 knockout cells. Exp Cell Res 294(1): 290-300, 2004.

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1. Boehm M, Nabel EG. The cell cycle and cardiovascular diseases. Prog Cell Cycle Res 5: 19-30, 2003.

2. Engel FB, Hauck L, Boehm M, Nabel EG, Dietz R, von Harsdorf R. p21(CIP1) Controls proliferating cell nuclear antigen level in adult cardiomyocytes. Mol Cell Biol 23(2): 555-65, 2003.

3. Nabel EG. Cardiovascular disease. N Engl J Med 349(1): 60-72, 2003.

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1. Akyürek LM, San H, Nabel EG, Singh R, Simari RD. Gene transfer to arteries. Curr Protoc Hum Genet Chapter 13: Unit13.1, 2002.

2. Boehm M, Nabel EG. Angiotensin-converting enzyme 2--a new cardiac regulator. N Engl J Med 347(22): 1795-7, 2002.

3. Boehm M, Yoshimoto T, Crook MF, Nallamshetty S, True A, Nabel GJ, Nabel EG. A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression. EMBO J 21(13): 3390-401, 2002.

4. Kim TH, Skelding KA, Nabel EG, Simari RD. What can cardiovascular gene transfer learn from genomics: and vice versa? Physiol Genomics 11(3): 179-82, 2002.

5. Nabel EG, Boehm M, Akyurek LM, Yoshimoto T, Crook MF, Olive M, San H, Qu X. Cell cycle signaling and cardiovascular disease. Cold Spring Harb Symp Quant Biol 67: 163-70, 2002.

6. Nabel EG. CDKs and CKIs: molecular targets for tissue remodelling. Nat Rev Drug Discov 1(8): 587-98, 2002.

7. Nabel EG. The golden egg--making good on discovery and translation. Trends Cardiovasc Med 12(1): 3-4, 2002.

8. Nabel EG. Stem cells combined with gene transfer for therapeutic vasculogenesis: magic bullets? Circulation 105(6): 672-4, 2002.

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1. Akyürek LM, Nallamshetty S, Aoki K, San H, Yang ZY, Nabel GJ, Nabel EG. Coexpression of guanylate kinase with thymidine kinase enhances prodrug cell killing in vitro and suppresses vascular smooth muscle cell proliferation in vivo. Mol Ther 3(5 Pt 1): 779-86, 2001.

2. Aoki K, Kurooka M, Chen JJ, Petryniak J, Nabel EG, Nabel GJ. Extracellular matrix interacts with soluble CD95L: retention and enhancement of cytotoxicity. Nat Immunol 2(4): 333-7, 2001.

3. Boehm M, Nabel EG. Cell cycle and cell migration: new pieces to the puzzle. Circulation 103(24): 2879-81, 2001.

4. Duckers HJ, Boehm M, True AL, Yet SF, San H, Park JL, Clinton Webb R, Lee ME, Nabel GJ, Nabel EG. Heme oxygenase-1 protects against vascular constriction and proliferation. Nat Med 7(6): 693-8, 2001.

5. Lederman RJ, Raylman RR, Fisher SJ, Kison PV, San H, Nabel EG, Wahl RL. Detection of atherosclerosis using a novel positron-sensitive probe and 18-fluorodeoxyglucose (FDG). Nucl Med Commun 22(7): 747-53, 2001.

6. Rajagopalan S, Shah M, Luciano A, Crystal R, Nabel EG. Adenovirus-mediated gene transfer of VEGF(121) improves lower-extremity endothelial function and flow reserve. Circulation 104(7): 753-5, 2001.

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1. Akyürek LM, Yang ZY, Aoki K, San H, Nabel GJ, Parmacek MS, Nabel EG. SM22alpha promoter targets gene expression to vascular smooth muscle cells in vitro and in vivo. Mol Med 6(11): 983-91, 2000.

2. Aoki K, Akyürek LM, San H, Leung K, Parmacek MS, Nabel EG, Nabel GJ. Restricted expression of an adenoviral vector encoding Fas ligand (CD95L) enhances safety for cancer gene therapy. Mol Ther 1(6): 555-65, 2000.

3. Duckers HJ, Nabel EG. Prospects for genetic therapy of cardiovascular disease. Med Clin North Am 84(1): 199-213, 2000.

4. Eitzman DT, Westrick RJ, Nabel EG, Ginsburg D. Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice. Blood 95(2): 577-80, 2000.

5. Nabel EG. Coronary heart disease in women--an ounce of prevention. N Engl J Med 343(8): 572-4, 2000.

6. Nabel EG. New approaches to pulmonary hypertension: will therapies in mice work in humans? Circulation 101(8): 839-40, 2000.

7. Sjöland H, Eitzman DT, Gordon D, Westrick R, Nabel EG, Ginsburg D. Atherosclerosis progression in LDL receptor-deficient and apolipoprotein E-deficient mice is independent of genetic alterations in plasminogen activator inhibitor-1. Arterioscler Thromb Vasc Biol 20(3): 846-52, 2000.

8. Tanner FC, Boehm M, Akyürek LM, San H, Yang ZY, Tashiro J, Nabel GJ, Nabel EG. Differential effects of the cyclin-dependent kinase inhibitors p27(Kip1), p21(Cip1), and p16(Ink4) on vascular smooth muscle cell proliferation. Circulation 101(17): 2022-5, 2000.

9. Tanner FC, Meier P, Greutert H, Champion C, Nabel EG, Lüscher TF. Nitric oxide modulates expression of cell cycle regulatory proteins: a cytostatic strategy for inhibition of human vascular smooth muscle cell proliferation. Circulation 101(16): 1982-9, 2000.

10. Yang ZY, Duckers HJ, Sullivan NJ, Sanchez A, Nabel EG, Nabel GJ. Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury. Nat Med 6(8): 886-9, 2000.

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1. Nabel EG. Delivering genes to the heart--right where it counts! Nat Med 5(2): 141-2, 1999.

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1. Danthinne X, Aoki K, Kurachi AL, Nabel GJ, Nabel EG. Combination gene delivery of the cell cycle inhibitor p27 with thymidine kinase enhances prodrug cytotoxicity. J Virol 72(11): 9201-7, 1998.

2. Nabel EG. AHA journals at the forefront of cardiology : A report on excellence Circ Res 83(8): 874-5, 1998.

3. Nabel EG. AHA journals at the forefront of cardiology : A report on excellence Hypertension 32(3): 633-4, 1998.

4. Rekhter MD, Shah N, Simari RD, Work C, Kim JS, Nabel GJ, Nabel EG, Gordon D. Graft permeabilization facilitates gene therapy of transplant arteriosclerosis in a rabbit model. Circulation 98(13): 1335-41, 1998.

5. Rekhter MD, Simari RD, Work CW, Nabel GJ, Nabel EG, Gordon D. Gene transfer into normal and atherosclerotic human blood vessels. Circ Res 82(12): 1243-52, 1998.

6. Simari RD, Yang ZY, Ling X, Stephan D, Perkins ND, Nabel GJ, Nabel EG. Requirements for enhanced transgene expression by untranslated sequences from the human cytomegalovirus immediate-early gene. Mol Med 4(11): 700-6, 1998.

7. Tanner FC, Yang ZY, Duckers E, Gordon D, Nabel GJ, Nabel EG. Expression of cyclin-dependent kinase inhibitors in vascular disease. Circ Res 82(3): 396-403, 1998.

8. Xu L, Sanchez A, Yang Z, Zaki SR, Nabel EG, Nichol ST, Nabel GJ. Immunization for Ebola virus infection. Nat Med 4(1): 37-42, 1998.

9. Yang Z, Delgado R, Xu L, Todd RF, Nabel EG, Sanchez A, Nabel GJ. Distinct cellular interactions of secreted and transmembrane Ebola virus glycoproteins. Science 279(5353): 1034-7, 1998.

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1. Arai H, Gordon D, Nabel EG, Nabel GJ. Gene transfer of Fas ligand induces tumor regression in vivo. Proc Natl Acad Sci U S A 94(25): 13862-7, 1997.

2. Nabel EG, Simari R, Yang Z, San H, Nabel GJ. In vivo gene transfer: a biological tool. Ann N Y Acad Sci 811: 289-92, 1997.

3. Ohno T, Yang Z, Ling X, Jaffe M, Nabel EG, Normolle D, Nabel GJ. Combination gene transfer to potentiate tumor regression. Gene Ther 4(4): 361-6, 1997.

4. Rodman DM, San H, Simari R, Stephan D, Tanner F, Yang Z, Nabel GJ, Nabel EG. In vivo gene delivery to the pulmonary circulation in rats: transgene distribution and vascular inflammatory response. Am J Respir Cell Mol Biol 16(6): 640-9, 1997.

5. Schott E, Tostes RC, San H, Paul M, Webb RC, Nabel EG. Expression of a recombinant preproendothelin-1 gene in arteries stimulates vascular contractility. Am J Physiol 272(5 Pt 2): H2385-93, 1997.

6. Stephan D, Gasser B, San H, Schubnel M, Nabel GJ, Nabel EG. [Direct gene transfer in the rat kidney in vivo] Arch Mal Coeur Vaiss 90(8): 1127-30, 1997.

7. Stephan D, Nabel EG. Gene and other biological therapies for vascular diseases. Fundam Clin Pharmacol 11(2): 97-110, 1997.

8. Stephan D, San H, Gordon D, Nabel GJ, Nabel EG. [Gene transfer of interferon beta inhibits vascular smooth muscle cell proliferation in vitro and in animal model of arterial injury] Arch Mal Coeur Vaiss 90(8): 1121-5, 1997.

9. Stephan D, San H, Yang ZY, Gordon D, Goelz S, Nabel GJ, Nabel EG. Inhibition of vascular smooth muscle cell proliferation and intimal hyperplasia by gene transfer of beta-interferon. Mol Med 3(9): 593-9, 1997.

10. Tanner FC, Carr DP, Nabel GJ, Nabel EG. Transfection of human endothelial cells. Cardiovasc Res 35(3): 522-8, 1997.

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1. DeBruyne LA, Chang AE, Cameron MJ, Yang Z, Gordon D, Nabel EG, Nabel GJ, Bishop DK. Direct transfer of a foreign MHC gene into human melanoma alters T cell receptor V beta usage by tumor-infiltrating lymphocytes. Cancer Immunol Immunother 43(1): 49-58, 1996.

2. Nabel GJ, Gordon D, Bishop DK, Nickoloff BJ, Yang ZY, Aruga A, Cameron MJ, Nabel EG, Chang AE. Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes. Proc Natl Acad Sci U S A 93(26): 15388-93, 1996.

3. Simari RD, Nabel EG. Genetic therapy. Semin Interv Cardiol 1(1): 77-83, 1996.

4. Simari RD, San H, Rekhter M, Ohno T, Gordon D, Nabel GJ, Nabel EG. Regulation of cellular proliferation and intimal formation following balloon injury in atherosclerotic rabbit arteries. J Clin Invest 98(1): 225-35, 1996.

5. Stephan DJ, Yang ZY, San H, Simari RD, Wheeler CJ, Felgner PL, Gordon D, Nabel GJ, Nabel EG. A new cationic liposome DNA complex enhances the efficiency of arterial gene transfer in vivo. Hum Gene Ther 7(15): 1803-12, 1996.

6. Yang Z, Simari RD, Tanner F, Stephan D, Nabel GJ, Nabel EG. Gene transfer approaches to the regulation of vascular cell proliferation. Semin Interv Cardiol 1(3): 181-4, 1996.

7. Yang ZY, Simari RD, Perkins ND, San H, Gordon D, Nabel GJ, Nabel EG. Role of the p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury. Proc Natl Acad Sci U S A 93(15): 7905-10, 1996.

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1. Chang MW, Barr E, Seltzer J, Jiang YQ, Nabel GJ, Nabel EG, Parmacek MS, Leiden JM. Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product. Science 267(5197): 518-22, 1995.

2. Chang MW, Ohno T, Gordon D, Lu MM, Nabel GJ, Nabel EG, Leiden JM. Adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene inhibits vascular smooth muscle cell proliferation and neointima formation following balloon angioplasty of the rat carotid artery. Mol Med 1(2): 172-81, 1995.

3. Fishel RS, Thourani V, Eisenberg SJ, Shai SY, Corson MA, Nabel EG, Bernstein KE, Berk BC. Fibroblast growth factor stimulates angiotensin converting enzyme expression in vascular smooth muscle cells. Possible mediator of the response to vascular injury. J Clin Invest 95(1): 377-87, 1995.

4. Nabel EG. Gene therapy for cardiovascular disease. Circulation 91(2): 541-8, 1995.

5. Nabel EG. Gene therapy for vascular diseases. Atherosclerosis 118 Suppl: S51-6, 1995.

6. Nabel GJ, Yang ZY, Nabel EG, Bishop K, Marquet M, Felgner PL, Gordon D, Chang AE. Direct gene transfer for treatment of human cancer. Ann N Y Acad Sci 772: 227-31, 1995.

7. Pompili VJ, Gordon D, San H, Yang Z, Muller DW, Nabel GJ, Nabel EG. Expression and function of a recombinant PDGF B gene in porcine arteries. Arterioscler Thromb Vasc Biol 15(12): 2254-64, 1995.

8. Yang ZY, Perkins ND, Ohno T, Nabel EG, Nabel GJ. The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo. Nat Med 1(10): 1052-6, 1995.

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1. Liptay S, Schmid RM, Nabel EG, Nabel GJ. Transcriptional regulation of NF-kappa B2: evidence for kappa B-mediated positive and negative autoregulation. Mol Cell Biol 14(12): 7695-703, 1994.

2. Muller DW, Gordon D, San H, Yang Z, Pompili VJ, Nabel GJ, Nabel EG. Catheter-mediated pulmonary vascular gene transfer and expression. Circ Res 75(6): 1039-49, 1994.

3. Nabel EG, Nabel GJ. Complex models for the study of gene function in cardiovascular biology. Annu Rev Physiol 56: 741-61, 1994.

4. Nabel EG, Plautz GE, Nabel GJ. Recombinant growth factor gene expression in vascular cells in vivo. Ann N Y Acad Sci 714: 247-52, 1994.

5. Nabel EG, Pompili VJ, Plautz GE, Nabel GJ. Gene transfer and vascular disease. Cardiovasc Res 28(4): 445-55, 1994.

6. Nabel EG, Yang Z, Muller D, Chang AE, Gao X, Huang L, Cho KJ, Nabel GJ. Safety and toxicity of catheter gene delivery to the pulmonary vasculature in a patient with metastatic melanoma. Hum Gene Ther 5(9): 1089-94, 1994.

7. Nabel GJ, Chang AE, Nabel EG, Plautz GE, Ensminger W, Fox BA, Felgner P, Shu S, Cho K. Immunotherapy for cancer by direct gene transfer into tumors. Hum Gene Ther 5(1): 57-77, 1994.

8. Nabel GJ, Nabel EG, Yang Z, Fox BA, Plautz GE, Gao X, Huang L, Shu S, Gordon D, Chang AE. Molecular genetic interventions for cancer. Cold Spring Harb Symp Quant Biol 59: 699-707, 1994.

9. Ohno T, Gordon D, San H, Pompili VJ, Imperiale MJ, Nabel GJ, Nabel EG. Gene therapy for vascular smooth muscle cell proliferation after arterial injury. Science 265(5173): 781-4, 1994.

10. Plautz GE, Nabel EG, Fox B, Yang ZY, Jaffe M, Gordon D, Chang A, Nabel GJ. Direct gene transfer for the understanding and treatment of human disease. Ann N Y Acad Sci 716: 144-53, 1994.

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1. Nabel EG, Nabel GJ. Direct gene transfer: basic studies and human therapies. Thromb Haemost 70(1): 202-3, 1993.

2. Nabel EG, Shum L, Pompili VJ, Yang ZY, San H, Shu HB, Liptay S, Gold L, Gordon D, Derynck R. Direct transfer of transforming growth factor beta 1 gene into arteries stimulates fibrocellular hyperplasia. Proc Natl Acad Sci U S A 90(22): 10759-63, 1993.

3. Nabel EG, Yang Z, Liptay S, San H, Gordon D, Haudenschild CC, Nabel GJ. Recombinant platelet-derived growth factor B gene expression in porcine arteries induce intimal hyperplasia in vivo. J Clin Invest 91(4): 1822-9, 1993.

4. Nabel EG, Yang ZY, Plautz G, Forough R, Zhan X, Haudenschild CC, Maciag T, Nabel GJ. Recombinant fibroblast growth factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivo. Nature 362(6423): 844-6, 1993.

5. Nabel GJ, Nabel EG, Yang ZY, Fox BA, Plautz GE, Gao X, Huang L, Shu S, Gordon D, Chang AE. Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proc Natl Acad Sci U S A 90(23): 11307-11, 1993.

6. Shu HB, Agranoff AB, Nabel EG, Leung K, Duckett CS, Neish AS, Collins T, Nabel GJ. Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-kappa B subunits in endothelial and epithelial cells. Mol Cell Biol 13(10): 6283-9, 1993.

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1. Nabel EG, Gordon D, Yang ZY, Xu L, San H, Plautz GE, Wu BY, Gao X, Huang L, Nabel GJ. Gene transfer in vivo with DNA-liposome complexes: lack of autoimmunity and gonadal localization. Hum Gene Ther 3(6): 649-56, 1992.

2. Nabel EG, Plautz G, Nabel GJ. Transduction of a foreign histocompatibility gene into the arterial wall induces vasculitis. Proc Natl Acad Sci U S A 89(11): 5157-61, 1992.

3. Nabel EG. Direct gene transfer into the arterial wall. J Vasc Surg 15(5): 931-2, 1992.

4. Stewart MJ, Plautz GE, Del Buono L, Yang ZY, Xu L, Gao X, Huang L, Nabel EG, Nabel GJ. Gene transfer in vivo with DNA-liposome complexes: safety and acute toxicity in mice. Hum Gene Ther 3(3): 267-75, 1992.

5. Treasure CB, Manoukian SV, Klein JL, Vita JA, Nabel EG, Renwick GH, Selwyn AP, Alexander RW, Ganz P. Epicardial coronary artery responses to acetylcholine are impaired in hypertensive patients. Circ Res 71(4): 776-81, 1992.

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1. McLenachan JM, Weidinger FF, Barry J, Yeung A, Nabel EG, Rocco MB, Selwyn AP. Relations between heart rate, ischemia, and drug therapy during daily life in patients with coronary artery disease. Circulation 83(4): 1263-70, 1991.

2. Nabel EG, Plautz G, Nabel GJ. Gene transfer into vascular cells. J Am Coll Cardiol 17(6 Suppl B): 189B-194B, 1991.

3. Nabel EG, Topol EJ, Galeana A, Ellis SG, Bates ER, Werns SW, Walton JA, Muller DW, Schwaiger M, Pitt B. A randomized placebo-controlled trial of combined early intravenous captopril and recombinant tissue-type plasminogen activator therapy in acute myocardial infarction. J Am Coll Cardiol 17(2): 467-73, 1991.

4. Nabel EG. Biology of the impaired endothelium. Am J Cardiol 68(12): 6C-8C, 1991.

5. Plautz G, Nabel EG, Nabel GJ. Selective elimination of recombinant genes in vivo with a suicide retroviral vector. New Biol 3(7): 709-15, 1991.

6. Plautz G, Nabel EG, Nabel GJ. Introduction of vascular smooth muscle cells expressing recombinant genes in vivo. Circulation 83(2): 578-83, 1991.

7. Yao SN, Wilson JM, Nabel EG, Kurachi S, Hachiya HL, Kurachi K. Expression of human factor IX in rat capillary endothelial cells: toward somatic gene therapy for hemophilia B. Proc Natl Acad Sci U S A 88(18): 8101-5, 1991.

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1. Creager MA, Hirsch AT, Dzau VJ, Nabel EG, Cutler SS, Colucci WS. Baroreflex regulation of regional blood flow in congestive heart failure. Am J Physiol 258(5 Pt 2): H1409-14, 1990.

2. Nabel EG, Plautz G, Nabel GJ. Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science 249(4974): 1285-8, 1990.

3. Nabel EG, Selwyn AP, Ganz P. Large coronary arteries in humans are responsive to changing blood flow: an endothelium-dependent mechanism that fails in patients with atherosclerosis. J Am Coll Cardiol 16(2): 349-56, 1990.

4. Nabel EG, Selwyn AP, Ganz P. Paradoxical narrowing of atherosclerotic coronary arteries induced by increases in heart rate. Circulation 81(3): 850-9, 1990.

5. Vita JA, Treasure CB, Nabel EG, McLenachan JM, Fish RD, Yeung AC, Vekshtein VI, Selwyn AP, Ganz P. Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease. Circulation 81(2): 491-7, 1990.

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1. Barry J, Mead K, Nabel EG, Rocco MB, Campbell S, Fenton T, Mudge GH, Selwyn AP. Effect of smoking on the activity of ischemic heart disease. JAMA 261(3): 398-402, 1989.

2. Gordon JB, Ganz P, Nabel EG, Fish RD, Zebede J, Mudge GH, Alexander RW, Selwyn AP. Atherosclerosis influences the vasomotor response of epicardial coronary arteries to exercise. J Clin Invest 83(6): 1946-52, 1989.

3. Nabel EG, Barry J, Rocco MB, Mead K, Selwyn AP. Effects of dosing intervals on the development of tolerance to high dose transdermal nitroglycerin. Am J Cardiol 63(11): 663-9, 1989.

4. Nabel EG, Plautz G, Boyce FM, Stanley JC, Nabel GJ. Recombinant gene expression in vivo within endothelial cells of the arterial wall. Science 244(4910): 1342-4, 1989.

5. Topol EJ, Ellis SG, Califf RM, George BS, Stump DC, Bates ER, Nabel EG, Walton JA, Candela RJ, Lee KL. Combined tissue-type plasminogen activator and prostacyclin therapy for acute myocardial infarction. Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 4 Study Group. J Am Coll Cardiol 14(4): 877-84, 1989.

6. Werns SW, Walton JA, Hsia HH, Nabel EG, Sanz ML, Pitt B. Evidence of endothelial dysfunction in angiographically normal coronary arteries of patients with coronary artery disease. Circulation 79(2): 287-91, 1989.

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1. Barry J, Selwyn AP, Nabel EG, Rocco MB, Mead K, Campbell S, Rebecca G. Frequency of ST-segment depression produced by mental stress in stable angina pectoris from coronary artery disease. Am J Cardiol 61(13): 989-93, 1988.

2. Creager MA, Hirsch AT, Nabel EG, Cutler SS, Colucci WS, Dzau VJ. Responsiveness of atrial natriuretic factor to reduction in right atrial pressure in patients with chronic congestive heart failure. J Am Coll Cardiol 11(6): 1191-8, 1988.

3. Fish RD, Nabel EG, Selwyn AP, Ludmer PL, Mudge GH, Kirshenbaum JM, Schoen FJ, Alexander RW, Ganz P. Responses of coronary arteries of cardiac transplant patients to acetylcholine. J Clin Invest 81(1): 21-31, 1988.

4. Nabel EG, Barry J, Rocco MB, Campbell S, Mead K, Fenton T, Orav EJ, Selwyn AP. Variability of transient myocardial ischemia in ambulatory patients with coronary artery disease. Circulation 78(1): 60-7, 1988.

5. Nabel EG, Berk BC, Brock TA, Smith TW. Na+-Ca2+ exchange in cultured vascular smooth muscle cells. Circ Res 62(3): 486-93, 1988.

6. Nabel EG, Ganz P, Gordon JB, Alexander RW, Selwyn AP. Dilation of normal and constriction of atherosclerotic coronary arteries caused by the cold pressor test. Circulation 77(1): 43-52, 1988.

7. Nabel EG, Shook TL, Meyerovitz M, Ganz P, Selwyn AP, Friedman PL. Detection of pacing-induced myocardial ischemia by endocardial electrograms recorded during cardiac catheterization. J Am Coll Cardiol 11(5): 983-92, 1988.

8. Rocco MB, Nabel EG, Campbell S, Goldman L, Barry J, Mead K, Selwyn AP. Prognostic importance of myocardial ischemia detected by ambulatory monitoring in patients with stable coronary artery disease. Circulation 78(4): 877-84, 1988.

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1. Barry J, Campbell S, Nabel EG, Mead K, Selwyn AP. Ambulatory monitoring of the digitized electrocardiogram for detection and early warning of transient myocardial ischemia in angina pectoris. Am J Cardiol 60(7): 483-8, 1987.

2. Nabel EG, Colucci WS, Lilly LS, Cutler SS, Majzoub JA, St John Sutton MG, Dzau VJ, Creager MA. Relationship of cardiac chamber volume to baroreflex activity in normal humans. J Clin Endocrinol Metab 65(3): 475-81, 1987.

3. Nabel EG, Rocco MB, Barry J, Campbell S, Selwyn AP. Asymptomatic ischemia in patients with coronary artery disease. JAMA 257(14): 1923-8, 1987.

4. Nabel EG, Rocco MB, Selwyn AB. Characteristics and significance of ischemia detected by ambulatory electrocardiographic monitoring. Circulation 75(6 Pt 2): V74-83, 1987.

5. Rocco MB, Nabel EG, Selwyn AP. Circadian rhythms and coronary artery disease. Am J Cardiol 59(7): 13C-17C, 1987.

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1. Campbell S, Barry J, Rebecca GS, Rocco MB, Nabel EG, Wayne RR, Selwyn AP. Active transient myocardial ischemia during daily life in asymptomatic patients with positive exercise tests and coronary artery disease. Am J Cardiol 57(13): 1010-6, 1986.

2. Campbell S, Barry J, Rocco MB, Nabel EG, Mead-Walters K, Rebecca GS, Selwyn AP. Features of the exercise test that reflect the activity of ischemic heart disease out of hospital. Circulation 74(1): 72-80, 1986.

3. Campbell S, Rocco MB, Nabel EG, Barry J, Rebecca GS, Deanfield JE, Selwyn AP. Factors determining the activity of ischemic heart disease. Am J Med 80(4C): 9-17, 1986.

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1. Nabel EG, Gibbons GH, Dzau VJ. Pathophysiology of experimental renovascular hypertension. Am J Kidney Dis 5(4): A111-9, 1985.

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