Apolipoprotein Deficiency Research Study
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Apolipoprotein Deficiency Research Study - Diagnosis and Followup Protocol
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If you have a mutation in a plasma apolipoprotein (the protein portion of a lipoprotein), you are invited to participate in a study that will evaluate the development and follow the natural history of atherosclerosis in your disorder. Many apolipoprotein mutations have been described including apolipoprotein A-I (apoA-I), apolipoprotein A-II (apoA-II), apolipoprotein B (apoB), apolipoprotein C-I (apoC-I), apolipoprotein C-II (apoC-II), apolipoprotein C-III (apoC-III) and apolipoprotein E (apoE). A variety of clinical and research techniques will be used to assess and follow the development of atherosclerosis. Recommendations for treatments will be provided based upon these findings.
Eligible persons will undergo a comprehensive evaluation. All patients will remain under the care of their own physician who will receive results of the laboratory and diagnostic tests. In most cases, you will be invited back for yearly evaluations related to other studies. There is no cost to you for travel or medical testing.
For further information please contact our research coordinator (tel. 301-496-1500, e-mail: LipidStudy@nhlbi.nih.gov).
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Disease and Treatment Information |
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Department of Health
and Human Services
National
Institutes of Health
National Heart, Lung, and Blood
Institute