CGAP       the Cancer Genome Anatomy Project
    CGAP HOW TO GenesChromosomesTissuesSAGEPathwaysTools  

Genes

Gene Tools

SNP Tools

Transcriptome Analysis

CGAP Data

Purchase CGAP Reagents

Related Links

Quick Links:

NCI Logo


Gene Info

Gene Information For:Hs. MDH1, Malate dehydrogenase 1, NAD (soluble)
Sequence ID:NM_005917

Database Links

UniGeneEntrez GeneOMIMDTPSNPViewerAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 63669635 - 63678824

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3505345Full LengthBC001484malate dehydrogenase 1, NAD (soluble)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005908  

Protein Infomation

RefSeq

mRNAProteinSwissProtEnzymePfam Motifs
NM_005917 NP_005908 P40925 EC 1.1.1.37 Ldh_1_N
Ldh_1_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U20352 AAC16436 P40925 EC 1.1.1.37
BC001484 AAH01484 P40925 EC 1.1.1.37
D55654 BAA09513 P40925 EC 1.1.1.37
AK312331 BAG35252 B2R5V5  
AK300719 BAG62394 B4DUN2  
CR457405 CAG33686 P40925 EC 1.1.1.37

Homologs (from HomoloGene)

Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MDH1 NP_005908 R.norvegicus Mdh1 24551   NP_150238 97
M.musculus Mdh1 17449 Gene Info NP_032644 96
A.gambiae AgaP_AGAP009510 1271401   XP_310186 67
D.melanogaster CG5362 34414   NP_609394 67
A.thaliana AT1G04410 839527   NP_171936 62
C.elegans F46E10.10 179041   NP_504656 60

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta

Kegg Pathways
Pathway information courtesy of Kegg


If you have any questions, comments, or need information about CGAP, please contact the NCI CGAP Help Desk.