CGAP       the Cancer Genome Anatomy Project
    CGAP HOW TO GenesChromosomesTissuesSAGEPathwaysTools  

Genes

Gene Tools

SNP Tools

Transcriptome Analysis

CGAP Data

Purchase CGAP Reagents

Related Links

Quick Links:

NCI Logo


Gene Info

Gene Information For:Hs. PPP5C, Protein phosphatase 5, catalytic subunit
Sequence ID:NM_006247

Database Links

UniGeneEntrez GeneCGWBOMIMDTPSNPViewerAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 51558131 - 51585943

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3459309Full LengthBC001970protein phosphatase 5, catalytic subunit
2961155IncompleteBC000750protein phosphatase 5, catalytic subunit
2961155IncompleteBC001831protein phosphatase 5, catalytic subunit

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006238  

Protein Infomation

RefSeq

mRNAProteinSwissProtEnzymePfam Motifs
NM_006247 NP_006238 P53041
Q53XV2
EC 3.1.3.16 Metallophos
TPR_1
PPP5

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U25174 AAB60384 P53041 EC 3.1.3.16
BC000750 AAH00750 Q9BPW0  
BC001831 AAH01831 Q9BPW0  
BC001970 AAH01970 P53041
Q53XV2
EC 3.1.3.16
BT007275 AAP35939 P53041
Q53XV2
EC 3.1.3.16
AB209615 BAD92852 Q59F46  
AK223222 BAD96942 Q53FR0  
AK312683 BAG35563 B2R6R6  
AK293402 BAG56909 B4DDZ8  
AK297095 BAG59608 B4DLP6  
X89416 CAA61595 P53041 EC 3.1.3.16
X92121 CAA63089 P53041 EC 3.1.3.16

Homologs (from HomoloGene)

Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PPP5C NP_006238 M.musculus Ppp5c 19060 Gene Info NP_035285 98
R.norvegicus Ppp5c 65179   NP_113917 98
D.melanogaster PpD3 49779   NP_731398 63
A.gambiae AgaP_AGAP004151 1273977   XP_313034 61
C.elegans pph-5 180263   NP_741697 60
A.thaliana PAPP5/PP5 818881   NP_001031534 55
M.grisea MGG_06941 2685114   XP_370444 54
N.crassa NCU01433.1 2710141   XP_327872 51
S.pombe SPBC3F6.01c 2541004   NP_596740 51
S.cerevisiae PPT1 853023   NP_011639 45

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

Kegg Pathways
Pathway information courtesy of Kegg


If you have any questions, comments, or need information about CGAP, please contact the NCI CGAP Help Desk.