Testing Information

Testing Status of Agents at NTP

Asphalt Table 6

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Table 6. Summary of mutagenicity data for asphalt and coal-tar pitch fume condensates*



Fume generation temperature (°C)

Source of fume
condensates
163 221232 316 MI

Roofing asphalt No.2 ------ +--- 12 (1)
No.2 ------ ---+ 10 (1)
No.3 --- --- + --- 12 (2)
No.3 --- --- --- + 10 (1)
Paving asphalt** + --- --- --- 14††
--- +‡‡ --- --- 18§§ (13)
Type I Coal tar pitch --- --- + ---725 (35)
--- --- --- + 1555 (75)

* Adapted from Machado et al. [1993].

The slope of the dose-response curve, i.e., revertants per ml of dosing solution (± asymptotic standard error).

Two Type III roofing asphalts representing different crude sources were used. One of the roofing asphalts was air-blown using ferric chloride as a catalyst (no. 3) and the other was air-blown without the use of a catalyst (no. 2).

** Eighteen samples of paving asphalt fume condensates representing 14 crude oil sources and various process conditions were used.

†† Mean of 37 experiments on 17 paving asphalt samples. One to three experiments were run for each sample; MIs ranged from 5 to 49, and the MIs for the pooled data ranged from 6 to 29.

‡‡ One paving asphalt was generated and tested at 221°C.

§§ Mean of three experiments.