Billing Code: 4163-18-P

U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

Support Services from the World Health Organization (WHO) for the President’s Emergency Plan for HIV/AIDS Relief

Announcement Type: New

Funding Opportunity Number: CDC-RFA-PS08-872 

Catalog of Federal Domestic Assistance Number: 93.067

Key Dates:

Application Deadline: October 10, 2008

 

I. Funding Opportunity Description

Authority: This program is authorized under Sections 301(a) and 307 of the Public Health Service Act [42 U.S.C. Sections 241 and 242l], as amended, and under Public Law 108-25 (United States Leadership Against HIV/AIDS, Tuberculosis and Malaria Act of 2003) [22 U.S.C. 7601], and under the Tom Lantos and Henry J. Hyde United States Global Leadership Against HIV/AIDS, Tuberculosis, and Malaria Reauthorization Act of 2008.

 

Background:

President Bush's Emergency Plan for AIDS Relief has called for immediate, comprehensive and evidence-based action to turn the tide of global HIV/AIDS. The initiative aims to treat more than two million HIV-infected people with effective combination anti-retroviral therapy (ART) by 2008; care for ten million HIV-infected and affected persons, including those orphaned by HIV/AIDS, by 2008; and prevent seven million infections by 2010, with a focus on 15 priority countries, including 12 in sub-Saharan Africa.  The Five-Year Strategy for the Emergency Plan is available at the following Internet address:  http://www.state.gov/s/gac/plan/c11652.htm

 

Purpose:

Under the leadership of the U.S. Global AIDS Coordinator, as part of the President's Emergency Plan, the U.S. Department of Health and Human Services (HHS) and the Centers for Disease Control and Prevention (CDC) works with host countries and other key partners to assess the needs of each country and design a customized program of assistance that fits within the host nation's strategic plan.

 

HHS/CDC focuses on two or three major program areas in each country.  Goals and priorities include the following:

 

 

The purpose of this announcement is to provide an avenue for technical assistance and collaboration with country and regional programs in countries within sub-Saharan Africa, Eastern Europe, Asia, the Pacific, and the Americas; as well as to U.S. Federal partners, based on objectives consistent with those established for the international community by a collaborative effort among ten United Nations agencies that sponsor the Joint United Nations Programme on HIV/AIDS (UNAIDS).

 

The purpose of this announcement is to provide services to support a framework of interventions based on objectives consistent with those established for the international community by WHO in countries within sub-Saharan Africa, Eastern Europe, Asia, the Pacific, and the Americas. The focus of this program is to strengthen international standards and technical guidance provided to programs to prevent, control, care, and treat HIV/AIDS in the following areas: 1) HIV care and treatment; 2) laboratory; 3) Prevention of Mother to Child Transmission (PMTCT) & pediatric care and treatment; 4) HIV prevention;  5) strategic information (Health Management Information Systems (HMIS), disease surveillance, Monitoring and Evaluation (M&E), statistical and mathematical modeling); and, 6) capacity building.  Any proposals for the collection and reporting of data (e.g., disease surveillance, program evaluation, public-health evaluation) will require submission of protocols for review by HHS/CDC, and the submission of specific budgets for each of these activities, which must detail the cost for personnel and administrative overhead.  The administrative overhead costs may not exceed five percent of the award.

 

Measurable outcomes of the program will be in alignment with the Emergency Plan’s general indicators and the Emergency Plan’s Five-Year Strategy, which are:

  1. Five sets of  international guidelines developed, updated, and/or disseminated in support of HIV care and treatment; laboratory; PMTCT & pediatric care and treatment; HIV prevention;  strategic information (HMIS, disease surveillance, M&E, statistical and mathemathical modeling); and capacity building.
  2. Train 100 local public health providers in host countries in the monitoring and evaluation of HIV care and treatment; laboratory; PMTCT & pediatric care and treatment; HIV prevention;  strategic information (HMIS, disease surveillance, M&E, statistical and mathematical modeling); and capacity building.
  3. 30 organizations provided with technical assistance to adapt, implement and improve M&E activities in the following areas: HIV care and treatment; laboratory; PMTCT & pediatric care and treatment; HIV prevention;  strategic information (HMIS, disease surveillance, M&E, statistical and mathematical modeling); and capacity building.
  4. 50 persons trained in host countries in data analysis, report-writing and standard-based HMIS approaches in support of HIV care and treatment; laboratory; PMTCT & pediatric care and treatment; HIV prevention;  strategic information  (HMIS, disease surveillance, M&E, statistical and mathematical modeling); and capacity building.
  5. 15 Governments supported in the implementation of HIV care and treatment; laboratory; PMTCT & pediatric care and treatment; HIV prevention;  strategic information (HMIS, disease surveillance, M&E, statistical and mathematical modeling); and capacity building.
  6. 15 Governments supported to finalize national laboratory strategic plans; 15 Governments supported to adopt an established and validated HIV testing algorithm.
  7. Five organizations assisted to adopt approaches based on data standards when developing software systems for HMIS purposes.

 

This announcement is intended for non-research activities supported by HHS/CDC.  For the definition of “research,” please see the HHS/CDC Web site; at the following Internet address: http://www.cdc.gov/od/science/regs/hrpp/researchdefinition.htm

 

Activities:

The recipient of these funds is responsible for activities in multiple program areas designed to target underserved populations in sub-Saharan Africa, Eastern Europe, Asia, the Pacific, and the Americas.  The recipient must show a measurable, progressive reinforcement of the capacity of indigenous organizations and local communities to respond to the national HIV epidemic, as well as progress towards the sustainability of activities.

The recipient should describe activities in detail that reflect the policies and goals outlined in the Five-Year Strategy for the President’s Emergency Plan.

The recipient will produce an annual operational plan with specific activities and products, which the U.S. Government Emergency Plan headquarters team will review as part of the annual process to review and approve the Emergency Plan Headquarters Operational Plan, managed by the Office of the U.S. Global AIDS Coordinator.  The recipient may work on some of the activities listed below in the first year and in subsequent years, and then progressively add others from the list to address other Emergency Plan performance goals, as cited in the previous section.  HHS/CDC, under the guidance of the U.S. Global AIDS Coordinator, will approve funds for activities on an annual basis, based on documented performance toward achieving Emergency Plan goals, as part of the annual Emergency Plan for AIDS Relief Country Operational Plan review-and-approval process.

 

The overarching activities for the duration of this Cooperative Agreement include the following, as specified in the described technical areas:

1.    Care and Treatment

o        Provide guidance documents and other materials to improve the level of HIV care in developing countries. 

o        Assist in the development of strategies to improve care and treatment training in developing countries; and assist in the implementation of training plans.

o        Assist in the monitoring of new and existing HIV care programs in developing countries; assist in the development and roll-out of standardized assessment instruments for monitoring the quality of HIV care.

o        Assist in the evaluation of human-resource requirements for providing quality care in developing countries; provide advocacy on the importance of human resource development in the tiered model of service provision.

o        Provide advocacy for the importance of supporting the provision of quality pharmacy and drug procurement (HIV and OI drugs) in support of care.

o        Assist in developing guidance for community mobilization (including the use of PLWHA) in support of care and treatment (adherence support, prevention in positives, etc.); provide advocacy for such mobilization in-country.

o        Assist in developing guidance on the importance of care and treatment in preventing HIV transmission.

Specific examples of Year 1 activities in care and treatment include the following:

I.  Strengthening Human Resources, the control of Multi Drug Resistant-Tuberculosis (TB), and TB-related Infection Control in the Federal Democratic Republic of Ethiopia, including the following:

1.    Training staff in the Ethiopian Federal Ministry of Health and clinicians in TB specialty hospitals;

2.    Providing technical assistance to develop a strategy for TB-related infection control; and

3.    Evaluating the status of TB/HIV programs and the impact of staff added in FY07 in host countries.

II. Strengthening the Delivery of Care in Ethiopia through the following:

  1. Tailoring and adapting local-language training materials and programs for the IMAI/IMCI (Integrated Management of Adolescent and Adult Illnesses/Integrated Management of Childhood Illnesses) Second-Level HIV Clinical-Learning Program;
  2. Conducting the training of trainers, and pre-service and in-service training for the IMCI/IMAI Second-Level HIV Clinical-Learning Program; and   
  3. Providing professional exchanges for government and university senior clinician mentors from the Ethiopian Government and local universities, in collaboration with other WHO programs in Africa.

 

III. Scaling-up HIV Prevention, Care, and Anti-Retroviral Therapy at Primary Health Centers (IAMI) in the United Republic of Tanzania, including the following:

  1. Updating, reviewing, translating, printing and disseminating IMAI guidelines, training packages, patient-monitoring tools, and the operational manual, in local languages;  
  2. Convening biannual, national meetings with all partners that are implementing care and treatment services in Tanzania, to share experiences and document best practices;
  3. Conducting an orientation of IMAI training to teachers from Tanzanian health-training institutions for nurses, assistant medical officers and clinical officers; and  
  4. Adapting, printing, and disseminating WHO guidelines and training packages for clinical mentoring and supportive supervision for ART.

IV. Assisting with capacity-building for the roll-out of a standardized approach to measuring performance and improving quality in HIV clinical care in Papua New Guinea and the People’s Republic of Laos, including the following;

  1. Establishing mechanisms for TB and HIV/AIDS programs to work together to decrease the burden of TB in PLWHA, and to decrease the burden of HIV in TB patients;
  2. Providing technical assistance to develop TB/HIV action plans and systems to monitor progress in scale-up;

3. Developing training packages in local languages for all levels of       health staff to help health-care institutions in these countries   to put recent guidelines related to TB/HIV in effect;

4. Adapting and disseminating the tools the WHO has developed for    reporting and recording and the monitoring tools for caring for HIV patients on ART; and

5. Providing technical assistance to countries as they mobilize      resources, and to maintain active involvement in the “Treat,   Train, and Retain” initiative of the WHO Department of HIV/AIDS.   

 

2.    Laboratory

  1. The Diagnosis and Surveillance of HIV and Opportunistic Infections (OI)

·         Improving coordination for laboratory activities in developing countries through technical guidance, policy, training, quality assurance, and support of HIV care, the diagnosis of OIs; and ARV therapy for member countries;

·         Assisting with the roll-out of the HIV rapid-testing training package, and the implementation of the accompanying quality- assurance guidelines;

·         Providing guidance on HIV-testing strategies and algorithms, including strategies for infant testing and early diagnosis;

·         Assisting with the preparation and review of HIV/AIDS-related training packages and guidelines, particularly for CD4 technologies;

·         Organizing and chairing regional meetings and workshops related to HIV testing, clinical laboratory technologies, and laboratory quality-assurance programs; and

·         Assisting in responding to queries related to HIV/AIDS diagnostics and clinical laboratory issues.

b. Laboratory Performance

·         Improving the quality of laboratory performance by implementing training packages for HIV rapid testing, and pilot- testing the joint training packages developed by the HHS/CDC and WHO for CD4-enumeration technologies package at regional meetings in Africa, Europe, South-East Asia, and the Western Pacific;

·         Establishing and/or strengthening quality-assurance programs for HIV serology and clinical laboratory testing;

·         Organizing a multi-partner consensus on clinical laboratory testing through training and the implementation of quality- assurance programs;

·         Supporting improved performance and implementation of PMTCT and pediatric-related testing for HIV; and

·         Working to improve information systems that store and analyze lab data.

c.   Training

·         Developing and printing manuals and course curricula, including in local languages.   

Specific examples of Year 1 activities in Laboratory include the following:

I.                    Performing external quality-assessment schemes, and developing standardized testing procedures in laboratories that are conducting laboratory tests related to HIV, Sexually Transmitted Infections (STI), and TB in Papua New Guinea and the Peoples Republic of Laos.

II.                 Providing technical assistance to strengthen laboratory standards and to build the local capacity of Emergency Plan laboratory programs, including the following:

  1. Sponsoring meetings between African Ministries Of Health laboratory directors, to establish a network of reference on the African continent;
  2. Developing guidance on the standardization of laboratory supplies and commodities;
  3. Developing generic guidelines on strategic planning for national Government laboratory systems, based on existing country plans;
  4. Updating HIV-testing strategies adopted for international use, with a particular emphasis on provider-initiated and home-based testing;
  5. Updating quality-assurance guidance on HIV-related testing, consistent with international standards; and
  6. Establishing guidelines for setting the validation of HIV-testing algorithms.

 

3.    Prevention of Mother-to-Child Transmission and Pediatric Care and Treatment

·         Reviewing international guidelines and policy, and making recommendations for policy and technical updates or revisions to these guidelines and policies;

·         Advocating and organizing meetings and reviews to promote policy changes at the national, regional and international levels; support regional and national planning & capacity building for the delivery of PMTCT and HIV care for children; supporting the integration of PMTCT programs with Maternal and Child Health and ART programs; 

·         Developing best-practice guidelines for programs that deliver PMTCT and pediatric care and treatment, including routine or provider-initiated testing, optimal anti-retroviral prophylaxis and treatment, infant feeding, and linkages to care and treatment and pediatric follow-up and diagnosis;

·         Supporting the integration of PMTCT and pediatric monitoring and evaluation in national monitoring-and-evaluation (M&E) systems; and

·         Facilitating global and interagency coordination through the leadership of the Interagency Task Team (IATT); and coordinating program activities with the Emergency Plan, UNITAID, the Global Fund and other UN efforts.

Specific examples of Year 1 activities in PMTCT include the following:

I. Assisting with the development of PMTCT-specific guidance, capacity- building and training of local staff in local languages, and improving the monitoring of PMTCT programs in Papua New Guinea.

II. Providing technical assistance to support and strengthen international guidelines and coordination on PMTCT, including the following:

1.    Updating pediatric treatment guidelines, based on new and emerging evidence for different and more effective treatment strategies;

2.    Completing the revision of the national PMTCT/Pediatric M&E guidance;

3.    Completing WHO guidance on infant diagnosis;

4.    Disseminating the Global Guidance for the Scale-Up of PMTCT Programs; and

5.    Developing a plan and framework to coordinate WHO PMTCT funding from new grants with Emergency Plan funding and activities in Emergency Plan countries.

 

4.    Strategic Information

  1. Health Information-Management Systems
    • Developing and refining information-exchange standards; pilot-testing developed messages to exchange data between electronic medical records (EMR) systems;
    • Developing toolkits to be available to software developers on the Internet to facilitate the implementation of message- generation and parsing; meeting to discuss progress, experiences, and evaluation;
    • Preparing, pilot-testing, and publishing a set of guidance documents to help with system assessment and evaluation, in order to evaluate objectively and implement competing health-information and management systems; developing guidance for implementation, deployment, staffing, and effective partnerships with private industry to assist country staff and Ministry counterparts in scaling up their ART activities. Guidance should also address how HMIS fits within the larger context of information systems, including but not limited to, EMRs;
    • Developing software for use in ART and PMTCT facilities, voluntary counseling and testing (VCT) centers, and orphans and vulnerable children (OVC) or other community-based programs; and
    • Providing logistics training; in addition, provide monitoring of training programs, and software to support laboratory testing and quality assurance.

Specific examples of Year 1 activities in HMIS include the following:

I. Health Metrics Network (HMN)

1.    Coordinate common HMN Wave Two/Emergency Plan country assessments of health-information systems (HIS);

2.    Adapting the HMN framework for integrating HIV-related systems into national HIS in Emergency Plan countries;

3.    Contributing to the development of the HMN collaborative Internet presence around HIS;

4.    Collaborating on information and communication technology (ICT), data, and M&E standards, best practices, and guidelines; 

5.    Providing technical assistance to supplement HMN that is facing effective national- and programmatic M&E and HIS implementation;

6.    Supporting capacity-building in health information technology (with University of Washington) in country; and

7.    Promoting HIS policy development and guidelines.

 

II. Support the increased use of electronic medical records (EMR) systems and learning systems in clinical settings:

1.    Conducting site visits with organizations that are using EMRs for analyzing software and hardware technology;

2.    Assisting Ministries of Health to adopt appropriate software technology;

3.    Establishing scale-up strategies for working EMR systems;

4.    Developing and disseminating standards-based frameworks;

5. Developing and expanding an HL7-based standardized medical-record-   exchange messages; and

6. Documenting the feasibility of an EMR standard approach to AIDS care by incorporating this functionality in the OpenMRS-HIV software product.

b.    Surveillance

·         Collaborating on the tools and methods for HIV/AIDS case- reporting by using revised HIV clinical staging and case definitions derived from previous regional consultantions; reviewing and modifing case reporting guidelines, and  assisting with pilot testing;

·         Refining the WHO protocol to pilot test surveys of drug- resistance thresholds surveys; refining the WHO protocol to monitor ARV drug resistance in treated patients; and, assisting with the implementation of pilot tests in several countries;

·         Modifying the WHO guidelines for sentinel surveillance, and assisting countries with data-analysis and writing reports;

·         Refining methods to sample high-risk populations to obtain better data on HIV cases, prevention, treatment and care for behavioral surveillance;

·         Implementing training programs on surveillance methods at regional and national levels;

·         Developing surveillance evaluation guidelines;

·         Promote integration, coordination and reporting in PMTCT programs; and

·         Developing new international ethical guidelines for HIV- surveillance activities; hosting a series of ethics consultations in the WHO regions to address ethical concerns about HIV-testing policies in the context of surveillance activities.

Specific examples of Year 1 activities in surveillance include the following:

I.    Strengthening of surveillance data in Russia:

1.    Building the capacity of HIV surveillance staff at the Russian Ministry of Health by training them on the analysis of existing data, data triangulation, and investigation of cases identified;  

2.    Building laboratory capacity of the Russian routine surveillance system (BED or ‘son-of-BED’ capacity, and, possibly, a pooled NAT testing pilot);

3.    Providing TA to improve the analysis of existing, routine HIV surveillance data in the two oblasts; 

4.    Extending surveillance to “bridge groups” and perform a baseline threshold ARV drug-resistance survey;

5.    Finalizing and disseminating the guidelines in Russian print, CD ROM and the Internet.

 

III. HIV case-reporting

1.    Developing protocols and providing technical assistance to those countries identified as wanting to improve their HIV/AIDS case reporting. 

 

IV. International database on ARV drug resistance

1.    Continuing to maintain the database and provide training manual for users.

c.    Monitoring and Evaluation

  • Writing and publishing a comprehensive set of guidelines for maintaining the security and confidentiality of patient information used in HIV care and treatment programs. These guidelines should apply to all data, from paper-based forms to electronic medical records and data warehouses. They should also discuss the protection of information within facilities that collect data, the protection of information extracted from these facilities for reporting purposes, and how to construct and use appropriately the analytic datasets that balance the need for the information with the need to protect patient and institutional confidentiality;
  • Supporting the adaptation, training, and implementation of HIV care/ART patient-monitoring systems; support outcomes-monitoring and evaluation activities of national ART programs;
  • Supporting HIV care and treatment impact-evaluation studies, and pilot novel programmatic approaches and evaluate the implementation of these approaches;
  • Supporting the monitoring of prevention activities, especially those in medical-care settings like TB clinics and HIV care and treatment facilities, and conduct evaluations of HIV-prevention programs;     
  • Supporting development and improvement of PMTCT monitoring indicators, and systems; supporting PMTCT evaluation studies to demonstrate best practices; and, generally promoting improved data collection, analysis, and use of data from HIV programs, including PMTCT, TB/HIV care, and ART.      

Specific examples of Year 1 activities in M&E include the following:

I. Monitoring and Evaluation Support from the WHO to National AIDS Control Program (NACP) in Tanzania by:

1.    Providing technical assistance to NACP to coordinate, maintain, and use existing national HIV/AIDS information systems, including to monitor all current systems concerning HIV/AIDS information; coordinating and training trainers, and sub-national trainers on the systems and use of data; developing supervision protocols for the quality and use of data and data feedback on these protocols; setting up systems at the national level that ensure data quality at all levels of the system, including data and reports that flow from sub-national to national levels; advocate for the use of electronic information to generate and disseminate reports for improving programs.

 II. Develop, adapt and disseminate M&E guidelines, and evaluate national M&E systems

d.    Statistical and Mathematical Models

  • Developing statistical and mathematical models for estimating and projecting the course of the HIV epidemic in countries throughout the world, including estimates for HIV incidence, prevalence, mortality and orphans, as well as survival for persons on ART therapy, the potential spread of HIV drug resistance, and HIV infections averted.  Include in these models parameters related to uncertainty in the estimates and projections; and
  • Developing software, as appropriate, for the implementation of these methods and train public health officials in the use of this software.

5.    HIV Prevention

  • Developing guidelines and recommendations, and build capacity to expand blood-safety and injection-safety activities;
  • Provide training and support for TB/HIV counseling and testing activities in-country; and
  • Developing guidelines and recommendations, and build capacity to expand confidential HIV counseling and testing.

Specific examples of Year 1 activities in Prevention include the following:

I.                Develop a national plan and training for both counseling and laboratory testing services in Papua New Guinea;

 

II. Provide TA to spearhead the acceleration of prevention, including the integration of prevention across HIV programming in the Republic of Kenya; and

 

III. Provide technical assistance to strengthen the local capacity of confidential Emergency Plan provider-initiated testing and counseling (PITC) programs, including:

1.    Developing, adapting and disseminating PITC guidance;

2.    Providing South-South technical assistance on PITC;

3.    Documenting current best practices in PITC; and

4.    Rolling-out of new M&E guidelines for PITC.

 

IV. Provide technical assistance for the development and rolling-out of male circumcision programs, including the following: 

a. Establishing standards and provide policy and program guidance for the provision of safe male circumcision;

b. Providing technical support to roll out safe male circumcision s in selected countries;

c. Developing global communication strategies and messages;

d. Coordinating global research priority-setting, and establishing indicators for monitoring and evaluating male circumcision and its impact within HIV-prevention programming; and

e. Ensuring quality-control/quality-assurance practices.

 

V.  Identify and develop policies to strengthen the integration of safe blood transfusion into health care institutions:

a.  Organizing “Africa Summit on Blood Safety”  for transfusion services from across Africa to meet and participate in high-level technical discussions; and

b. Developing, printing, and disseminating lessons learned from experience in strengthening of national blood services through the Emergency Plan program.

 

VI. Support the Safe-Injection Global Network

a. Developing policies in injection safety relating to phlebotomy, the riskiest common procedure for HIV transmission in health-care facilities; and

b. Distribute the "SIGNpost" weekly, a moderated Internet forum that reaches more than 1,000 subscribers in the six WHO regions, by facilitating informal discussions and the sharing of experience.

 

6. Capacity Building

·         Foster collaboration between other groups that are working on various infectious diseases and other related program areas, such as polio eradication, measles elimination, malaria, TB/HIV, routine immunization, to maximize linkage between those programs.     

 

Administration

The recipient must comply with all HHS/CDC management requirements for meeting participation and progress and financial reporting for this cooperative agreement (See HHS/CDC Activities and Reporting sections below for details), and comply with all policy directives established by the Office of the U.S. Global AIDS Coordinator.

 

In a cooperative agreement, HHS/CDC staff are substantially involved in the program activities, above and beyond routine grant monitoring. 

HHS/CDC Activities for this program are as follows:

1.    Organize an orientation meeting with the recipient to brief the applicable U.S. Government, HHS, and Emergency Plan expectations, regulations and key management requirements, as well as report formats and contents.  The orientation could include meetings with staff from HHS/CDC agencies and the Office of the U.S. Global AIDS Coordinator.

2.    Review and approve the recicpient’s annual work plan and detailed budget, as part of the Emergency Plan for AIDS Relief Country Operational Plan review-and-approval process, managed by the Office of the U.S. Global AIDS Coordinator.

3.    Review and approve the recipient’s monitoring-and-evaluation plan, including compliance with the strategic-information guidance established by the Office of the U.S. Global AIDS Coordinator. 

4.    Meet on a monthly basis with the recipient to assess monthly expenditures in relation to approved work plan and modify plans, as necessary.  Meetings via teleconference are an acceptable alternative for this purpose.

5.    Meet on a quarterly basis with the recipient to assess quarterly technical and financial progress reports and modify plans as necessary.

6.    Meet on an annual basis with the recipient to review annual progress report for each U.S. Government Fiscal Year, and review annual work plans and budgets for subsequent year, as part of the Emergency Plan for AIDS Relief review and approval process for Country Operational Plans, managed by the Office of the U.S. Global AIDS Coordinator.

7.    Provide technical assistance, as mutually agreed upon, and revise annually during validation of the first and subsequent annual work plans.  This could include expert technical assistance and targeted training activities in specialized areas, such as strategic information, project management, confidential counseling and testing, palliative care, treatment literacy, and adult-learning techniques.  

8.    Provide in-country administrative support to help recipient meet U.S. Government financial and reporting requirements approved by the Office of Management and Budget (OMB) under 0920-0428 (Public Health Service Form 5161)

9.    Collaborate with the recipient on designing and implementing the activities listed above, including, but not limited to the provision of technical assistance to develop program activities, data management and analysis, quality assurance, the presentation and possibly publication of program results and findings, and the management and tracking of finances.

10.Provide consultation and scientific and technical assistance based on appropriate, HHS/CDC and Office of the U.S. Global AIDS Coordinator documents to promote the use of best practices known at the time.

11.Assist the recipient in developing and implementing quality-assurance criteria and procedures.

12.Facilitate in-country planning and review meetings for technical assistance activities      

 

Please note: Either HHS/CDC staff or staff from organizations that have successfully competed for funding under a separate HHS/CDC contract, cooperative agreement or grant will provide technical assistance and training.

 

II. Award Information

Type of Award: Cooperative Agreement

HHS/CDC involvement in this program appears in the Activities Section above. HHS/CDC reserves the right to negotiate and agree upon example activities every budget cycle prior to funding of those activities.

Award Mechanism: U2G - Global HIV/AIDS Non-Research Cooperative Agreements

Fiscal Year Funds: 2008

Approximate Current Fiscal Year Funding: $9,500,000

Approximate Total Project Period Funding: $48,000,000 (This amount is an estimate, and is subject to availability of funds.  Individual countries may add additional funding each year as funding becomes available for expanded or additional activities.) 

Approximate Number of Awards: 1

Approximate Average Award: $9,500,000 (This amount is for the first 12-month budget period, and includes direct costs (and indirect costs in the case of domestic grantees.)

Floor of Individual Award Range: $500,000

Ceiling of Individual Award Range: $15,000,000 (This ceiling is for the first 12-month budget period.)

Anticipated Award Date: September 30, 2008

Budget Period Length: 12 Months

Project Period Length: 5 Year

Throughout the project period, HHS/CDC’s commitment to continuation of this award is on the availability of funds, evidence of satisfactory progress by the recipient (as documented in required reports), and the determination that continued funding is in the best interest of the U.S. Government, through the Emergency Plan for AIDS Relief review and approval process for Country Operational Plans, managed by the Office of the U.S. Global AIDS Coordinator.

 

III. Eligibility Information

III.1. Eligible applicant:

The World Health organization (WHO)

The World Health Organization (WHO) is the United Nations specialized agency for health. It is the directing and coordinating authority for global health issues. WHO was established on Apr 7, 1948. The WHO currently has 193 Member States through the World Health Assembly. The Health Assembly is composed of representatives from WHO's Member States. WHO also has regional organizations in Africa, the Eastern Mediterranean, South-east Asia & the Pacific, Europe, the Western Pacific, and the Americas. In developing countries, WHO develops health standards, provides technical guidance and supports the strengthening of indigenous health care system capacity. No outside government or private organization can establish health standards for sovereign nations but, because WHO is part of the United Nations, standards developed by WHO are widely accepted by developing nations. Furthermore, no organization is more respected for building surveillance, laboratory or health care standards. The organization is known and recognized worldwide and is highly influential with sovereign governments when establishing health care standards and practices. Acting under the authority of the United Nations, the WHO launched the Global Program on AIDS in 1987 and took the lead in the UN global health response to the HIV/AIDS pandemic. The WHO has established an extensive presence in the regions of the world that are most heavily impacted by the HIV/AIDS pandemic. No other known source has such an extensive and established international presence devoted to a comprehensive and sustainable response to HIV/AIDS. Also, many of the technical requirements for HIV/AIDS prevention build upon programs that were originally developed by the WHO, such as integrated management of adolescent and adult illness (IMAI) and the 3 by 5 initiative, hence making it vital that the organization continue to build upon these efforts for maximum impact. The Global AIDS Program (GAP) was created at the direction of Congress in FY2000, and HIV/AIDS program offices were established in 25 countries and 4 regional offices in Africa, Asia & the Pacific, and the Caribbean. GAP's mission is to prevent transmission of HIV infection, improve HIV/AIDS treatment, care and support, and build international capacity to address the HIV/AIDS pandemic. This Single Eligibility award to WHO will help GAP achieve its mandated goals. It will allow GAP to benefit from WHO's influence, manpower and ability to develop widely accepted international health guidelines and set international standards. The WHO is the only organization that possesses necessary experience to provide the immediate and continuing technical support to combat the HIV/AIDS pandemic in the following areas: a. HIV Care and Treatment b. Laboratory c. Preventing Mother-to-Child Transmission d. HIV Prevention e. Strategic Information (inlcuding HMIS, surveillance, M&E, and statistical and mathematical modeling) h. Capacity Building

 

III.2. Cost-Sharing or Matching

Matching funds are not required for this program.  However, the recipient may demonstrate their ability to leverage additional funds to contribute to program goals. If the recipient receives funding from other sources to underwrite the same or similar activities, or anticipate receiving such funding in the next 12 months, please provide detail how the disparate streams of financing complement each other.

III.3. Other

Special Requirements:

  • Note: Title 2 of the United States Code Section 1611 states that an organization described in Section 501(c)(4) of the Internal Revenue Code that engages in lobbying activities is not eligible to receive Federal funds constituting a grant, loan, or an award.

 

IV. Application and Submission Information

IV.1. Address to Request Application Package

To apply for this funding opportunity use application form PHS 5161-1.

 

Electronic Submission:

HHS/CDC strongly encourages the applicant to submit the application electronically by using the forms and instructions posted for this announcement on www.Grants.gov, the official Federal agency-wide Egrant Web site. 

If recipient encounters technical difficulties with Grants.gov, please contact customer service by email at support@grants.gov, or by phone 1-800-518-4726 (1-800-518-GRANTS).  The Customer Support Center is open from 7:00 a.m. to 9:00 p.m. Eastern Standard Time, Monday through Friday. 

 

IV.2. Content and Form of Submission

Application: The applicant must submit a project narrative with the application forms, in the following format:

Maximum number of pages: 25 (Font size: 12-point, unreduced;

  • Double-spaced;
  • Paper size: 8.5 by 11 inches, or generally accepted paper size;
  • Page-margin size: One-inch;
  • Number all pages of the application sequentially from page one (Application Face Page) to the end of the application, including charts, figures, tables, and appendices;
  • The narrative should address activities the applicant will conduct over the entire project period, and must include the following items, in the order listed:
  • Project Context and Background (Understanding and Need):  Describe the background and justify the need for the proposed project.  Describe the current infrastructure system; targeted geographical area(s), if applicable; and identified gaps or shortcomings of the current health systems and AIDS-control project.
  • Project Strategy - Description and Methodologies:  Present a detailed operational plan for initiating and conducting the project.  Clearly describe the applicant’s technical approach/methods for implementing the proposed project.  Describe the existence of or plans to establish partnerships necessary to implement the project.  Describe linkages, if appropriate, with programs funded by the U.S. Agency for International Development;
  • Project Goals and Objectives:  Describe the overall goals of the project, and specific objectives that are measurable and time-phased, consistent with the objectives and numerical targets of the President’s Emergency Plan and for this Cooperative Agreement program as provided in the “Purpose” Section at the beginning of this Announcement;
  • Project Outputs:  The applicant should address each of the program objectives listed in the “Purpose” Section of this Announcement.  Measures must be specific, objective and quantitative so as to provide meaningful outcome evaluation;
  • Project Contribution to the Goals and Objectives of the President’s Emergency Plan for AIDS Relief:  Provide specific measures of effectiveness to demonstrate accomplishment of the objectives of this program; 
  • Work Plan and Description of Project Components and Activities:  The applicant should address each of the specific tasks listed in the Activities section of this Announcement.  Clearly identify specific assigned responsibilities for all key professional personnel; 
  • Performance Measures:  Measures must be specific, objective and quantitative;
  • Timeline (e.g., GANNT Chart); and
  • Management of Project Funds and Reporting.

 

The applicant may include additional information in appendices.  The appendices and budget information will not count toward the narrative page limit. This additional information includes the following:

  • Project Budget and Justification:

With staffing breakdown and justification, provide a line-item budget and a narrative with justification for all requested costs.

Budgets must be consistent with the purpose, objectives of the Emergency Plan and the program activities listed in this announcement and must include the following:

o        Line-item breakdown and justification for all personnel, i.e., name, position title, annual salary, percentage of time and effort, and amount requested.

For each contract and subcontract, list the following: (1) name of proposed contractor; (2) breakdown and justification for estimated costs; (3) description and scope of activities the contractor will perform; (4) period of performance; (5) method of contractor selection (e.g., competitive solicitation); and (6) methods of accountability.  The applicant should, to the greatest extent possible, employ transparent and open competitive processes to choose contractors; 

 

  • Curricula vitae of current staff who will work on the activity;
  • Job descriptions of proposed key positions to be created for the activity;
  • Applicant’s Corporate Capability Statement;
  • Evidence of Legal Organizational Structure.

 

Additional requirements that could require submission of additional documentation with the application appear in Section “VI.2.  Administrative and National Policy Requirements.”

 

IV.3. Submission Dates and Times

Application Deadline Date: October 10, 2008

 

Electronic Submission: 

HHS/CDC will consider application completed online through Grants.gov as formally submitted when the applicant organization’s Authorizing Official electronically submits the application to www.grants.gov on or before the deadline date and time. The application will be electronically time/date stamped, which will serve as receipt of submission.  Applicants will receive an email notice of receipt when HHS/CDC receives the application.

 

IV.4. Intergovernmental Review of Applications

Executive Order 12372 does not apply to this program.

 

IV.5. Funding Restrictions

  • The recipient may not use funds for research.

·         Needle Exchange - No funds appropriated under this Act shall be used to carry out any program of distributing sterile needles or syringes for the hypodermic injection of any illegal drug.

·         The recipient may spend funds for reasonable program purposes, including personnel, training, travel, supplies and services.  The recipient may purchase equipment and complete renovations if deemed necessary to accomplish program objectives, and if authorized by, and in accordance with, applicable U.S. Government Federal Laws and HHS/CDC policy in a transparent and competitive manner.

·         The applicant shall state all requests for funds contained in the budget in U.S. dollars. Once HHS/CDC makes an award, HHS/CDC will not compensate for currency-exchange fluctuations through the issuance of supplemental awards.

·         The costs generally allowable in grants to domestic organizations are allowable to foreign institutions and international organizations, with the following exception: With the exception of the American University, Beirut, and the World Health Organization, HHS/CDC will not pay indirect costs (either directly or through sub-award) to organizations located outside the territorial limits of the United States or to international organizations, regardless of their location.

·         The recipient may contract with other organizations under this program. However, the recipient must perform a substantial portion of the activities (including program management and operations, and delivery of prevention services for which funds are required) relating to the management of sub-grants to local organizations and improving their capacity, and must award any subcontracts through a competitive and transparent process.

 

Prostitution and Related Activities

 

The U.S. Government is opposed to prostitution and related activities, which are inherently harmful and dehumanizing, and contribute to the phenomenon of trafficking in persons. 

 

Any entity that receives, directly or indirectly, U.S. Government funds in connection with this document (“recipient”) cannot use such U.S. Government funds to promote or advocate the legalization or practice of prostitution or sex trafficking.  Nothing in the preceding sentence shall be construed to preclude the provision to individuals of palliative care, treatment, or post-exposure pharmaceutical prophylaxis, and necessary pharmaceuticals and commodities, including test kits, condoms, and, when proven effective, microbicides. 

 

A recipient that is otherwise eligible to receive funds in connection with this document to prevent, treat, or monitor HIV/AIDS shall not be required to endorse or utilize a multisectoral approach to combating HIV/AIDS, or to endorse, utilize, or participate in a prevention method or treatment program to which the recipient has a religious or moral objection.  Any information provided by recipients about the use of condoms as part of projects or activities that are funded in connection with this document shall be medically accurate and shall include the public health benefits and failure rates of such use.

 

In addition, any recipient must have a policy explicitly opposing prostitution and sex trafficking.  The preceding sentence shall not apply to any “exempt organizations” (defined as the Global Fund to Fight AIDS, Tuberculosis and Malaria, the World Health Organization and its six Regional Offices, the International AIDS Vaccine Initiative or any United Nations agency).

 

The following definition applies for purposes of this clause:

·         Sex trafficking means the recruitment, harboring, transportation, provision, or obtaining of a person for the purpose of a commercial sex act.  22 U.S.C. § 7102(9).

 

The recipient must insert provisions implementing the applicable parts of this section, “Prostitution and Related Activities,” in all sub-agreements under this award.  These provisions must be express terms and conditions of the sub-agreement, must acknowledge that compliance with this section, “Prostitution and Related Activities,” is a prerequisite to receipt and expenditure of U.S. Government funds in connection with this document, and must acknowledge that any violation of the provisions shall be grounds for unilateral termination of the agreement prior to the end of its term. The recipient must agree that HHS/CDC may, at any reasonable time, inspect the documents and materials maintained or prepared by the recipient in the usual course of its operations that relate to the organization’s compliance with this section, “Prostitution and Related Activities.”

 

All prime recipients that receive U.S. Government funds (“prime recipients”) in connection with this document must certify compliance prior to actual receipt of such funds in a written statement that makes reference to this document (e.g., “[Prime recipient's name] certifies compliance with the section, “Prostitution and Related Activities.”) addressed to the agency’s grants officer.  Such certifications by prime recipients are prerequisites to the payment of any U.S. Government funds in connection with this document. 

 

Recipient compliance with this section, “Prostitution and Related Activities,” is an express term and condition of receiving U.S. Government funds in connection with this document, and any violation of it shall be grounds for unilateral termination by HHS/CDC of the agreement with HHS/CDC in connection with this document prior to the end of its term.  The recipient shall refund to HHS/CDC the entire amount furnished in connection with this document in the event HHS/CDC determines the recipient has not complied with this section, “Prostitution and Related Activities.”

Budget

Guidance for completing the budget appears on the HHS/CDC Web site, at the following Internet address:

http://www.cdc.gov/od/pgo/funding/budgetguide.htm

 

IV.6. Other Submission Requirements

Application Submission Address:

Electronic Submission:

HHS/CDC strongly encourages the electronic submission of the application through www.Grants.gov.  The application package is available at www.Grants.gov.  The applicant may complete the application off-line, then upload and submit the application via the Grants.gov web site.  HHS/CDC will not accept email submissions.  If the applicant has technical difficulties in Grants.gov, the applicant should contact Grants.gov customer service by email at support@grants.gov, or by phone at 1-800-518-4726 (1-800-518-GRANTS).  The Customer Support Center is open from 7:00 a.m. to 9:00 p.m., Eastern Time, Monday through Friday. 

 

HHS/CDC recommends submission of the application to Grants.gov early enough to resolve any unanticipated difficulties prior to the deadline. 

HHS/CDC strongly recommends applicants submit the grant application by using Microsoft Office products (e.g., Microsoft Word, Microsoft Excel, etc.).  If the applicant does not have access to Microsoft Office products, the applicant may submit a PDF file.  Directions for creating PDF files are available on the Grants.gov web site.  Use of file formats other than Microsoft Office or PDF could make the file unreadable for our staff.

V. Application Review Information

V.1. Criteria

The applicant is required to provide specific measures of effectiveness that will demonstrate the accomplishment of the various identified objectives of the cooperative agreement. Measures of effectiveness must relate to the performance goals stated in the “Purpose” section of this announcement.  Measures must be objective and quantitative, and must measure the intended outcome.  The applicant must submit the measures of effectiveness with the application, and they will be an element of evaluation.

 

HHS/CDC will evaluate the application against the following criteria:

 

Ability to Carry Out the Proposal

Does the applicant demonstrate the local experience and institutional capacity (both management and technical) to achieve the goals of the project with documented good-governance practices?  Does the applicant have the ability to coordinate and collaborate with existing Emergency Plan partners and other donors, including the Global Fund and other U.S. Government departments and agencies involved in implementing the Emergency Plan, including the U.S. Agency for International Development?  Is there evidence of leadership support and evidence of current or past efforts to enhance HIV prevention?  Does the applicant have the capacity to reach rural and other underserved populations?  Does the applicant organization have the ability to target audiences that frequently fall outside the reach of the traditional media, and in local languages? 

 

Technical and Programmatic Approach

Does the applicant include an overall design strategy, including measurable time lines, clear monitoring-and-evaluation procedures, and specific activities for meeting the proposed objectives?  Does the applicant display knowledge of the strategy, principles and goals of the President's Emergency Plan for AIDS Relief, and are the proposed activities consistent with and pertinent to that strategy and those principles and goals?  Does the applicant describe activities that are evidence-based, realistic, achievable, measurable and culturally appropriate to achieve the goals of the Emergency Plan?  Does the applicant propose to build on and complement the current national responses with evidence-based strategies designed to reach underserved populations and meet the goals of the Emergency Plan?  Does the applicant include reasonable estimates of outcome targets?  (For example, the numbers of sites to be supported, number of clients the program will reach.)  To what extent does the applicant propose to work with other organizations?  The reviewers will assess the feasibility of the applicant's plan to meet the target goals, whether the proposed use of funds is efficient, and the extent to which the specific methods described are sensitive to the local culture.

 

Capacity-Building

Does the applicant have a proven track-record of building the capacity of indigenous organizations and individuals?  Does the applicant have relevant experience in using participatory methods and approaches, in project planning and implementation?  Does the applicant describe an adequate and measurable plan to progressively build the capacity of local organizations and of target beneficiaries to respond to the epidemic? If not a local indigenous organization, does the applicant articulate a clear exit strategy, which will maximize the legacy of this project in the intervention communities?  Does the capacity-building plan clearly describe how it will contribute to a) improved quality and geographic coverage of service delivery to achieve the "2, 7, 10[1]" targets of the Emergency Plan, and b) (if not a local indigenous organization) an evolving role of the prime beneficiary with transfer of critical technical and management competence to local organizations/sites in support of a decentralized response?

 

Monitoring and Evaluation

Does the applicant demonstrate the local experience and capability to implement rigorous monitoring and evaluation of the project?  Does the applicant describe a system for reviewing and adjusting program activities based on monitoring information obtained by using innovative, participatory methods and standard approaches?  Does the plan include a solid evaluation plan?  Is the system able to generate financial and program reports to show disbursement of funds, and progress towards achieving the numerical objectives of the President's Emergency Plan?  Is the plan to measure outcomes of the intervention, and the manner in which they will be provided, adequate?  Is the monitoring-and-evaluation plan consistent with the principles of the "Three Ones[2]?"  The applicants must define specific output and outcome indicators must be defined in the proposal, and must have realistic targets in line with the targets addressed in the Activities section of this announcement.

 

Understanding of the Problem

Does the applicant demonstrate a clear and concise understanding of the current global HIV/AIDS response and the cultural and political context relevant to the programmatic areas targeted?  Does the applicant display an understanding of the Five-Year Strategy and goals of the President's Emergency Plan?  To what extent does the applicant justify the need for this program?

 

Personnel

Does the organization employ staff fluent in local languages who will work on this project?  Are the staff roles clearly defined?  As described, will the staff be sufficient to meet the goals of the proposed project?  If not an indigenous organization, does the staff plan adequately involve local individuals and organizations?  Are staff involved in this project qualified to perform the tasks described?  Curricula vitae provided should include information that they are qualified in the following:  management of HIV/AIDS prevention activities, especially confidential, voluntary counseling and testing; and the development of capacity-building among and collaboration between Governmental and non-governmental partners.

Administration and Management

Does the applicant provide a clear plan for the administration and management of the proposed activities, and to manage the resources of the program, prepare reports, monitor and evaluate activities, audit expenditures and produce collect and analyze performance data?  Is the management structure for the project sufficient to ensure speedy implementation of the project?  If appropriate, does the applicant have a proven track record in managing large budgets; running transparent and competitive procurement processes; supervising consultants and contractors; using subgrants or other systems of sharing resources with community-based organizations, faith based organizations or smaller non-governmental organizations; and providing technical assistance in management?  The grantee must demonstrate an ability to submit quarterly reports in a timely manner to the HHS/CDC office.

 

Budget

Is the itemized budget for conducting the project, along with justification, reasonable and consistent with stated objectives and planned program activities?  Is the budget itemized, well-justified and consistent with the Five-Year Strategy (2003-2008) and goals of the President's Emergency Plan and Emergency Plan activities?  If applicable, are there reasonable costs per client reached for both year one and later years of the project?

 

V.3. Anticipated Announcement and Award Dates

The anticipated award date is September 30, 2008.

 

VI. Award Administration Information

VI.1. Award Notices

The applicant will receive a Notice of Award (NoA) from the HHS/CDC Procurement and Grants Office.  The NoA shall be the only binding, authorizing document between the recipient and HHS/CDC.  An authorized Grants Management Officer will sign the NoA, and mail it to the recipient fiscal officer identified in the application.

 

VI.2. Administrative and National Policy Requirements

The recipient must comply with the administrative requirements outlined in 45 CFR Part 74 and Part 92 as Appropriate.  The following additional requirements apply to this project:

  • AR - 4      HIV/AIDS Confidentiality Provisions.       
  • AR - 6      Patient Care.      
  • AR - 9      Paperwork Reduction Act Requirements.      
  • AR - 10     Smoke-Free Workplace Requirements.   
  • AR - 11     Healthy People 2010.     
  • AR - 12     Lobbying Restrictions.   
  • AR - 14     Accounting System Requirements.             
  • AR - 23     Compliance with 45 C.F.R. Part 87.   
  • AR - 24     Health Insurance Portability and Accountability Act Requirements.  
  • AR - 25     Release and Sharing of Data.   

Additional information on the requirements is available on the HHS/CDC Web site, at the following Internet address: http://www.cdc.gov/od/pgo/funding/ARs.htm.

 

For more information on the Code of Federal Regulations, see the National Archives and Records Administration, at the following Internet address: http://www.access.gpo.gov/nara/cfr/cfr-table-search.html

 

The applicant must include an additional Certifications form from the PHS5161-1 application in the Grants.gov electronic submission.  The applicant should refer to the following Internet address:

http://www.cdc.gov/od/pgo/funding/PHS5161-1-Certificates.pdf.  Once the applicant has completed the form, the applicant should attach it to the Grants.gov submission as “Other Attachments Form”.

 

VI.3. Reporting Requirements

The recipient must provide HHS/CDC with an original, plus two hard copies, of the following reports:

1.    Interim progress report, due no less than 90 days before the end of the budget period.  The progress report will serve as the non-competing continuation application, and must contain the following elements:

a.    Activities and Objectives for the Current Budget Period;

b.    Financial Progress for the Current Budget Period;

c.    Proposed Activity and Objectives for the New Budget Period Program;

d.    Formal Budget;

e.    Measures of Effectiveness, including progress against the numerical goals of the President's Emergency Plan for AIDS Relief for Headquarters; and

f.    Additional Requested Information;

2.    Annual progress report, due 90 days after the end of the budget period.  Reports should include progress against the numerical goals of the President's Emergency Plan for AIDS Relief for Headquarters;

3.    Financial status report, due no more than 90 days after the end of the budget period; and

4.    Final financial performance reports, due no more than 90 days after the end of the project period.

The recipient must mail the reports to the Grants Management or Contract Specialist listed in the "Agency Contacts" section of this announcement.

 

 

VII. Agency Contacts

HHS/CDC encourages inquiries concerning this announcement.

For general questions, contact:

      Technical Information Management Section

      Procurement and Grants Office

      Centers for Disease Control and Prevention

      U.S. Department of Health and Human Services

      2920 Brandywine Road

      Atlanta, GA 30341

      Telephone: 770-488-2700

 

For program technical assistance, contact:

        Theresa Diaz, Project Officer

      Centers for Disease Control and Prevention

      U.S. Department of Health and Human Services

Telephone: (404)639-6312

E-mail: txe1@cdc.gov

 

For financial, grants management, or budget assistance, contact:

Diane Flournoy, Grants Management Specialist

      Procurement and Grants Office

      Centers for Disease Control and Prevention

      U.S. Department of Health and Human Services

      2920 Brandywine Road, Mail stop: K-75

      Atlanta, GA 30341

      Telephone: (770) 488-2072

      E-mail: dmf6@cdc.gov

 

VIII. Other Information

Other HHS/CDC funding opportunity announcements are available on the HHS/CDC Web site, Internet address: http://www.cdc.gov ( Click on “Funding” then “Grants and Cooperative Agreements.”), and on the web site of the HHS/CDC Office of Global Health Affairs, Internet address: www.globalhealth.gov.

 

 


 

[1] The “2,7,10” initiative aims to treat more than two million HIV infected people with effective combination anti-retroviral therapy (ART) by 2008; prevent seven million infections by 2010, with a focus on 15 priority countries, including 12 in sub-Saharan Africa; and care for ten million HIV infected and affected persons, including those orphaned by HIV/AIDS, by 2008.

[2] PEPFAR establishes bilateral programs in host countries and also works closely with multilateral partners, such as the Global Fund to Fight AIDS, Tuberculosis and Malaria and the United Nations program on AIDS (UNAIDS), as well as local Faith-Based Organizations. PEPFAR also endorses the international principles of the "Three Ones": — one national plan, one national coordinating authority, and one national monitoring and evaluation system in each of the host countries in which organizations work.

 

CDC Home Page: http://www.cdc.gov

CDC Funding Web Page: http://www.cdc.gov/od/pgo/funding/FOAs.htm  

CDC Forms Web Page: http://www.cdc.gov/od/pgo/funding/grants/app_and_forms.shtm