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 Thursday, August 30, 2007 Volume 19   Number 9
Weekly Update banner Family History Population Research Genomics in Practice General Public Family History Population Research Genomics in Practice General Public
  This weekly update provides information about the impact of human genetic research on disease prevention & public health. open mailbox for email deliveryGet email updates
Spotlight
Sections
image of test tubes Roldolfo Valdez speaking at the  NBNA Conference

Direct-to-Consumer Genomic Tests
In a national survey, CDC found 14% of consumers were aware of nutrigenomic tests, and 0.6% reported using them. 44% of physicians were aware of these tests and 74% had never discussed the results with a patient.
> Read scientific article pdf icon (334KB)

Special Genomics Session
Dr. Rodolfo Valdez of CDC presented on healthcare and family history during a genomics session at the National Black Nurses Association conference from July 25-27, 2007, in Atlanta, GA.

> View his presentation PDF icon
 > View Current Update
blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 

 

 

 

 

Genomics Announcements
   
bullhorn

Federal Agency rejects enhanced oversight of genetic tests, places cost considerations above public health concerns

   
bullhorn

September public health genomics seminar presented by CDC
“How do we monitor the impact of genomics on population health?"
Sep 20, 2007, Rockville, MD (ENVISION – Atlanta, GA)


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Cancer

UK scientists identify gene's key role in breast cancer developmentnon-gov warning icon Medical News Today, August 30

Elective surgery was the best way for woman to douse fuse on cancer's genetic time bomb,  non-gov warning icon Evansville Courier & Press, August 27

A gene for metastasisnon-gov warning icon EurekAlert, August 28

Black women and breast cancernon-gov warning icon CBS News, August 27

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Chronic Diseases

Hunting the gene that traps children in their own worldnon-gov warning icon Times Online, August 27

Genetic clues to ALS, Newsday.com, August 24

‘We ask ourselves, can we separate Alex and autism?’non-gov warning icon Times Online, August 27

 

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Genetic Testing

Ethical, Legal, and Social Issues (ELSI)

San Francisco chronicle examines field of direct-to-consumer genetic testingnon-gov warning icon Medical News Today, August 29

Do not ask or do not answernon-gov warning icon Economist.com, August 23
UNC study questions FDA genetic-screening guidelines for cancer drugnon-gov warning icon EurekAlert, August 28  

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Other News

American Lung Association examines ongoing disparities driven by socioeconomic and genetic factorsnon-gov warning icon Medical News Today, August 29

Options in genetic engineeringnon-gov warning icon The Hindu, August 27

Human Genetics Department at Leiden University Medical Center (LUMC) adopts Fluidigm biomark(TM) Real-time PCR Systemnon-gov warning icon (last accessed 2/2008) Forbes.com, August 29

Response by American College of Medical Genetics to new FDA labeling decision for
warfarin
non-gov warning icon Medical News Today, August 27

Smoking turns on genes – permanentlynon-gov warning icon
EurekAlert, August 29

NIH scientists discover novel cause of iron overload in thalassemia disordersnon-gov warning icon NIH News, August 26

Gene tied to post-op delirium in elderlynon-gov warning icon
MedicineNet.com, August 28

Novel approach used to uncover genetic components of agingnon-gov warning icon News Medical.Net, August 26

New understanding of factor YY1 in gene expressionnon-gov warning icon News-Medical.Net, August 28

Epidemiologist sees flaws in papers on genes and gendernon-gov warning icon Science, August 24

One gene may be key to perfect pitchnon-gov warning icon The Sydney Morning Herald, August 28

Sanger on cusp of genetics history,  
Businessweekly.co.uk, August 24

Transcription factor's control of gene expression illuminatednon-gov warning icon Science Daily, August 28

Bits of 'junk' RNA aid master tumor-suppressor genenon-gov warning icon  EurekAlert, August 23

New Alzheimer's findings: High stress and genetic risk factor lead to increased memory decline,  non-gov warning icon
EurekAlert, August 27
 
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Genomics in Scientific Literature
Featured Item

Claims of sex differences: an empirical assessment in genetic associations
Patsopoulos NA, et al.
JAMA 2007 Aug;298(8):880-93

 General Articles

Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance
Crimmins NA & Martin LJ
Obes Rev 2007 Sep;8(5):419-23

G>C SNP of thymidylate synthase with respect to colorectal cancer
Gusella M & Padrini R
Pharmacogenomics 2007 Aug;8(8):985-96

Pharmacogenetics of the response to beta2 agonist drugs: a systematic overview of the field
Contopoulos-Ioannidis DG, et al.
Pharmacogenomics 2007 Aug;8(8):933-58

Pharmacogenetics of thiazolidinedione therapy
Aquilante CL
Pharmacogenomics 2007 Aug;8(8):917-31

beta(2)-adrenoceptor polymorphisms and obstructive airway diseases: important issues of study design
Yang IA, et al.
Clin Exp Pharmacol Physiol 2007 Oct;34(10):1029-36

Pharmacogenetics as a tool for optimising drug therapy in solid-organ transplantation
Ng FL, et al.
Expert Opin Pharmacother 2007 Sep;8(13):2045-58

Eating disorders: an overview of treatment responses and the potential impact of  vulnerability genes and endophenotypes
Ramoz N, et al.
Expert Opin Pharmacother 2007 Sep;8(13):2029-44

Genome-wide association scans identify multiple confirmed susceptibility loci for Crohn's disease: Lessons for study design
Tremelling M & Parkes M
Inflamm Bowel Dis 2007 Aug

Genetic Polymorphisms of the Endocannabinoid System
Norrod AG & Puffenbarger RA
Chem Biodivers 2007 Aug;4(8):1926-32

Impact of common genetic variation on neonatal disease and outcome
Harding D
Arch Dis Child Fetal Neonatal Ed 2007 Sep;92(5):F408-F413

Dietary, physiological, genetic and pathological influences on postprandial lipid metabolism
Lopez-Miranda J, et al.
Br J Nutr 2007 Sep;98(3):458-73

The endothelium and genetics in pulmonary arterial hypertension
Nicod L
Swiss Med Wkly 2007 Aug;137(31-32):437-42

Genetics of body mass stability and risk for chronic disease: a 28-year longitudinal study
Franz CE, et al.
Twin Res Hum Genet 2007 Aug;10(4):537-45

Pharmacogenetics of morphine: Potential implications in sickle cell disease
Darbari DS, et al.
Am J Hematol 2007 Aug

Bayesian inference of epistatic interactions in case-control studies
Zhang Y & Liu JS
Nat Genet 2007 Aug

Genetic associations in peripheral joint osteoarthritis and spinal degenerative disease: a systematic review
Ryder JJ, et al.
Ann Rheum Dis 2007 Aug

Unraveling intrinsic genetic factors in type 2 diabetes
Katzov H
Clin Genet 2007 Sep;72(3):184-5

 

 Genetic Testing

Attitudes regarding carrier testing in incompetent children: a survey of European clinical geneticists
Borry P, et al.
Eur J Hum Genet 2007 Aug

 

 Family History

Implications of family history of myocardial infarction in young women
Patel MJ, et al.
Am Heart J 2007 Sep;154(3):454-60

Family history of urogenital cancers in patients with bladder, renal cell and prostate cancers
Randi G, et al.
Int J Cancer 2007 Aug

Efficacy of personal symptom and family history questionnaires when screening for inherited cardiac pathologies? The role of electrocardiography
Wilson MG, et al.
Br J Sports Med 2007 Aug

 
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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending August 29, 2007, there are HuGE articles in the following areas:

Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Certain Conditions Originating in the Perinatal Period
Symptoms, Signs, and Ill-defined Conditions

For more information on HuGE, please visit the HuGENet™ home page

 

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 Provides link to non-governmental sites and does not necessarily represent the views of the Centers  for Disease Control and Prevention.
Page last reviewed: August 30, 2007 (archived document)
Content Source: National Office of Public Health Genomics