Use the health topic menu below to find reviews that are in development.
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Dopamine Receptor, D2 (DRD2) Genotype and Drinking Behaviour/Alcohol Dependency
David Foxcroft et al. (Oxford Brookes University) |
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A systematic review of association studies of osteoarthritis
Alex MacGregor (University of East Anglia, UK) |
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Interactive effects of antioxidant genes and air pollution on respiratory symptoms: a HuGE systematic review
Cosetta Minelli1, Gurdeep Sagoo2, Igor Wei1, Debbie Jarvis1, Seif Shaheen1, Peter Burney1
1Respiratory Epidemiology & Public Health Group, National Heart and Lung Institute, Imperial College London
2UK HuGENet Coordinating Centre, Strangeways Research Lab, Worts Causeway, Cambridge, and MRC Biostatistics Unit, Institute of Public Health, Forvie Site, Cambridge
Proposed Date: 8/5/2008 |
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Influence of the ADRB2 gene polymorphisms on the response to β2-agonists in airway diseases: a HuGENet systematic review and meta-analysis
Matteo Bonini1, Cosetta Minelli2, John Thompson3, Keith Abrams3, Peter Burney2
1 Department of Internal Medicine, University of Genoa, Italy
2 Respiratory Epidemiology & Public Health Group, National Heart and Lung Institute, Imperial College, London
3 Medical Statistics Group, Department of Health Sciences, University of Leicester, Leicester
Proposed Date: 7/7/2008 |
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Polymorphisms of Glutathione-S-transferase genes and asthma: a HuGE systematic review and meta-analysis including unpublished data
John Henderson, Raquel Granell and Sue Ring (ALSPAC, Department of Social Medicine, University of Bristol)
Seif Shaheen, Cosetta Minelli and Roger Newson (Respiratory Epidemiology & Public Health Group, National Heart and Lung Institute, Imperial College London)
John W Holloway and Matthew Rose-Zerilli (Asthma Genetics Group, Division of Infection, Inflammation & Repair and Division of Human Genetics, University of Southampton)
Proposed Date: 1/2/2008 |
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IgE Pathway Polymorphisms and Asthma
Kate Reed (CDC) |
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The association between PDCD1 Gene and Systemic Lupus Erythematosus
Jie Zhang (Department of Epidemiology, School of Public Health, University of Alabama at Birmingham)
Grier Page (Dept. of Biostatistics, School of Public Health, University of Alabama at Birmingham)
Proposed Date: 7/25/2007
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The association between HLA-DRB1 and SLE in the mainland in China—a mini Meta-analysis
Zhenglun Pan (Shandong provincial hospital, China) |
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CTLA-4 gene polymorphisms and the susceptibility to autoimmune thyroid disease
John P. Ioannidis
(Univ of Ioannina School of Medicine, Greece) |
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CFTR mutations in cystic fibrosis and congenital bilateral absence of the vas deferens (CBAVD)
Shauna Lyn (Centers for Disease Control and Prevention) |
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MTHFR and cleft lip and palate
Una B. Fallon and George Davey Smith (University of Bristol, United Kingdom) |
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XRCC1 Genetic Polymorphisms and Prostate Cancer Susceptibility: A HuGENet Systematic Review and Meta-analysis
Hai-feng Zhang1, Fei Liu2, Li-guang Zhu1, Yan Wang1, Xiaoping Qian3
1 No. 1 Hospital Affiliated to GuangXi Medical University
2 The People's Hospital of GuangXi Zhuang Autonomous Region
3 Nanjing Drum Tower Hospital
Proposed Date: 09/6/2008 |
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Genes involved in the inflammatory pathway and lung cancer risk
Darren R. Brenner and Rayjean J. Hung
(University of Toronto, Canada)
(Samuel Lunenfeld Research Institute, Toronto, Canada)
Proposed Date: 08/14/2008 |
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Genetic variation as a potential mediator of NSAID prophylaxis for colorectal neoplasia
Alex Demarsh, Alex Yurkewiech, Julian Little (Department of Epidemiology and Community Medicine, University of Ottawa )
Proposed Date: 05/28/2008 |
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NQO1 and Childhood Leukemia
Anand Chokkalingam (UC Berkeley School of Public Health)
Proposed Date: 08/08/2007 |
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Alcohol, aldehyde dehydrogenase-2 polymorphism and head and neck cancer risk: a meta-analysis of the literature
Stefania Boccia (Catholic University of Sacred Heart, Italy)
Proposed Date: 11/20/2006 |
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Associations between polymorphisms in iron metabolism genes and gastrointestinal cancers
Valerie K. Tait (University of Ottawa)
Proposed Date: 11/03/2006 |
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The glutathione S-transferase variants as possible risk factors for hepatocellular carcinoma
Hashem El-Serag and Donna L. White (Baylor College of Medicine) |
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GSTM1, CYP1A1 and smoking and lung cancer
Gurdeep Sagoo and Julian Higgins (Public Health Genetics Unit, Cambridge, UK) |
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NAT1, NAT2 and cigarette smoking and bladder cancer
Simon Sanderson, Julian Higgins, and Georgia Salanti (Cambridge Public Health Genetics Unit, UK) |
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Genes regulating the inflammatory response (IL1B, IL1RN, TNFA, IL10 and IL8) in relation to gastric cancer and gastric precancerous conditions
David Forman (University of Leeds, UK) |
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Bladder Cancer: GSTT1.
Klaus Golka (University of Dortmund, Germany)
International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens |
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Bladder Cancer: NAT.
Jian-hua Shen (Chinese Academy of Sciences, Shanghai, China)
International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens |
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Bladder Cancer: NAT2, GSTM1.
Paul Nelson / Mireille Toledano (Imperial College London, UK)
International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens |
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Breast Cancer: CYP1B1.
Velentina Paracchini (Fondazione Policlinico IRCCS, Milan, Italy)
International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens |
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Colorectal Cancer R: CYP1A1.
Julian Little (University of Ottawa, Canada)
International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens |
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Esophageal Cancer: CYP2E1, GSTM1, GSTT1, GSTP1.
Luis Felipe Ribeiro Pinto (Universidade do Estado do Rio de Janeiro, Brazil)
International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens |
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Lung Cancer: gene-gene interaction.
Paolo Vineis / Maria De Iorio (Imperial College London, UK)
International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens |
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Lung Cancer: GSTP1.
Michele Cote (Wayne State University; Detroit, MI, USA)
International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens |
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Lung Cancer: NQO1.
Cathryn Bock (Wayne State Universit ; Detroit, MI, USA)
International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens |
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Colorectal Cancer: GSTs, NATs.
Julian Little (University of Ottawa, Canada) and Richard Hayes (National Cancer Institute, Bethesda, MARYLAND, USA).
International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens |
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Oral and Pharingeal Cancer: GSTM1, mEH, CYP1A1.
Alberto Ruano-Ravina (University of Santiago de Compostela, Spain)
International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens |
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NAT2 and breast cancer
Heather M. Ochs-Balcom (Case Western Reserve University, Cleveland, OH) |
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Association of Polymorphisms in Oxidative Stress-related Genes (MnSOD, GPx, MPO, NQO1, EPHX1) with Breast Cancer: A HuGE Gene-disease Association Review
Christos Ntais, P. A. Kyzas, Anastasia Polycarpou and John P.
Ioannidis
(Univ of Ioannina School of Medicine, Greece) |
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Genetic Polymorphisms in Base Excision Repair Pathways (XRCC1, OGG1 and APEX1) and Cancer Risk: a HuGE Gene-disease Association Review
Rayjean J. Hung, Paul Brennan, Paolo Boffetta
(International Agency for Research on Cancer) |
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N-acetyltransferase-2 polymorphisms and lung cancer: a HuGE Gene-disease Association Mini-review
Huei-Ting Tsai (Univ of North Carolina, Chapel Hill) |
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Genetic polymorphisms and risk of childhood leukemia
Daniel Sinnett (U. of Montreal) |
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BRCA1/BRCA2 and Ovarian Cancer
Roxana Moslehi and Lawrence Brody (NIH) |
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BRCA1/BRCA2 and Breast Cancer
Roxana Moslehi and Lawrence Brody (NIH) |
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Glutathion S-Transferase M1 (GSTM1) and Lung Cancer
Chris Carlsten (Univ of Washington), Wylie Burke (Univ of Washington) |
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I1307K Variant of APC/Colon Cancer
S. Gruber (U. of Michigan) |
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NAT2 and Bladder Cancer
G. DeBord, M. Butler, K. Cheever, T. Reid (NIOSH) |
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ALDH2/Esophageal and Oropharyngolaryngeal Cancers
M. Young (U. of Oklahoma) |
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Melanocortin-1 receptor gene (MC1R) and cutaneous neoplasms (basal cell carcinoma, squamous cell carcinoma, and melanoma)
Peter Kanetsky (University of Pennsylvania) |
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CD14 Genetic Polymorphism and Ischemic Heart Disease
Hai-Feng Zhang1, Bao-Liang Zhong2, Li-Guang Zhu1, Yan Wang1, Lei Lei1, Li-Xin Qiu3
1 Department of Cardiology, Institute of Cardiovascular Diseases, First Affiliated Hospital, Guangxi Medical University, China;
2 Wuhan Mental Health center Tongji Medical College of Huazhong University of Science & Technology, China;
3 Cancer Center, Nanjing Drum Tower Hospital, Nanjing Medical University, China;.
Proposed Date: 10/01/2008 |
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CYP3A5 and Blood Pressure
Raymond Givens and Nobuyo Maeda (University of North Carolina at Chapel Hill)
Proposed Date: 11/30/2007 |
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Influence of CYP2C9, VKORC1 and environmental factors on patient response to warfarin
Andrea Jorgensen, Munir Pirmohamed, Catrin Tudur Smith, Paula Williamson (University of Liverpool)
Proposed Date: 11/12/2007 |
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Estrogen receptor alpha and risk factors for cardiovascular disease
Krista Casazza (University of Alabama at Birmingham)
Proposed Date: 12/11/2007 |
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Lipoprotein lipase gene polymorphisms and coronary heart disease
Gurdeep Sagoo et al. (Public Health Genetics Unit, Cambridge, UK) |
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Polymorphisms of the Angiotensin II Type 1 Receptor Gene and Hypertension
Amy Mottl (U of North Carolina, Chapel Hill) |
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Platelet IIIa Receptor Polymorphisms and Coronary Heart Disease
Chris O'Donnell and Brendan Everett (National Heart, Lung, and Blood Institute) |
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Interleukin-6 (IL-6) Polymorphisms and Cardiovascular Disease
Miryoung Lee (Wright State Univ) |
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KCNQ1 and Long QT Syndrome
Stephen Modell et al. (U. of Michigan) |
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Angiotensin-Converting Enzyme Gene/Coronary Artery Disease
Rongling Li, Elizabeth Ofili, Rebecca Din (MSM, Atlanta), Marta
Gwinn (CDC) |
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Factor V Leiden and Venous Thrombosis
A. Sonder (Saint Louis U.), W. Burke (U. of Washington), C. Hooper
(CDC) |
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Prothrombin G20210A Mutation/Venous Thromboembolism
N. Dowling (Emory U.), C. Hooper (CDC) |
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G-protein beta3 polymorphims and hypertension
Winfried Siffert (Institut für Pharmakologie, Essen, Germany) |
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The Peroxisome Proliferator-activated Receptor Gamma2 (PPARg2) Polymorphoism (Pro12Ala) and Type 2 Diabetes
Hebe Gouda, Julian Higgins (Cambridge Public health Genetics Unit, UK ) and Ann-Helen Harding, Manjinder Sandhu (Cambridge University Department of Public Health and
Primary Care) |
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Vitamin D receptor gene (VDR) and type 2 diabetes
Jan Yates, Julian Higgins (Cambridge Public health Genetics Unit, UK ) and Ann-Helen Harding, Manjinder Sandhu (Cambridge University Department of Public Health and Primary Care) |
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Vitamin D Receptor (VDR) Gene and Type 1 Diabetes
Ismailov Rovshan (Univ of Pittsburgh) |
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Hepatocyte Nuclear Factor-1a and Maturity Onset Diabetes of the Young Type III (HNF-1a and MODY3)
Roberta C. Wines (U of Washington), Karen Edwards (U of Washington) |
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The Genetics of Paget's Disease of Bone
Alberto Falchetti (University of Florence , Florence , Italy) |
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Steroid Hormone Receptor Gene Polymorphisms and Osteoporosis
Maria Luisa Brandi (Univ of Florence, Italy) |
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HFE gene and nonalcoholic fatty liver disease: a systematic review and meta-analysis
Ruben Hernaez, Edwina Yeung, Jeanne M. Clark, Kris V. Kowdley (§), Frederick L. Brancati, Wen Hong Linda Kao (Johns Hopkins University) and (§- Virginia Mason Medical Center)
Proposed Date: 11/28/2007 |
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Tumor Necrosis Factor (TNF) Promoter Polymorphisms and Hepatitis C Disease Progression, Outcome, and Response to Therapy
William McGuire (Univ of Dundee, United Kingdom) |
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Mannose-Binding Lectin and Susceptibility to Tuberculosis
Marie V. Downer, Chad McKee (Immunology Branch, NCID) |
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Genetic association of the T16189C mitochondrial DNA polymorphism and dilated cardiomyopathy: a HuGE Review and meta-analysis
Bongani M. Mayosi and Gasna Shabodien (Univ Cape Town, South Africa) |
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The Genomics of Cerebral Palsy – a HuGE Systematic Review
O’Callaghan ME, MacLennan AH, Haan E, Dekker, G for the South Australian Cerebral Palsy Research Group
Proposed Date: 08/05/2008 |
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Amyotrophic Lateral Sclerosis and SOD1 gene
Manuel Corato, Alberto Galli, Cristina Cereda, Andrea Baccarelli, and Mauro Ceroni (University of Pavia) |
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Interleukin-1 gene with Febrile Seizures and Temporal Lobe Epilepsy
Marcelo Kauffman (Ramos Mejia Hospital, Buenos Aires, Argentina) |
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HLA-DQ, HLA-DR alleles and risk for multiple sclerosis (MS)
Dhelia Williamson (Centers for Disease Control and Prevention) |
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Association of Cytokine and Cytokine Receptor Gene Polymorphisms with Alzheimer's Disease: gene- disease association review
John P.A. Ioannidis (U. of Ioannina School of Medicine, Ioannina, Greece) |
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FRDA1 Gene (Friedreich Ataxia)
A Kenneson (CDC), George Wilmot (Emory U.) |
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Alpha-Synuclein Gene/Parkinson's Disease
M. Farrer, K. Gwinn, J. Hardy (Mayo Clinic) |
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Parkinson's Disease and Monoamine Oxidase B (MAO-B) Genotype
Samir Kelada, Paola Costa-Mallen, Harvey Checkoway, Lucio Costa (Univ. of Washington) |
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Genetic Variation Associated with Preterm Birth
Krista Crider, Rebecca Buss, Nedra Whitehead (Centers for Disease Control and Prevention) |
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Polymorphisms of the Adiponectin Gene and Obesity
Diane Smelser |
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Glucocorticoid Receptor Polymorphisms and Obesity Risk: A HuGE Minireview
Roland Rosmond (Sahlgrenska U. Hospital, Sweden) |
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Serotonin transporter (5HTT) Gene polymorphisms and risk of depression
Simon Gilbody (University of York, UK)
Proposed Date: 2/6/2007
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A meta-analytic review of the association between MTHFR polymorphisms, and depression
Simon Gilbody (University of York, UK) |
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Cytokine gene polymorphisms and adverse outcomes in renal tranplantation
Ammarin Thakkinstian, Mark McEvoy, Steve Bowe, and John Attia
(University of Newcastle, Australia) |
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Genetics of Preeclampsia
Yves Giguere (Hôpital ST-François d'Assise, Quebec, Canada) |
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Complement factor H polymorphism and age-related macular degeneration
Ammarin Thakkinstian, Pearline Han, Mark McEvoy, Wayne Smith, John Attia (University of Newcastle, Australia) |
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Head and Neck
Marko Lens (Imperial College London, UK)
International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens |
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Y chromosome microdeletions in male infertility
Borut Peterlin (UMC Ljubljana, Slovenia) |