Centers for Disease Control and Prevention Centers for Disease Control and Prevention CDC Home Search CDC CDC Health Topics A-Z site search
National Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
Site Search
 

HugeNet™

Genomics and Health Weekly Update

Human Genome Epidemiology (HuGE) Articles
July 27, 2006
Volume 17, No. 4

Return to Weekly Update

Many of the news links published in our Weekly Update are temporary, and we cannot guarantee access to stories longer than one or two weeks after the Update is published. We suggest you contact the news source directly for reprints.

These articles report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests.



Gene Variant Frequency

Prevalence of HFE mutations in California newborns
Hoppe C, et al.
Pediatr Hematol Oncol 2006 Sep;23(6):507-16

 

Infectious and Parasitic Diseases

Red blood cell polymorphisms in relation to Plasmodium falciparum asymptomatic parasite densities and morbidity in Senegal
Migot-Nabias F, et al.
Microbes Infect 2006 Jun

Timing of adequate antibiotic therapy is more determinant of outcome than TNF and IL-10 polymorphisms in septic patients
Garnacho-Montero J, et al.
Crit Care 2006 Jul;10(4):R111

Gene Polymorphisms in CCR5, CCR2, CX3CR1, SDF-1 and RANTES in Exposed but Uninfected Partners of HIV-1 Infected Individuals in North India
Suresh P, et al.
J Clin Immunol 2006 Jul

Mannose-binding lectin in susceptibility and progression of HIV-1 infection in children
Dzwonek A, et al.
Antivir Ther 2006;11(4):499-505

The Effect of CYP2C19 Polymorphisms on H. pylori Eradication Rate in Dual and Triple First-Line PPI Therapies: A Meta-analysis
Padol S, et al.
Am J Gastroenterol 2006 Jul;101(7):1467-75

           

 

Neoplasms

The association of CYP2D6 *10 polymorphism with breast cancer risk and clinico-pathologic characteristics in Chinese women
Li H, et al.
Acta Oncol 2006;45(5):597-601

Association between ulcerative growth and hypoxia inducible factor-1alpha polymorphisms in colorectal cancer patients
Fransen K, et al.
Mol Carcinog 2006 Jul

Polymorphisms in DNA repair genes XPD and XRCC1 and p53 mutations in lung carcinomas of never-smokers
Gao WM, et al.
Mol Carcinog 2006 Jul

Potential application of GSTT1-null genotype in predicting toxicity associated to 5-fluouracil irinotecan and leucovorin regimen in advanced stage colorectal cancer patients
Romero RZ, et al.
Oncol Rep 2006 Sep;16(3):497-503

The effect of immunoglobulin V(H) gene mutation status and other prognostic factors on the incidence of major infections in patients with chronic lymphocytic leukemia
Francis S, et al.
Cancer 2006 Jul

Association of the polymorphisms of genes involved in androgen metabolism and signaling pathways with familial prostate cancer risk in a Japanese population
Okugi H, et al.
Cancer Detect Prev 2006 Jul

LOH rather than genotypes of TP53 codon 72 is associated with disease-free survival in primary breast cancer
Kyndi M, et al.
Acta Oncol 2006;45(5):602-9

Association between Manganese Superoxide Dismutase Promoter Gene Polymorphism and Breast Cancer Survival
Martin RC Md, et al.
Breast Cancer Res 2006 Jul;8(4):R45

Variants in estrogen metabolism and biosynthesis genes and urinary estrogen metabolites in women with a family history of breast cancer
Greenlee H, et al.
Breast Cancer Res Treat 2006 Jul

Low Frequency of CHEK2 Mutations in Familial Pancreatic Cancer
Bartsch DK, et al.
Fam Cancer 2006 Jul

Risk of Non-Hodgkin lymphoma (NHL) in relation to germline variation in DNA repair and related genes
Hill DA, et al.
Blood 2006 Jul

Inconsistent association between the STK15 F31I genetic polymorphism and breast cancer risk
Fletcher O, et al.
J Natl Cancer Inst 2006 Jul;98(14):1014-8

Association of T-cell regulatory gene polymorphisms with susceptibility to gastric mucosa-associated lymphoid tissue lymphoma
Cheng TY, et al.
J Clin Oncol 2006 Jul;24(21):3483-9

HLA and MICA associations with head and neck squamous cell carcinoma
Reinders J, et al.
Oral Oncol 2006 Jul

 

Endocrine, Nutritional and Metabolic Diseases

MHC2TA single nucleotide polymorphism and genetic risk for autoimmune adrenal insufficiency
Ghaderi M, et al.
J Clin Endocrinol Metab 2006 Jul

G1793A polymorphisms in the methyl- enetetrahydrofolate gene: Effect of folic acid on homocysteine levels
Soares Melo S, et al.
Mol Nutr Food Res 2006 Jul

Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects
Grarup N, et al.
Diabetologia 2006 Jul

Effect of polymorphisms of the MTHFR and APOE genes on susceptibility to diabetes and severity of diabetic retinopathy in Brazilian patients
Errera FI, et al.
Braz J Med Biol Res 2006 Jul;39(7):883-8

Preproghrelin Leu72Met variant contributes to overweight in middle-aged men of a Japanese large cohort
Kuzuya M, et al.
Int J Obes (Lond) 2006 Jul

Effect of SstI Polymorphism of the Apolipoprotein CIII Gene and Environmental Factors on Risks of Hypertriglyceridemia in Taiwan Aborigines
Huang MC, et al.
Circ J 2006 Aug;70(8):1030-6

Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: Studies in 6018 whites
Jensen DP, et al.
Mol Genet Metab 2006 Jul

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program
Florez JC, et al.
N Engl J Med 2006 Jul;355(3):241-50

 

Diseases of the Blood & Blood-Forming Organ Disorders

Identification of ADRA2A polymorphisms related to shear-mediated platelet function
Yabe M, et al.
Biochem Biophys Res Commun 2006 Jul

Patients of African ancestry with hemophagocytic lymphohistiocytosis share a common haplotype of PRF1 with a 50delT mutation
Lee SM, et al.
J Pediatr 2006 Jul;149(1):134-7

 

Mental Disorders

MAOA promoter polymorphism and attention deficit hyperactivity disorder (ADHD) in indian children
Das M, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Jul

           

Association study of seven polymorphisms in four serotonin receptor genes on suicide victims
Videtic A, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Jul

Analysis of ProDH, COMT and ZDHHC8 risk variants does not support individual or interactive effects on schizophrenia susceptibility
Glaser B, et al.
Schizophr Res 2006 Jul

Interleukin-1 Gene Complex in Schizophrenia: An Association Study*
Saiz PA, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Jul

Tryptophan hydroxylase 1 gene haplotypes modify the effect of a hostile childhood environment on adulthood harm avoidance
Keltikangas-Jarvinen L, et al.
Genes Brain Behav 2006 Jul

Gene for the serotonin transporter and ADHD: No association with two functional polymorphisms
Wigg KG, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Jul

Association study of the glycogen synthase kinase-3beta gene polymorphism with prophylactic lithium response in bipolar patients
Szczepankiewicz A, et al.
World J Biol Psychiatry 2006;7(3):158-61

No evidence for an association between the BDNF Val66Met polymorphism and schizophrenia or personality traits
Tochigi M, et al.
Schizophr Res 2006 Jul

Common variations in ALG9 are not associated with bipolar I disorder: a family-based study
Baysal BE, et al.
Behav Brain Funct 2006 Jul;2(1):25

Sleep and COMT Polymorphism in ADHD Children: Preliminary Actigraphic Data
Gruber R, et al.
J Am Acad Child Adolesc Psychiatry 2006 Aug;45(8):982-9

Association between suicide attempts in south Brazilian depressed patients with the serotonin transporter polymorphism
Segal J, et al.
Psychiatry Res 2006 Jul

 

Diseases of the Nervous System and Sense Organs

Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration
Despriet DD, et al.
JAMA 2006 Jul;296(3):301-9

Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans
Kim H, et al.
Mol Pain 2006 Jul;2(1):24

Gln192Arg polymorphism in paraoxonase 1 gene is associated with Alzheimer disease in a Chinese Han ethnic population
He XM, et al.
Chin Med J (Engl) 2006 Jul;119(14):1204-9

Functional polymorphisms in the mannan-binding lectin 2 gene: effect on MBL levels and otitis media
Wiertsema SP, et al.
J Allergy Clin Immunol 2006 Jun;117(6):1344-50

Polymorphisms and haplotypes in the C-reactive protein gene and risk of dementia
van Oijen M, et al.
Neurobiol Aging 2006 Jul

Exclusion of mutations in the PRNP, JPH3, TBP, ATN1, CREBBP, POU3F2 and FTL genes as a cause of disease in Portuguese patients with a Huntington-like phenotype
Costa MD, et al.
J Hum Genet 2006 Jul

Effect of the BDNF V166M polymorphism on working memory in healthy adolescents
Hansell NK, et al.
Genes Brain Behav 2006 Jul

Ethnic variation in AMD-associated complement factor H polymorphism p.Tyr402His
Grassi MA, et al.
Hum Mutat 2006 Jul

Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study
Leschziner G, et al.
Lancet Neurol 2006 Aug;5(8):668-76

Methylenetetrahydrofolate reductase gene polymorphisms c.677C/T and c.1298A/C are not associated with open angle glaucoma
Mabuchi F, et al.
Mol Vis 2006;12:735-9

 

Diseases of the Circulatory System

Apolipoprotein E polymorphism in relation to plasma lipid levels and other risk factors of atherosclerosis in two ethnic groups from Slovakia
Sivakova D, et al.
Coll Antropol 2006 Jun;30(2):387-94

A functional polymorphism in the glucocorticoid receptor gene and its relation to cardiovascular disease risk in familial hypercholesterolemia
Koeijvoets KC, et al.
J Clin Endocrinol Metab 2006 Jul

Role of Fibrinogen Levels and Factor XIII V34L Polymorphism in Thrombolytic Therapy in Stroke Patients
Gonzalez-Conejero R, et al.
Stroke 2006 Jul

 

Diseases of the Respiratory System

A Single Polymorphism in CCL1 Gene Predicts Acute Exacerbations in COPD
Takabatake N, et al.
Am J Respir Crit Care Med 2006 Jul

An association between asthma and TNF-308G/A polymorphism: meta-analysis
Aoki T, et al.
J Hum Genet 2006 Jul

 

Diseases of the Digestive System

Estrogen receptor gene polymorphisms and HBV-induced liver cirrhosis
Xie JP, et al.
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2006 Jun;31(3):379-82

Genetic susceptibility to ulcerative colitis in the Chinese Han ethnic population: association with TNF polymorphisms
Cao Q, et al.
Chin Med J (Engl) 2006 Jul;119(14):1198-203

A functional variant in the CD209 promoter is associated with DQ2-negative celiac disease in the Spanish population
Nunez C, et al.
World J Gastroenterol 2006 Jul;12(27):4397-400

Association Between Achalasia and Nitric Oxide Synthase Gene Polymorphisms
Mearin F, et al.
Am J Gastroenterol 2006 Jul

Genetic variants of RANTES are associated with serum RANTES level and protection for type 1 diabetes
Zhernakova A, et al.
Genes Immun 2006 Jul

 

Diseases of the Genitourinary System

Variants in the 5-Alpha-Reductase Type 1 and Type 2 Genes Are Associated with Polycystic Ovary Syndrome and the Severity of Hirsutism in Affected Women
Goodarzi MO, et al.
J Clin Endocrinol Metab 2006 Jul

Androgen receptor CAG polymorphism (Xq11-12) status and human spermatogenesis: A prospective analysis of infertile males and their offspring conceived by intracytoplasmic sperm injection
Katagiri Y, et al.
Int J Mol Med 2006 Sep;18(3):405-13

Association study of four polymorphisms in three folate-related enzyme genes with non-obstructive male infertility
Lee HC, et al.
Hum Reprod 2006 Jul

Ethnic distribution of estrogen receptor-alpha polymorphism is associated with a higher prevalence of uterine leiomyomas in black Americans
Al-Hendy A & Salama SA
Fertil Steril 2006 Jul

 

Complications of Pregnancy, Childbirth, and the Puerperium

Association study of IL-10 and IFN-gamma gene polymorphisms in Iranian women with preeclampsia
Kamali-Sarvestani E, et al.
J Reprod Immunol 2006 Jul

Prolylcarboxypeptidase gene, chronic hypertension, and risk of preeclampsia
Wang L, et al.
Am J Obstet Gynecol 2006 Jul;195(1):162-71

 

Diseases of the Musculoskeletal System and Connective Tissue

Relationship of collagen type I alpha 1 and alpha 2 gene polymorphisms with bone mineral density
Li DF, et al.
Nan Fang Yi Ke Da Xue Xue Bao 2006 Jul;26(7):981-3

Microsatellite typing for DRB1 alleles: application to the analysis of HLA associations with rheumatoid arthritis
Lee HS, et al.
Genes Immun 2006 Jul

HLA-DRB1alleles and osteoarthritis in a group of patients living in Liguria-Italy
Rovetta G, et al.
Minerva Med 2006 Jun;97(3):271-5

The positive effect of dietary vitamin D intake on bone mineral density in men is modulated by the polyadenosine repeat polymorphism of the vitamin D receptor
Michaelsson K, et al.
Bone 2006 Jul

Association of the FCRL3 gene with RA: a further example of population specificity?
Eyre S, et al.
Arthritis Res Ther 2006 Jul;8(4):R117

 

Congenital Anomalies

Single nucleotide polymorphism and haplotype in TBX1 gene of patients with contruncal defects: analysis of 130 cases
Han XM, et al.
Zhonghua Yi Xue Za Zhi 2006 Jun;86(22):1553-7

 

For more information on HuGE, please visit the HuGENet™ home page

To receive notification of this update by e-mail, please send the following message:
To: listserv@listserv.cdc.gov
Subject: (leave blank)
Message: subscribe genetics

The CDC Office of Genomics and Disease Prevention makes available the above information as a public service only.
Providing this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

Page last reviewed: June 8, 2007 (archived document)
Page last updated: November 2, 2007
Content Source: National Office of Public Health Genomics