Chemical Sampling Information
	Nitrogen dioxide
Quick Links General Description Exposure Limits Health Factors Monitoring Search    [use word(s)/phrase] Table of Contents By Name A B C D E F G H I J K L M N O P Q R S T U V W X Y Z By CAS Number General Description Synonyms: Diesel Exhaust Component; Dinitrogen tetroxide (N2O4); NO2; Nitrogen peroxide; Nitrogen tetroxide OSHA IMIS Code Number: 1903 Chemical Abstracts Service (CAS) Registry Number: 10102-44-0 NIOSH, Registry of Toxic Effects (RTECS) Identification Number: QW9800000 Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 1067 124 [27 KB, PDF] NIOSH Pocket Guide to Chemical Hazards, Nitrogen dioxide: chemical description, physical properties, potentially hazardous incompatibilities, and more Exposure Limits OSHA Permissible Exposure Limit (PEL) for General Industry: 29 CFR 1910.1000 Z-1 Table -- 5 ppm, 9 mg/m3 Ceiling OSHA Permissible Exposure Limit (PEL) for Construction Industry: 29 CFR 1926.55 Appendix A -- 5 ppm, 9 mg/m3 Ceiling OSHA Permissible Exposure Limit (PEL) for Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 5 ppm, 9 mg/m3 Ceiling American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 3 ppm, 5.6 mg/m3 TWA; 5 ppm, 9.4 mg/m3 STEL; Appendix A4 - Not Classifiable as a Human Carcinogen National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 1 ppm, 1.8 mg/m3 STEL Health Factors NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 20 ppm Potential symptoms: Irritation of eyes, nose, throat; cough, mucoid frothy sputum, decreased pulmonary function, chronic bronchitis, dyspnea (breathing difficulty); chest pain; pulmonary edema, cyanosis, tachypnea, tachycardia; eye, skin burns; dermatitis, frostbite (upon contact with liquid); INGES ACUTE: Burns in mouth, throat and stomach. EXPOS CHRONIC: Headache, weakness, loss of appetite, nausea, sores in nose and mouth, erosion of teeth; emphysema. Health Effects: Irritation-Eye, Nose, Throat, Skin---Marked (HE14) Lung edema or bronchiolitis obliterans (HE11); Dental erosion (HE3) Affected organs: Eyes, respiratory system, cardiovascular system Notes: Nitrogen dioxide may increase bronchoconstriction in asthmatics at concentrations as low as 0.1 ppm. It is a component of silo gas thought to cause the sometimes fatal "silo fillers' disease." Other potential exposures include frying foods with oils (e.g., traditional Chinese cooking) and exhausts from internal combustion equipment used to resurface the ice in indoor skating facilities. Date Last Revised: 06/29/2004 Literature Basis: NIOSH Pocket Guide to Chemical Hazards: Nitrogen dioxide. International Chemical Safety Cards (WHO/IPCS/ILO): Nitrogen dioxide. Douglas, W.W., Hepper, N.G. and Colby, T.V.: Silo-filler's disease. Mayo Clin. Proc. 64(3): 291-304, 1989. Elsayed, N.M.: Toxicity of nitrogen dioxide: an introduction. Toxicology 89(3): 161-174, 1994. Horvath, E.P., doPico, G.A., Barbee, R.A. and Dickie, H.A.: Nitrogen dioxide-induced pulmonary disease: five new cases and a review of the literature. J. Occup. Med. 20(2): 103-110, 1978. Lin, T.-S. and Huang, Y.-L.: Elevated exposure to nitrogen dioxide during food preparation: results from a cooking laboratory. Bull. Environ. Contam. Toxicol. 72(3): 535-541, 2004. Pelham, T.W., Holt, L.E. and Moss, M.A.: Exposure to carbon monoxide and nitrogen dioxide in enclosed ice arenas. Occup. Environ. Med. 59(4): 224-233, 2002. Pohanish, R.P. (editor): Nitrogen Dioxide. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1713-1716. Monitoring Methods used by OSHA Laboratory Sampling/Analytical Method: sampling media: Molecular Sieve (Water washed, Triethanolamine impregnated) maximum volume: 3 Liters   maximum flow rate: 0.2 L/min (STEL or Ceiling) current analytical method: Ion Chromatography; IC method reference: OSHA Analytical Method (OSHA ID-182) method classification: Fully Validated note: Submit as a separate sample. All Trademarks are the property of their respective owners. Accessibility Assistance: Contact the OSHA Directorate of Science, Technology and Medicine at 202-693-2300 for assistance accessing PDF materials.