NAME: 5-Fluorouracil
SYNONYM(s):
Adrucil; Efudex; Fluoroplex; 5-Fluoropyrimidine-2,4-dione;
Fluorouracil; FU; 5-FU
IMIS: F127
CAS: 51-21-8
NIOSH: RTECS YR0350000; 85639
DESCRIPTION:
Crystals from water or methanol-ether;
MW:
130.08
MOLFM:
C4H3FN2O2
Exposure Limits
Health Factors
IARC:
Group 3, not classifiable as to its carcinogenicity to humans
Monitoring
PRIMARY SAMPLING/ANALYTICAL METHOD (SLC1):
MEDIA:
OSHA Versatile Sampler (OVS-2) - 13 mm XAD-2 tube (270/140 mg sections, 20/60 mesh) with Glass Fiber Filter enclosed
ANL SOLVENT:
Methanol
MAX V:
200 Liters MAX F:
1.0 L/min
ANL 1:
High Performance Liquid Chromatography; HPLC/U.
REF:
2 (OSHA In-house File)
CLASS:
Partially Validated
COND:
Methanol extraction; HPLC; Zorbax NH2 column; 40% hexane, 10%
isopropanol, 50% methanol; 1.5 mL/min; 266 nm, 254 nm; RT 4.9 min;
DL 0.5ng/inj C/P YC 5/88
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