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Abstract
Grant Number: 5R01LM006789-02 Project Title: OPTIMIZED PROTEIN INFORMATICS
PI Information: Name Title RACKOVSKY, SHALOM R. shelly@camelot.mssm.edu ASSOCIATE PROFESSOR Abstract: DESCRIPTION (adapted from the Abstract): The processing of biomolecular sequence and structure data is central to bioinformatics. No attention, however, has been paid to the problem of the optimization of data processing, in order to minimize the loss of information in transformation of biomolecular data. The work embodied in this proposal is directed toward this question. We intend to study protein sequence and structure data processing with reference to the following goals. The optimization of sequence representation for a specified structure representation, in order to guarantee that the maximum possible amount of structural information is carried by the sequence representation. The optimization of structure representation for a specified sequence representation, in order to guarantee that the maximum amount of information is carried by the structure representation.
Public Health Relevance:
This Public Health Relevance is not available.Thesaurus Terms:
data management, informatics, method development, protein structure, proteomics
Institution: MOUNT SINAI SCHOOL OF MEDICINE OF NYU OF NEW YORK UNIVERSITY NEW YORK, NY 100296574 Fiscal Year: 2002 Department: BIOMATHEMATICAL SCIENCES Project Start: 15-FEB-2001 Project End: 14-FEB-2004 ICD: NATIONAL LIBRARY OF MEDICINE IRG: ZLM1