Also called: Also called: PSP, Richardson-Steele-Olszewski syndrome, Steele-Richardson-Olszewski syndrome
Progressive supranuclear palsy (PSP) is a rare brain disease. It affects brain cells that control the movement of your eyes. This leads to serious and permanent problems with balance and the way you walk. It usually occurs in middle-aged or elderly people. Symptoms are very different in each person, but may include personality changes, speech, vision and swallowing problems. Doctors sometimes confuse PSP with Parkinson's disease or Alzheimer's disease.
PSP has no cure and no effective treatments. Walking aids, special glasses and certain medicines might help somewhat. Although the disease gets worse over time, it isn't fatal on its own. However, PSP is dangerous because it increases your risk of pneumonia and choking from swallowing problems and injuries from falling.
National Institute of Neurological Disorders and Stroke
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Progressive Supranuclear Palsy
(National Institute of Neurological Disorders and Stroke) - http://www.ninds.nih.gov/disorders/psp/detail_psp.htm
Also available in Spanish http://espanol.ninds.nih.gov/trastornos/paralisis_supranuclear_progresiva.htm
- Progressive Supranuclear Palsy(Mayo Foundation for Medical Education and Research) - http://www.mayoclinic.com/print/progressive-supranuclear-palsy/DS00909/DSECTION=all&METHOD=print
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Progressive Supranuclear Palsy(National Institute of Neurological Disorders and Stroke) - Short Summary - http://www.ninds.nih.gov/disorders/psp/psp.htm
- Progressive Supranuclear Palsy(We Move) - http://www.wemove.org/psp/
- Treatments for Progressive Supranuclear Palsy(We Move) - http://www.wemove.org/psp/psp_tre.html
- Coping with PSP(Society for Progressive Supranuclear Palsy) - Large PDF file - http://www.psp.org/materials/coping_with_psp.pdf
- PSP Disease Management(Society for Progressive Supranuclear Palsy) - Large PDF file - http://www.psp.org/materials/disease_management.pdf
- Progressive Supranuclear Palsy: Frequently Asked Questions(Society for Progressive Supranuclear Palsy) - http://www.psp.org/page/faq
- PSP and Other Day-to-Day Issues(Society for Progressive Supranuclear Palsy) - Large PDF file - http://www.psp.org/materials/psp_other_day_to_day_issues.pdf
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ClinicalTrials.gov: Supranuclear Palsy, Progressive(National Institutes of Health) - http://clinicaltrials.gov/search/open/condition=%22Supranuclear+Palsy,+Progressive%22
- Article: Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a... - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=18464278&tool=MedlinePlus
- Article: Astrocytic tau pathology positively correlates with neurofibrillary tangle density in... - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=18427815&tool=MedlinePlus
- Article: Clinical outcomes of progressive supranuclear palsy and multiple system atrophy. - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=18385183&tool=MedlinePlus
- Progressive Supranuclear Palsy -- see more articles - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&term=supranuclear+palsy,progressive[majr]+AND+english[la]+AND+humans[mh]+NOT+(letter[pt]+OR+editorial[pt]+OR+case+reports[pt])&doptcmdl=summary&cmd_current=Limits&pmfilter_EDatLimit=last+1+Year&tool=MedlinePlus
- Progressive Supranuclear Palsy - http://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&binning-state=group%3d%3dMedical%20Encyclopedia&query=Progressive+Supranuclear+Palsy
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National Institute of Neurological Disorders and Stroke - http://www.ninds.nih.gov/
Also available in Spanish http://espanol.ninds.nih.gov/
- Society for Progressive Supranuclear Palsy - http://www.psp.org/
- We Move - http://www.wemove.org/
- Brain and Nerves - http://www.nlm.nih.gov/medlineplus/brainandnerves.html
The primary NIH organization for research on Progressive Supranuclear Palsy is the National Institute of Neurological Disorders and Stroke - http://www.ninds.nih.gov/