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Dose Finding Study Of CP-870,893, An Immune System Stimulating Antibody, In Combination With Paclitaxel And Carboplatin For Patients With Metastatic Solid Tumors

Basic Trial Information
Trial Description
     Summary
     Eligibility Criteria
Trial Contact Information

Basic Trial Information

Phase
Type
Status
Age
Sponsor
Protocol IDs

Phase I


Treatment


Active


18 to 85


Pharmaceutical / Industry


A5021004
NCT00607048

Trial Description

Summary

This is a dose-finding study; therefore, there is no hypothesis testing

Eligibility Criteria

Inclusion Criteria:

  • Patients with metastatic solid tumors, for whom carboplatin and paclitaxel are appropriate;
  • Patients >18 years of age;
  • Good performance status;
  • Adequate bone marrow and organ function

Exclusion Criteria:

  • Previous treatment with any other compound that targets CD40
  • Current or planned concurrent treatment with any anticancer agent;
  • Patients who have received bone marrow transplant;
  • History of autoimmune disorder
  • History (within the previous year) of heart failure or heart attack
  • Cancer-associated coagulation disorders

Trial Contact Information

Trial Lead Organizations/Sponsors

Pfizer Incorporated

Pfizer CT.gov Call CenterStudy Director

Pfizer Oncology Clinical Trial Information ServicePh: 1-877-369-9753
  Email: PfizerCancerTrials@emergingmed.com

Pfizer CT.gov Call CenterPh: 1-800-718-1021

Trial Sites

U.S.A.
Pennsylvania
  Philadelphia
 Pfizer Investigational Site
Texas
  San Antonio
 Pfizer Investigational Site

Link to the current ClinicalTrials.gov record.
NLM Identifer NCT00607048
Information obtained from ClinicalTrials.gov on October 01, 2008

Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.

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