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93.891 ALCOHOL RESEARCH CENTER GRANTS

FEDERAL AGENCY
NATIONAL INSTITUTES OF HEALTH, DEPARTMENT OF HEALTH AND HUMAN SERVICES

AUTHORIZATION
Public Health Service Act, as amended, Sections 301 and 464J; 42 U.S.C. 241 and 42 U.S.C. 285n-2.

OBJECTIVES
To provide long-term support for a concerted and multi-disciplinary research effort into the problems of alcohol use and alcoholism by coordinating the activities of investigators from biomedical, behavioral, and social science disciplines around a basic research theme. An alcohol research center is expected to realize its greater potential for contributing to the basic store of knowledge about alcohol and alcoholism and to become a significant regional and national resource.

TYPES OF ASSISTANCE
Project Grants.

USES AND USE RESTRICTIONS
Alcohol research center grant funds may be used for support of core resources including, for example, salaries of center personnel, services and facilities shared by center personnel, and program enrichment activities such as symposia. Support for individual components may include staff salaries, supplies, publication, travel and equipment. Funds may not be used for training, although the applicant is required to demonstrate an institutional training capacity related to alcohol. Funds may not be used for purchase of any land or the purchase, construction, preservation or repair of any building, and grantees must have sufficient laboratory facilities and reference services to carry out the grant. Support will be provided for up to 5 years (renewable for subsequent periods) to qualifying centers selected for funding. No annual grant may exceed $2,000,000 in total costs. The actual amount of support awarded will depend upon the appropriateness of the proposed center budget to the approved Center program, as well as the availability of funds.

Applicant Eligibility
State and local governments, any domestic (nonfederal) public or private nonprofit and for-profit institution may apply for a center grant. However, the proposed center must be affiliated with an institution, such as a university, medical center, or research center, that has the resources to sustain a long-term coordinated research program around a central theme related to problems of alcohol use and alcoholism. An applicant institution must demonstrate the ability to attract high quality scientists, from biomedical, behavioral, and social science disciplines, who are willing to make a long-term commitment to alcohol research. In addition, the applicant must assure that alcoholism related research and clinical training opportunities will be available.

Beneficiary Eligibility
Public and private nonprofit and for-profit organizations.

Credentials/Documentation
Costs will be determined in accordance with OMB Circular No. A-87 for State and local governments. For other grantees, costs will be determined in accordance with HHS Regulations 45 CFR Part 74, Subpart C, Section 74.27.

Preapplication Coordination
None. This program is excluded from coverage under E.O. 12372.

Application Procedure
The standard application forms, as furnished by PHS must be used by grant applicants. This program is subject to 45 CFR Part 92 for State and local governments and Circular No. A-110 for nonprofit organizations.

Award Procedure
Grants in support of approved applications are awarded directly to the applicant institution by the NIAAA.

Deadlines
Deadlines will be announced in specific Requests for Applications (RFA) to be published in the NIH Guide for Grants and Contracts. Contact Headquarters Office listed below for deadline dates.

Range of Approval/Disapproval Time
The time from receipt of application to final action is approximately 9 to 10 months.

Appeals
A principal investigator may appeal the substantive or procedural aspects of the review of his/her application to the staff of the Institute. A description of the NIH Peer Review Appeal procedures is available on the NIH home page www.nih.gov/grants/guide/1997/97.11.21/n2.html .

Renewals
Support is recommended for a specified project period of up to 5 years. Prior to termination of a project period, the grantee may apply for renewal of support for a new project period. An application for renewal is processed as a competing request.

Formula and Matching Requirements
None.

Length and Time Phasing of Assistance
The normal project period for an alcohol research center grant is 5 years. Grantees may apply for renewal of support on a competing basis. Within the project period, continuation applications must be submitted on a non-competing basis for each year of approved support. Payments will be made either on a Monthly Cash Request System or under an Electronic Transfer System. Necessary instructions for the appropriate type of payment will be issued shortly after an award is made.

Reports
Centers will be required to submit detailed annual progress reports (including substantive information about research results to date, status of ongoing research, research plans for the next year and any modifications in long-term research plans). Also, inventions reporting, financial status reports, final progress reports, and other reports are required to be filed in accordance with PHS policy.

Audits
Audits are to be carried out in accordance with the provisions set forth in 45 CFR Part 74, Subpart C, Section 74.26 and in OMB Circular No. A-133, as appropriate. In addition, grants and cooperative agreements are subject to inspection and audits by DHHS and other Federal officials. In accordance with the provisions of OMB Circular No. A-133, (Revised, June 24, 1997), "Audits of States, Local Governments, and Nonprofit Organizations," nonfederal entities that expend financial assistance of $300,000 or more in Federal Awards will have a single or a program-specific audit conducted for that year. Nonfederal entities that expend less than $300,000 a year in Federal awards are exempt from Federal audit requirements for the year, except as noted in Circular No. A-133.

Records
Records must be retained at least 3 years; records shall be retained beyond the 3-year period if audit findings have not been received.

Account Identification
75-0894-0-1-552.

Obligations
(Grants) FY 07 $27,276,000; FY 08 est $27,276,000; and FY 09 est not reported.

Range and Average of Financial Assistance
FY 07 $662,000 to $2,035,000; $1,685,000.

PROGRAM ACCOMPLISHMENTS
None.

REGULATIONS, GUIDELINES, AND LITERATURE
42 CFR Part 54a, Subpart E. Guidelines are included in application kits. PHS Grants Policy Statement, DHHS Publication No. (OASH) 94-50,000, (Rev.) April 1, 1994. Specific RFAs are published in the NIH Guide for Grants and Contracts.

Regional or Local Office
The Headquarters Office (National Institute on Alcohol Abuse and Alcoholism) is responsible for the administration of this program.

Headquarters Office
Program Contacts: Dr. Antonio Noronha, Director, Division of Neuroscience and Behavior: Telephone: (301) 443-7722. Dr. Ralph Hingson, Director, Division of Epidemiology and Prevention Research: (301) 443-1274. Dr. Mark Willenbring, Director, Division of Treatment and Recovery Research: (301) 443-1208. Dr. Samir Zakhari, Division of Metabolism and Health Effects: (301) 443-0799. National Institute on Alcohol Abuse and Alcoholism, NIH, Department of Health and Human Services, 5635 Fishers Lane, Bethesda, MD 20892-9304. Grants Management Contact: Judy Fox, Grants Management Officer, National Institute on Alcohol Abuse and Alcoholism, NIH, Department of Health and Human Services, 5635 Fishers Lane, Room 3023, Bethesda, MD 20892-9304. Telephone: (301) 443-4704. Use the same numbers for FTS.

Web Site Address
http://www.niaaa.nih.gov

RELATED PROGRAMS
93.271, Alcohol Research Career Development Awards for Scientists and Clinicians; 93.272, Alcohol National Research Service Awards for Research Training; 93.273, Alcohol Research Programs.

EXAMPLES OF FUNDED PROJECTS
Genetic approaches to neuropharmacology of ethanol, effects of alcohol on the central nervous system, the etiology and treatment of alcoholism, metabolism of alcohol and pathological effects, epidemiology of alcohol problems, environmental approaches to prevention, and translational neuroscience of alcoholism.

CRITERIA FOR SELECTING PROPOSALS
Scientific/technical merit, the feasibility of the research, alcoholism implications and relevance to NIAAA priorities and public health issues are all considerations in determining what projects will be funded.


General Services Administration
Office of Chief Acquisition Officer
Regulatory and Federal Assistance Division (VIR)