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93.271 ALCOHOL RESEARCH CAREER DEVELOPMENT AWARDS FOR SCIENTISTS AND CLINICIANS

(Research Career )

FEDERAL AGENCY
NATIONAL INSTITUTES OF HEALTH, DEPARTMENT OF HEALTH AND HUMAN SERVICES

AUTHORIZATION
Public Health Service Act, Title III, Section 301, Public Law 78-410, 42 U.S.C. 241, as amended.

OBJECTIVES
To provide support for increased research experience relating to the problems of alcohol abuse and alcoholism prevention, treatment, and rehabilitation; and to raise the level of competence and increase the number of individuals engaged in such research.

TYPES OF ASSISTANCE
Project Grants.

USES AND USE RESTRICTIONS
Mentored Research Scientist Development Awards (K01), Mentored Clinical Scientist Development Awards (K08), and Independent Scientist Awards (K02) provide support for individuals with research potential who need additional development and/or experience in a productive research environment. Mentored Patient-Oriented Research Career Development Award (K23) and Mid-career Investigator Award in Patient Oriented Research (K24) and Mentored Quantitative Research Career Development Award (K25) are also available. Senior Scientist Awards (K05) are also available to enable senior investigators to devote full-time to research. Academic Career Awards (K07) are also available for clinical faculty development. Awards are available for 5 years of salary support (up to 75 percent of the legislated maximum salary of $161,200) for the individual candidate, fringe benefits and 8 percent indirect costs. Specialized training costs and limited research costs are allowable under certain circumstances. Salary support may be supplemented by the sponsoring institution from nonfederal funds.

Applicant Eligibility
Mentored Research Scientist Development Awards, Mentored Clinical Scientist Development Awards, Independent Scientist Awards, Senior Scientist Awards, and Academic Career Awards for clinical faculty are made to appropriate research centers, medical schools, departments of psychiatry, non-medical academic departments, psychiatric hospitals or hospitals with psychiatric services, community mental health centers, biomedical research institutes, and departments of behavioral science on behalf of individuals who need the opportunity to realize research potentials. The individuals in all cases must be citizens or nationals of the United States or have been lawfully admitted for permanent residence. Individuals must qualify by scholastic degree and previous training and/or experience.

Beneficiary Eligibility
Public and private profit or nonprofit organizations.

Credentials/Documentation
Costs will be determined in accordance with OMB Circular No. A-87 for State and local governments. For-profit grantees' costs will be determined in accordance with Subpart 31.2 of the Federal Acquisition Regulations. For other grantees, costs will be determined in accordance with HHS Regulation 45 CFR Part 74, Subpart C, Section 74.27.

Preapplication Coordination
Not applicable. This program is excluded from coverage under E.O. 12372.

Application Procedure
The standard application forms as furnished by PHS must be used by applicants. Completed applications should be submitted to the Center for Scientific Review, National Institutes of Health, MD 20892. Completed applications are reviewed by nonfederal consultants and recommend for support on the basis of merit. This program is subject to the provisions of 45 CFR Part 92 and OMB Circular No. A-110, as appropriate.

Award Procedure
All NIAAA Research Career Development Awards for scientists and clinicians are recommended for approval by the National Advisory Council on Alcohol Abuse and Alcoholism and those approved for payment are awarded directly by NIAAA to the applicant institution.

Deadlines
February 1, June 1, and October 1.

Range of Approval/Disapproval Time
A range of 240 to 270 days from submission of the application.

Appeals
A principal investigator may appeal the substantive or procedural aspects of the review of his/her application to the staff of the Institute. A description of the NIH Peer Review Appeal procedures is available on the NIH home page www.nih.gov/grants/guide/1997/97.11.21/n2.html .

Renewals
Mentored Research Scientist Development Awards, Mentored Clinical Scientist Development Awards, Independent Scientist Awards, Senior Scientist Awards, Mentored Patient Oriented Research Career Development Awards, Mentored Quantitative Research Career Development Award, and Academic Career Awards are made for 5-year periods with renewal for Independent Scientist Awards and Senior Scientist Awards. Mid-career Investigator Awards in Patient-Oriented Research are renewable for one additional 5-year period if the candidate still meets the stated requirements.

Formula and Matching Requirements
None.

Length and Time Phasing of Assistance
Payment will be made either on a Monthly Cash Request System or under an Electronic Transfer System. Necessary instructions for the appropriate type of payment will be issued shortly after an award is made.

Reports
Reports must be submitted as follows: (1) Interim Progress Reports annually as part of continuation applications; (2) Annual financial status reports at termination of year of support; and (3) Final Invention Statement at end of support.

Audits
Audits are to be carried out in accordance with the provisions set forth in 45 CFR 74, Subpart C, Section 74.26. In accordance with the provisions of OMB Circular No. A-133 (Revised, June 24, 1997), "Audits of States, Local Governments, and Non-Profit Organizations," nonfederal entities that expend financial assistance of $300,000 or more in Federal awards will have a single or a program- specific audit conducted for that year. Nonfederal entities that expend less than $300,000 a year in Federal awards are exempt from Federal audit requirements for that year, except as noted in Circular No. A-133. In addition, grants and cooperative agreements are subject to inspection and audits by DHHS and other Federal government officials.

Records
Records must be retained for at least 3 years; records shall be retained beyond the 3-year period if audit findings have not been resolved.

Account Identification
75-0894-0-1-552.

Obligations
(Grants) FY 07 $11,781,000; FY 08 est $12,051,000; and FY 09 est not reported.

Range and Average of Financial Assistance
$92,000 to $259,000; $133,000.

PROGRAM ACCOMPLISHMENTS
None.

REGULATIONS, GUIDELINES, AND LITERATURE
42 CFR 52; Guidelines included in application kit; PHS Grants Policy Statement, DHHS Publication No. (OASH) 94-50,000, (Rev.) April 1, 1994. Specific program announcements are available electronically from the NIAAA World Wide Web Home Page on the Internet at http://www.niaaa.nih.gov or from the NIH Home Page under Institutes and Offices. Applicants should also obtain NIAAA additional information to the NIH Career Development Program Announcements (K AWARDS) NIH Guide, Volume 24, Number 26, July 21, 1995, which is also available on the NIAAA Home Page.

Regional or Local Office
None.

Headquarters Office
Program Contacts: Dr. Sam Zakhari, Director, Division of Metabolism and Health Effects. Telephone: (301) 443-0799. Dr. Mark Willenbring, Director, Division of Treatment and Recovery. Telephone: (301) 443-1208. Dr. Ralph Hingson, Director, Division of Epidemiology and Prevention Research: Telephone: (301) 443-1274. Dr. Antonio Noronha, Director, Division of Neuroscience and Behavior. Telephone: (301) 443- 7722. National Institute on Alcohol Abuse and Alcoholism, NIH, Department of Health and Human Services, 5635 Fishers Lane, MSC 9304, Bethesda, MD 20892-9304. Grants Management Contact: Ms. Judy Fox, Grants Management Officer. Telephone: (301) 443-4704. Use the same numbers for FTS.

Web Site Address
http://www.nih.gov

RELATED PROGRAMS
93.272, Alcohol National Research Service Awards for Research Training; 93.273, Alcohol Research Programs.

EXAMPLES OF FUNDED PROJECTS
(1) Organizational aspects of industrial alcohol programs; (2) antecedents and consequences of alcohol consumption patterns; (3) fatty acid synthesis alcohol-induced changes; and (4) mechanisms of alcohol-induced deficits in vision.

CRITERIA FOR SELECTING PROPOSALS
The following considerations are used in determining projects to be funded: (1) Evidence of the candidate's potential to develop and/or perform as an outstanding research scientist; (2) overall scientific and technical merit of the proposed research plans; (3) relevance to NIAAA priorities; (4) the potential contribution to the field of alcohol abuse and alcoholism; and (5) availability of funds.


General Services Administration
Office of Chief Acquisition Officer
Regulatory and Federal Assistance Division (VIR)