NAVAL AIR STATION PATUXENT RIVER
(a/k/a PATUXENT NAVAL AIR STATION
PATUXENT, ST. MARY'S COUNTY, MARYLAND
CONCLUSIONS
The consumption limit currently in effect at NAS Patuxent River for fish taken
from ponds on base is protective of all persons, even sensitive populations
including pregnant women, embryos, fetuses, lactating mothers, and breast-fed
neonates and infants.
RECOMMENDATION
ATSDR recommends continuation of the existing consumption limit Persons
consuming fish harvested from any of the six NAS Patuxent River ponds should
eat no more than two eight-ounce portions per month and 19 such meals per year
for no more than seven years, effectively a lifetime limit of 133 fish meals.
This would include men as well as women. Adverse reproductive effects in males
have been seen in animal studies from both PCBs and DDT, although at higher
concentrations than those for reproductive and developmental effects cited in
this consultation for females in animal studies.
REFERENCES
ATSDR, Final Public Health Assessment for Naval Air Station,
Patuxent River, August 18, 1997.
ATSDR, Final Public Health Assessment for Naval Air Station
PAtuxent River, August 18, 1997, p.11 and Appendix C.
ATSDR, Toxicological Profile for Polychlorinated Biphenyls
(Update) September 1997 p. 287.
Arnold DL, Mes J, Bryce F et all. 1990. A Pilot Study
on the Effects of Arcolor 1254 Ingestion by Rhesus and Cynomologus Monkeys
as a Model for Human Ingestion of PCBs, Food Chem Toxicol 28:847-857.
Arnold DL, Bryce F, Karpinski K et al. 1993. Toxicological
Consequences of Arcolor 1254 Ingestion by Female Rhesus (Macaca mulatta) Monkey,
Food Chem Toxicol 31: 799-824
ATSDR, Toxicological Profile for Polychlorinated Biphenyls
(Update) September 1997 p. 304.
Ibid. p. 84.
Schwartz PM, Jacobson SW, Fein G, et al. 1983. Lake Michigan
Fish Consumption as a Source of Polychlorinated Biphenyls in Human Cord Serum,
Maternal Serum and Milk, Am J Public Health, 73: 293.
ATSDR, Toxicological Profile for Polychlorinated Biphenyls
(Update) September 1997 p. 287.
Fein CG, Jacobson SW, Schwartz PM, et al. 1984. Prenatal
Exposure to Polychlorinated Biphenyls: Effects on Birth Size and Gestational
Age, J Pediatr, 105:315
Jacobson JL, Jacobson SW, Humphrey HEB. 1990. Effects of
In Utero Exposure to Polychlorinated Biphenyls and Related Contaminants
on Cognitive Functioning in Young Children, J Pediatr, 116: 38-45.
Jacobson JL and Jacobson SW. 1996. Intellectual Impairment
in Children Exposed to Polychlorinated Biphenyls in Utero, New England
J Med, 335: 783-789.
Humphrey, HEB, 1988. Chemical contaiminanats in the Great
Lakes: The Human Health Aspect. In: Evans MS, ed. Toxic Contaminants and Ecosystem
Health: A Great Lakes Focus. New York, NY: John Wiley and Sons, 153-165
Paneth N, 1991. Human Reproduction After Easting PCB-Contaiminated
Fish, Health Environ Digest. 5: 4.
Kimbrough RD, 1995 Critical Reviews in Toxicology, 25:
133-163.
ATSDR, Final Public Health Assessment for Navala Air Station
Patuxent River, August 18, 1997, p. 11.
ATSDR, Toxicological Profile for 4-4'-DDT, 4-4'-DDE, and
4-4'-DDD (Update) May 1994, p. 119.
Ibid. p. 95.
Ibid. p. 95.
Ibid. p. 32.
Leoni V, Fabiani L, Marinelli G, Et al. 1989. PCB and
Other Organochlorine Compunds in Blood of Women with or without Miscarriage:
A Hypothesis of Correlation. Ecotoxic Environ Safety 17: 1-11.
ATSDR, Toxicological Profile for 4-4'-DDT, 4-4'-DDE, and
4-4'-DDD (Update) May 1994, p. 119.
Ibid. p. 34.
Keplinger M, Deichmann W. Sala F. 1970. Effects of Combinations
of Pesticides on Reproduction in Mice. In: Deichmann W, ed. Pesticde Symposia.
6th-7th Int-Am Conf Toxicol Occup Med, Miami, FL, 125-138.
ATSDR, Toxicological Profile for 4-4'-DDT, 4-4'-DDE, and
4-4'-DDD (Update) May 1994, p. 35.
Ibid. p. 35-38.
Eriksson P, Nordberg A. 1986. The Effects of DDT, DDOH-Palmitic
Acid and Chlorinated Paraffin on Muscarinic Receptors and the Sodium-Dependent
Choline Uptake in the Central Nervous System of Immature Mice. Toxicol Appl
Pharmacol 85: 121-127.
Eriksson P, Archer T. DFrediksson A. 1990. Altered Behaviour
in Adult Mice Exposed to a Single Low Dose of DDT and its Fatty Acide Conjungate
as Neonates. Brain Res 514: 141-142.
Eriksson P, Nilsson-Hakansson L, Nordberg A, et al. 1990.
Neonatal Exposure to DDT and its Fatty Acide Conjungate: Effects on Cholinergic
and Behavorial Variables in the Adult Mouse. Neuro Toxicol 11: 345-354.
