Submission of documents for an update/renewal to the registration of your organization (IORG) and institutional review board/independent ethics committee(s) [IRB/IEC(s)] using this electronic submission system will expedite processing by OHRP.

This area should ONLY be used for UPDATING/RENEWING an OHRP-registered IORG-IRB/IEC.

A registered IORG-IRB/IEC(s) is effective for 3 years; however, when information changes on the registration, an update/renewal should be submitted to OHRP.

Using this web page you can electronically submit an update/renewal to an OHRP-registered IORG-IRB/IEC(s). We recommend that you print out and have available the instructions for updating/renewing either a domestic (U.S.) or international (non-U.S.) IORG-IRB/IEC(s) at http://www.hhs.gov/ohrp/humansubjects/assurance/renwirb.htm.

Additional instructions for electronic submission of an update/renewal to your institution's IORG-IRB/IEC(s) registration are provided below:

1) You must have an e-mail address in order to use the electronic submission process. Additionally, you must know the LAST NAME of the Head Official and an IRB Chairperson, as well as the organization number (IORG), associated with your institution's IORG-IRB/IEC registration. You will be guided through the electronic submission process at the bottom of the screen.

2) After obtaining your submission number, as outlined below, you will be able to make changes to the registration of your IORG-IRB/IEC(s). All data currently on file with OHRP will appear in the various fields. However, if this is the first time that your organization has used the electronic submission system to update/renew the registration, you will have to enter the membership roster(s).

3) In addition to the changes you are making, you must ensure that ALL information in the IORG-IRB/IEC(s) registration record is accurate and complete before you "Submit" the update/renewal.

4) You will need to be sure all required (*) fields are completed.

5) Once you have entered or changed information on each screen and proofread all data fields, click on the "Save and Continue" button to move to the next section.

6) You may use the sidebar in the left margin of the screen for quickly moving from section to section of the IORG-IRB/IEC(s) registration form. However, please be aware that if you have not saved information on a page before going to another page, you will lose the information you entered on the last screen.

7) Once all entries are made, please proofread all fields of the IORG-IRB/IEC(s) registration form and roster(s) to ensure the accuracy of the data and click "Submit." If you left any required fields blank, you will be prompted to correct those errors. If not, you will be prompted to print a copy of your submission for your record.

8) Once you "Submit" the electronic update/renewal to your IORG-IRB/IEC(s), there is nothing else for you to do. OHRP will receive your electronic request and process it as soon as possible.

NOTE: You may begin entering information for an electronic submission and then find you are not ready to submit it to OHRP for review. In this case, you may save the data entered and return at a later time to complete the submission. Be sure you have recorded your submission number for later use.

There is no need to fax or mail anything when submitting IORG-IRB/IEC(s) documents electronically.

You may track receipt of your document at http://www.hhs.gov/ohrp/humansubjects/assurance/rlog.htm. All registered IORG-IRB/IEC(s) may be found at http://ohrp.cit.nih.gov/search/asearch.asp#ASUR.

With the electronic submission process, the submitter, the IRB/IEC Chair(s), and the IORG-IRB/IEC Head Official will be notified by e-mail as soon as OHRP has processed your submission. Of course, this is dependent upon e-mail addresses being provided for each of these individuals.

NOTE: YOU MUST REQUEST A SUBMISSION NUMBER FOR EACH SEPARATE ELECTRONIC IORG/IRB REGISTRATION YOU SEND TO OHRP. THE SUBMISSION NUMBER IS ONLY GOOD UNTIL OHRP PROCESSES THE IORG/IRB REGISTRATION ASSOCIATED WITH THAT SUBMISSION. AFTER PROCESSING OF AN ELECTRONICALLY SUBMITTED IORG/IRB, YOU MUST REQUEST A NEW SUBMISSION NUMBER FOR SUBSEQUENT ELECTRONIC UPDATES/RENEWALS . ALSO, PLEASE DO NOT ATTEMPT TO UPDATE/RENEW AN IORG/IRB REGISTRATION WHEN THERE IS ALREADY AN ELECTRONIC RECORD BEING PROCESSED BY OHRP. THE CHANGES YOU REQUEST WITH EACH ELECTRONIC SUBMISSION ARE NOT TRANSFERRED TO OHRP'S DATABASE UNTIL THE IORG/IRB REGISTRATION HAS BEEN PROCESSED. WHEN THE IORG/IRB REGISTRATION IS PROCESSED, YOU WILL RECEIVE AN E-MAIL NOTIFICATION.