Board of Scientific Counselors

Scientific Director’s Preface

Cell Biology and Metabolism Branch
Protein Sorting in the Endosomal-Lysosomal System: Juan Bonifacino
Regulation of Secretory and Membrane Protein Biogenesis: Ramanujan Hegde
Cell Cycle Regulation in Ovarian Cysts: Mary Lilly
Regulation of Membrane Dyamics and Protein Transport by the Sec7 Domain Guanine Nucleotide Exchange Factors: Catherine Jackson
Regulatory RNAs and Microbial Response to Oxidative Stress: Gisela Storz
Dynamics of Secretory Membrane Trafficking, Sorting and Compartmentalization: Jennifer Lippincott-Schwartz
Regulation of Intracellular Iron Metabolism: Tracey Rouault

Developmental Endocrinology Branch
Gender-Specific Brain and Reproductive Development: Carolyn Bondy
Molecular Genetics of Adrenocortical Tumors and Related Disorders: Constantine Stratakis

Regulation of Skeletal Growth: Jeffrey Baron
Neuroendocrinology of Stress: Greti Aguilera
Growth and Obesity: Jack Yanovski
The Menstrual Cycle and Human Reproduction: Lawrence Nelson

Endocrinology and Reproduction Research Branch
Phosphoinositide-Calcium Signaling in Cell Regulation: Tamás Balla
Peptide Hormone Receptors and Signal Transduction: Kevin Catt
Gonadal Receptors and Mechanism of Action of Peptide Hormones in Steroidogenic Cells: Maria Dufau
Calcium Signalling and Calcium-Controlled Cellular Functions: Stanko Stojilkovic
Structure and Function of Peptide and Protein Hormones: Hao-Chia Chen
Signal Transduction In Synaptic Transmission: Kuo-Ping Huang
The Biotransformation of Endobiotics bv Sulfonation: Charles Strott

Heritable Disorders Branch
Connective Tissue Disorders: Joan Marini
Molecular Biology, Regulation, and Biochemistry of UDP-Glucuronosyltransferase Isozymes: Ida Owens
Inborn Errors of Metabolism: William Gahl
Heritable Neurodegenerative and Inflammatory/Autoimmune Disorders: Anil Mukherjee
Molecular Biology of Dysmorphology: Forbes Porter
Molecular Genetics of Heritable Human Disorders: Janice Chou

Laboratory of Cellular and Molecular Biophysics
Membrane Remodeling During Pathogenesis and the Mechanism of Exocytosis: Joshua Zimmerberg
Lateral Interactions between Adjacent Fusion Proteins: the Case of Influenza Virus Hemagglutinin: Leonid Chernomordik
Advances in the Methodology of Electrophoretic Separations: Andreas Chrambach
Applications of Mass Spectrometry to Biophysics, Biochemistry and Medicine: Alfred Yergey
Interactions of Human Pathogens in Human Lymphoid Tissue: Leonid Margolis

Laboratory of Cellular and Molecular Neurophysiology
Structure and Function of Glutamate Receptors: Mark Mayer

Laboratory of Cellular and Synaptic Neurophysiology
Hippocampal Interneurons and Their Role in Controlling Excitability: Chris Mcbain
Potassium Channels and Dendritic function in Hippocampal Pyramidal Neurons: Dax Hoffman
Regulation of Neuronal Gene Expression by Action Potentials: Douglas Fields
Neurotrophic Regulation of Synapse Development and Plasticity: Bai Lu
Second Messenger Systems in Glia and Pineal Cells: James Russell
Olfactory Coding by Ensembles of Neurons: Mark Stopfer

Laboratory of Clinical Genomics
Bridging the Gap between Monogenic Traits and Complex Inherited Disorders of Childhood: Stephen Kaler
Developmental Genomics: Owen Rennert


Laboratory of Comparative Ethology
Genetic and Environmental Determinants of Primate Biobehavioral Development: Stephen Suomi

Child and Family Development in the First Two Decades of Life: Marc Bornstein
Child Development in Context: Michael Lamb
Mechanisms Regulating Auditory Communication and Social Behavior in Primates and other Mammals: John Newman


Laboratory of Developmental and Molecular Immunity
Vaccines Against Human Pathogenic Bacteria: John Robbins
Human Immune Response to Polysaccharide-Protein Conjugate Vaccines: Rachel Schneerson

Laboratory of Developmental Neurobiology
Developmental Regulation of Neuronal and Muscle Plasticity: Andres Buonanno
Tetanus and Botulinum Neurotoxins and Neuronal Cell Biology: Elaine Neale
Mechanisms of Neurodevelopment in Health and Disease: Phillip Nelson
Neuropeptide-Mediated Regulation of Development: Douglas Brenneman
Biological Rhythms: The Pineal Gland: David Klein
Protein Trafficking and Secretory Granule Biogenesis in Neuroendocrine Cells: Peng Loh

Laboratory of Gene Regulation and Development
Transcriptional and Translational Control Mechanisms in Nutrient Regulation of Gene Expression: Alan Hinnebusch
Epigenetic Gene Silencing: Rohinton Kamakaka
Molecular Mechanism of Neuronal Connectivity: Chi-Hon Lee
Mitotic Regulation in Higher Eukaryotes by Ran and SUMO-1: Mary Dasso
Molecular Genetics of Retrotransposons: Henry Levin
Mechanism and Regulation of Eukaryotic Protein Synthesis: Thomas Dever
Molecular Mechanism of Frog Metamorphosis: Yun-Bo Shi
Control of Chromosome Transmission Fidelity by the SMC-Based Protein Complexes: Alexander Strunnikov

Laboratory of Integrative and Medical Biophysics
Cell Biophysics: Ralph Nossal
Medical Biophysics: Robert Bonner
Applications of Photon Migration to Tissue Tomography and Spectroscopy: Amir Gandjbakhche
Tissue Biophysics and Biomimetics: Peter Basser

Laboratory of Mammalian Genes and Development
Genes that Fashion the Mouse Embryo: Heiner Westphal
Signals Regulating T Cell Development: Paul Love
Molecular Genetics of an Imprinted Gene Cluster on Mouse Distal Chromosome 7: Karl Pfeifer

Laboratory of Molecular Genetics
Molecular Genetics of Embryogenesis in Xenopus and Zebrafish: Igor Dawid
Patterning Neurogenesis in the Zebrafish Embryo: Ajay Chitnis
Control of Gene Expression During Development: Judith Kassis
Regulation of Homeotic Genes in Drosophila: James Kennison
Integrative Control of Macromolecular Synthesis: Michael Cashel
Molecular Genetics of Mammlian Retrovirus Replication: Judith Levin
Physiological, Biochemical, and Molecular Genetic Events of Recognition and Resolution of RNA-DNA Hybrids: Robert Crouch
Control of Ectodermal Development in Xenopus: Thomas Sargent
Organogenesis of the Zebrafish Vasculature: Brant Weinstein
Control of Gene Expression in Prokaryotes: Robert Weisberg

Laboratory of Molecular Growth Regulation
Chromatin-Based Epigenetic Structures in the Control of Cell Differentiation and Proliferation: Bruce Howard
Developmental Gene Regulation of the Immune System: Keiko Ozato
Regulation of DNA Replication and Gene Expression During Animal Development: Melvin DePamphilis
Mechanisms of Eukaryotic RNA Expression and Functions of the Human La Antigen: Richard Maraia

The Laboratory of Physical and Structural Biology
Physical Forces Organizing Biomolecules: Adrian Parsegian
Intermolecular Forces, Recognition, and Dynamics: Donald Rau
Biophysics of Large Membrane Channels: Sergey Bezrukov

Pediatric and Reproductive Endocrinology Branch
The Hypothalamic-Pituitary-Adrenal Axis: Its Endocrine Disorders and Its Interactions with the Immune System: George Chrousos
Diagnosis, Pathophysiology, and Molecular Biology of Neuroendocrine Tumors: Karel Pacak
The Physiology of Hypercortisolism and the Endometrium: Lynnette Nieman
Reproductive Endocrinology and Infertility: James Segars

Perinatology Research Branch
Pathophysiology of Premature Labor and Complications of Prematurity and Prenatal Diagnosis of Congenital Anomalies: Roberto Romero

Physical Disabilities Branch
Advanced Technologies for Rehabilitation Research: Steven Stanhope

Section on DNA Replication, Repair and Mutagenesis
Studies on DNA Replication, Repair and Mutagenesis in Eukaryotic and Prokaryotic Cells: Roger Woodgate

Unit on Molecular Forces and Structure
Physical Principles of Biomolecular Recognition, Self-Assembly, and Regulation: Sergey Leikin