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Vaccine Therapy for Multiple Myeloma Utilizing Idiotype-Pulsed Allogeneic Dendritic Cells
Basic Trial Information
Summary Patients with Multiple myeloma who have undergone non-myeloablative allogeneic stem cell transplant will receive 6 vaccinations of donor derived dendritic cells combined with specific protein produced by multiple myeloma. Further Study Information To evaluate feasibility and safety of vaccination with allogeneic idiotype-pulsed dendritic cells following mixed chimeric allogeneic transplantation for multiple myeloma. Eligibility Criteria Inclusion Criteria:1. For specimen collection and idiotype protein development:
2. For Vaccination:
Donor Inclusion Criteria (allodonor is the same donor used for non-myeloablative transplant)
Exclusion Criteria:1. For specimen collection and idiotype protein development:
2. For Vaccination:
1. Mycophenylate Mofetil (MMF)- no greater than 1000mg twice a day 2. Prednisone- no greater than .5mg/kg/day 3. Cyclosporine- no greater than 300mg/day 4. Tacrolimis (FK506)- no greater than 4mg/day Trial Lead Organizations/Sponsors Stanford Cancer Center National Cancer Institute
Link to the current ClinicalTrials.gov record. Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain
the same text. Minor
changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and
contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should
be directed to ClinicalTrials.gov. Back to Top |
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