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Histoplasma skin test

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Illustrations

Aspergillus antigen skin test
Aspergillus antigen skin test

Definition    Return to top

Histoplasma skin test is a method to check if you have been exposed to a fungus called Histoplasma capsulatum. The fungus causes an infection called histoplasmosis.

How the Test is Performed    Return to top

The health care provider will clean an area with hair, usually the forearm. An allergen is injected just below the cleaned skin surface. The injection site is checked at 24 hours and at 48 hours for signs of a reaction. Occasionally, the reaction may not appear until the fourth day.

How to Prepare for the Test    Return to top

No special preparation is necessary for this test.

How the Test Will Feel    Return to top

There will be a brief sting as a needle is inserted just below the skin surface.

Why the Test is Performed    Return to top

This test is used to determine if a person has been exposed to the fungus that causes histoplasmosis.

Normal Results    Return to top

No reaction (inflammation) at the site of the test is normal. Of note, the skin test can sometimes make histoplasmosis antibody tests turn positive.

What Abnormal Results Mean    Return to top

A reaction means the person has been exposed to the histoplasmosis fungus.

Risks    Return to top

There is a slight risk of anaphylactic shock (a severe reaction).

Considerations    Return to top

This test is rarely used today. It has been replaced by a variety of blood tests.

Update Date: 8/16/2007

Updated by: Arnold L. Lentnek, MD, Division of Infectious Disease, Kennestone Hospital, Marietta, GA. Review provided by VeriMed Healthcare Network.

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