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Ceruloplasmin

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Definition   

Ceruloplasmin is a test that measures the amount of ceruloplasmin (a copper-containing protein) in blood serum.

How the Test is Performed   

Blood is drawn from a vein, usually from the inside of the elbow or the back of the hand. The puncture site is cleaned with antiseptic. An elastic band is placed around the upper arm to apply pressure and cause the vein to swell with blood.

A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. During the procedure, the band is removed to restore circulation. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

In infants or young children, the area is cleansed with antiseptic and punctured with a sharp needle or a lancet. The blood may be collected in a pipette (small glass tube), on a slide, onto a test strip, or into a small container. A bandage may be applied to the puncture site if there is any bleeding.

How to Prepare for the Test   

No fasting or other preparation is usually needed.

How the Test Will Feel   

When the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.

Why the Test is Performed   

This test may be performed when disorders of copper metabolism or storage are suspected. Ceruloplasmin is the major copper-containing protein in plasma.

What Abnormal Results Mean   

Lower-than-normal ceruloplasmin levels may indicate:

Greater-than-normal ceruloplasmin levels may indicate:

Risks   

Considerations   

Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

Update Date: 1/22/2007

Updated by: Benjamin W. Van Voorhees, MD, MPH, Assistant Professor of Medicine and Pediatrics, The University of Chicago, Chicago, IL. Review provided by VeriMed Healthcare Network.

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