-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 HXjjWNJ8vPct6bfQAvMElQ7uJivg8Y5LHaRC8HPBphG+DhFZYTtmofSMTO97Ue3t
 9+vuf+9rKHT4NuDlV4/t9A==

<SEC-DOCUMENT>0001170918-08-000122.txt : 20080306
<SEC-HEADER>0001170918-08-000122.hdr.sgml : 20080306
<ACCEPTANCE-DATETIME>20080306174400
ACCESSION NUMBER:		0001170918-08-000122
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080304
FILED AS OF DATE:		20080306
DATE AS OF CHANGE:		20080306

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Yi John U
		CENTRAL INDEX KEY:			0001343621

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-11181
		FILM NUMBER:		08672131

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		818-709-1244

	MAIL ADDRESS:	
		STREET 1:		29365 QUEENS WAY
		CITY:			AGOURA HILLS
		STATE:			CA
		ZIP:			91301

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			IRIS INTERNATIONAL INC
		CENTRAL INDEX KEY:			0000319240
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				942579751
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		9162 ETON AVE
		CITY:			CHATSWORTH
		STATE:			CA
		ZIP:			91311
		BUSINESS PHONE:		8187091244

	MAIL ADDRESS:	
		STREET 1:		9162 ETON AVENUE
		CITY:			CHATSWORTH
		STATE:			CA
		ZIP:			91311

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	INTERNATIONAL REMOTE IMAGING SYSTEMS INC /DE/
		DATE OF NAME CHANGE:	19920703
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>sam08-045_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-03-04</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000319240</issuerCik>
        <issuerName>IRIS INTERNATIONAL INC</issuerName>
        <issuerTradingSymbol>IRIS</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001343621</rptOwnerCik>
            <rptOwnerName>Yi John U</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O IRIS INTERNATIONAL, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>9172 ETON AVENUE</rptOwnerStreet2>
            <rptOwnerCity>CHATSWORTH</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>91311</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Corp. V.P., Operations</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2008-03-04</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>3798</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>54664</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Option (Right to Buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>11.65</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2008-03-04</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>29167</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2013-03-04</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>29167</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>29167</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Vests 25% on March 4, 2009 and thereafter 6.25% will vest in 12 equal quarterly installments with the first such installment
 vesting on June 30, 2009.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ John U. Yi</signatureName>
        <signatureDate>2008-03-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----