Vaccines and Preventable Diseases:
Current Vaccine Shortages & Delays
Last Updated September 3, 2008
On this page:
This web page contains the latest national information about vaccine supplies and provides guidance to healthcare providers who are facing vaccine shortages or delays.
On June 30, CDC's Travelers' Health web section updated its yellow fever vaccine supply statement. July 3
On August 29, CDC's Rabies site updated its status on the rabies vaccine supply. Sept. 3
(Vaccines are listed in order used for the Childhood and Adolescent Immunization Schedule.)
|National Vaccine Supply Shortages|
Temporary Change From Routine Recommendation
|Diphtheria, Tetanus, & Pertussis (DTaP and Tdap)||No|
|Haemophilus influenzae type B (Hib)||See note 1||
Flyer: What to do when giving the Hib vaccine during shortage (PDF 523KB) or (text-only ) Mar 3, 2008
See MMWR on the recall and interim recommendations Dec 19, 2007
See Q&A on Hib vaccine supply & recall and guidance for providers and patients (.DOC 61 KB) Dec 12, 2007
|Pneumococcal Conjugated (PCV)||No|
|Pneumococcal Polysaccharide (PPV)||No|
|Inactivated Polio (IPV)||No|
|Measles, Mumps, & Rubella (MMR)||No|
Current information about influenza, see www.cdc.gov/flu
|Varicella/Zoster||See note 2||
No change in Routine Recommendation. Zoster vaccine is available for ordering; however, the manufacturer is experiencing shipping delays. July 11
|Hepatitis A||See note 3||
No change in Routine Recommendation.
|Conjugated Meningococcal (MCV4)||No|
|Human Papillomavirus (HPV)||No|
*Note: Only those vaccines included on the recommended childhood and adolescent immunization schedule are included in this update.
Note1: Merck & Co., Inc. has initiated a voluntary recall in the United States for 10 lots of PedvaxHIB® (Haemophilus Influenzae type b Conjugate Vaccine) and two lots of COMVAX® (Haemophilus Influenzae type b Conjugate and Hepatitis B Vaccine). CDC has implemented interim recommendations for use of H. Influenzae type b Conjugate vaccines. CDC is working closely with the alternative manufacturer of Hib Vaccine (sanofi pasteur) to evaluate and ensure vaccine supply. Specific updates will be provided as soon as they are available. Merck is making every effort to restore its HIB-containing vaccines to full availability as soon as possible. At this time, it is estimated that these vaccines will be available again in fourth quarter 2008.
Note2: Merck has obtained FDA approval for resumption of manufacturing of Varicella Zoster Virus (VZV) bulk. VZV bulk is used to manufacture varicella vaccine, MMR-V vaccine, and zoster vaccine. There is adequate supply of Varivax® (varicella vaccine) to fully implement the recommended 2-dose immunization schedule for all age groups, including catch-up. ProQuad® (MMR-V) is currently unavailable. Zostavax® (zoster vaccine) is available for ordering, however, the manufacturer is experiencing shipping delays. Merck vaccine supply status updates including specific shipping status information for zoster vaccine is updated weekly and may be found at www.merckvaccines.com (exit site). July 11
Note3: Merck & Co., Inc., is experiencing production delays and has temporarily discontinued accepting orders for Pediatric and Adult hepatitis A vaccine (Pediatric & Adult VAQTA®). Based on current information, it is estimated that Pediatric VAQTA® will be available in fourth quarter 2008 and Adult VAQTA® in first quarter 2009. GSK production and supply of their Pediatric and Adult hepatitis A vaccine (Pediatric & Adult Havrix®) and their Adult hepatitis A/hepatitis B combination vaccine (Twinrix®) are currently in good supply to meet demand.
In the United States shortages of many vaccines in the recommended childhood immunization schedule occurred in the past. Some of these shortages were widespread while others were localized. Reasons for these shortages were multi-factorial and included companies leaving the vaccine market, manufacturing or production problems, and insufficient stockpiles. Consequently, some shortages were only specific to one manufacturer.
Shortages of several of these vaccines necessitated temporary changes in recommendations for their use. During that period, summary information about the shortages including projected duration and recommendations for temporary changes in the childhood immunization schedule were provided.
Questions including those dealing with changes in child care and school requirements necessitated by vaccine supply problems when they occur can be answered by
State Health Department immunization programs at www.cdc.gov/mmwr/international/relres.html
General immunization questions can be answered by
The CDC Contact Center at 1-800-CDC-INFO
(1-800-232-4636) English and Español
How often will this information be updated?
This page on the NCIRD web site www.cdc.gov/vaccines/vac-gen/shortages/ is updated as needed to provide public information on vaccine shortages and/or delays.
The FDA's web page on Biological Product Shortages www.fda.gov/cber/shortage/shortage.htm (exit) provides additional information regarding regulatory issues related to vaccine supply.
AAFP - American Academy of Family Physicians
AAP - American Academy of Pediatrics
ACIP - Advisory Committee on Immunization Practices
CDC - Centers for Disease Control and Prevention
FDA - Food and Drug Administration
GAO - United States General Accounting Office
MMWR - Morbidity and Mortality Weekly Report
NCIRD - National Center for Immunization and Respiratory Diseases
TTY - teletypewriter
- Status of Licensure and Recommendations for New Vaccines (exit)
- ACIP Provisional Vaccine Recommendations
- Influenza Vaccination Recommendations
- Childhood & Adolescent Immunization Schedules
- Adult Immunization Schedule
- Archive: Vaccine shortages in the past
Information about vaccines shortages and delays in past years
- FAQs on 2002 Vaccine Shortages
- PCV7 (Prevnar®) Recommendation Suspension Q&A (3/1/2004)
- PCV7 (Prevnar®) Recommendation Reinstatement Q&A (7/8/2004)
- Pneumococcal Availability (2001, 2002)
- Pneumococcal & DTaP Revised Recommendations (2001)
- Updated Recommendations for PCV7 (3/1/2004)
- Vaccine Shortages in the Spotlight (2001-2005)
- Varicella Recommendations (2002)
Non-CDC Link Disclaimer: Links to non-Federal organizations found at this site are provided solely as a service to our users. These links do not constitute an endorsement of these organizations or their programs by CDC or the Federal Government, and none should be inferred. The CDC is not responsible for the content of the individual organization web pages found at these links.
Content last reviewed on April 24, 2008
Content Source: National Center for Immunization and Respiratory Diseases