Phase II Randomized Study of Erlotinib With or Without Carboplatin and Paclitaxel in Patients With Chemotherapy-Naïve Select Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Final eligibility for a clinical trial is determined by the health professionals conducting the trial.
Patients will be randomly assigned (have an equal chance of being placed) to one of two treatment groups.
Patients in group one will receive erlotinib by mouth once a day. Treatment may continue for as long as benefit is shown.
Patients in group two will receive erlotinib by mouth once a day for as long as benefit is shown. They will also receive a 1- to 3-hour infusion of paclitaxel and an infusion of carboplatin once in week 1. Treatment with paclitaxel and carboplatin may repeat every 3 weeks for up to six courses.
Patients will be evaluated at least every 3 months for 1 year and every 6 months for up to 2 years.
If you are interested in participating in a clinical trial, contact your doctor for a referral or call a trial contact person listed below. You may see the same contact person listed at more than one site, however, if you call the number listed you can ask to speak to the study coordinator or person involved with the specific trial you are interested in. If you have questions about cancer or clinical trials, call the Cancer Information Service at 1-800-4-CANCER (1-800-422-6237). General information about clinical trials, including risks, benefits, and costs, can be found on
NCI's Web site.
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| U.S.A. |
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| California |
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Castro Valley |
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| | East Bay Radiation Oncology Center |
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| | James Feusner, MD | |
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| | Eden Medical Center |
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| | James Feusner, MD | |
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| | Valley Medical Oncology Consultants - Castro Valley |
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| | James Feusner, MD | |
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Fremont |
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| | Valley Medical Oncology |
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| | James Feusner, MD | |
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Oakland |
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| | Alta Bates Summit Medical Center - Summit Campus |
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| | Clinical Trials Office - Alta Bates Summit Medical Center - Summit Campus | |
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| | Bay Area Breast Surgeons, Incorporated |
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| | James Feusner, MD | |
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| | CCOP - Bay Area Tumor Institute |
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| | James Feusner, MD | |
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| | Highland General Hospital |
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| | James Feusner, MD | |
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| | Larry G Strieff MD Medical Corporation |
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| | James Feusner, MD | |
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| | Tom K Lee, Incorporated |
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| | James Feusner, MD | |
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Pleasanton |
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| | Valley Care Medical Center |
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| | James Feusner, MD | |
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| | Valley Medical Oncology Consultants - Pleasanton |
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| | James Feusner, MD | |
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San Diego |
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| | Kaiser Permanente Medical Office -Vandever Medical Office |
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| | Han Koh | |
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San Pablo |
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| | Doctors Medical Center - San Pablo Campus |
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| | James Feusner, MD | |
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| Connecticut |
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Middletown |
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| | Middlesex Hospital Cancer Center |
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| | Mark Kimmel, MD | |
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| Delaware |
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Lewes |
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| | Tunnell Cancer Center at Beebe Medical Center |
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| | Clinical Trials Office - Tunnell Cancer Center | |
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Newark |
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| | CCOP - Christiana Care Health Services |
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| | Clinical Trial Office - CCOP - Christiana Care Health Services | |
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| Florida |
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Fort Lauderdale |
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| | Michael and Dianne Bienes Comprehensive Cancer Center
at Holy Cross Hospital |
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| | Clinical Trials Office - Michael and Dianne Bienes Comprehensive Cancer Center | |
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Jupiter |
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| | Ella Milbank Foshay Cancer Center at Jupiter Medical Center |
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| | Clinical Trials Office - Ella Milbank Foshay Cancer Center | |
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| Georgia |
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Savannah |
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| | Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center |
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| | Clinical Trials Office - Curtis and Elizabeth Anderson Cancer Institute | |
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| Illinois |
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La Grange |
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| | La Grange Memorial Hospital |
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| | Clinical Trials Office - La Grange Memorial Hospital | |
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| Indiana |
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Elkhart |
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| | Elkhart General Hospital |
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| | Rafat Ansari, MD, FACP | |
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Kokomo |
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| | Howard Community Hospital |
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| | Rafat Ansari, MD, FACP | |
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La Porte |
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| | Center for Cancer Therapy at LaPorte Hospital and Health Services |
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| | Rafat Ansari, MD, FACP | |
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South Bend |
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| | CCOP - Northern Indiana CR Consortium |
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| | Rafat Ansari, MD, FACP | |
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| | Memorial Hospital of South Bend |
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| | Clinical Trials Office - Memorial Hospital of South Bend | |
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| | Saint Joseph Regional Medical Center |
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| | Rafat Ansari, MD, FACP | |
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| Iowa |
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Iowa City |
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| | Holden Comprehensive Cancer Center at University of Iowa |
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| | Cancer Information Service | |
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| Maryland |
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Baltimore |
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| | Greenebaum Cancer Center at University of Maryland Medical Center |
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| | Clinical Trials Office - Greenebaum Cancer Center at University of Maryladn Medical Center | |
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Elkton MD |
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| | Union Hospital Cancer Program at Union Hospital |
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| | Stephen Grubbs, MD | |
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| Massachusetts |
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Boston |
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| | Dana-Farber/Brigham and Women's Cancer Center |
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| | Clinical Trials Office | |
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| | Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute |
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| | Clinical Trials Office - Dana-Farber/Harvard Cancer Center | |
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| | Massachusetts General Hospital |
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| | Clinical Trials Office - Massachusetts General Hospital | |
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Lowell |
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| | Lowell General Hospital |
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| | Pasi Janne, MD, PhD | |
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Peabody |
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| | NSMC Cancer Center - Peabody |
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| | Pasi Janne, MD, PhD | |
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South Weymouth |
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| | South Shore Hospital |
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| | Pasi Janne, MD, PhD | |
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| Michigan |
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St. Joseph |
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| | Lakeland Regional Cancer Care Center - St. Joseph |
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| | Rafat Ansari, MD, FACP | |
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| Missouri |
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Columbia |
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| | Ellis Fischel Cancer Center at University of Missouri - Columbia |
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| | Clinical Trial Office - Ellis Fischel Cancer Center | |
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| | Veterans Affairs Medical Center - Columbia (Truman Memorial) |
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| | Michael Perry, MD | |
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Saint Louis |
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| | Arch Medical Services, Incorporated at Center for Cancer Care and Research |
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| | Alan Lyss, MD | |
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| | Missouri Baptist Cancer Center |
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| | Alan Lyss, MD | | Ph: | 314-996-5569 | | 800-392-0936 |
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| | Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis |
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| | Ramaswamy Govindan, MD | |
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| Nebraska |
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Grand Island |
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| | Saint Francis Cancer Treatment Center at Saint Francis Memorial Health Center |
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| | Margaret Kessinger, MD | | Ph: | 308-398-5450 | | 800-998-2119 |
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North Platte |
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| | Callahan Cancer Center at Great Plains Regional Medical Center |
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| | Clinical Trials Office - Callahan Cancer Center at Great Plains Regional Medical Center | |
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Omaha |
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| | UNMC Eppley Cancer Center at the University of Nebraska Medical Center |
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| | Clinical Trials Office - UNMC Eppley Cancer Center at the University of Nebraska Medical Center | |
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| Nevada |
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Las Vegas |
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| | CCOP - Nevada Cancer Research Foundation |
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| | John Ellerton, MD, CM | |
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| | University Medical Center of Southern Nevada |
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| | John Ellerton, MD, CM | |
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| New Hampshire |
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Nashua |
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| | Oncology Center at St. Joseph Hospital |
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| | Douglas Tisdale | |
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| New Jersey |
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Voorhees |
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| | Cancer Institute of New Jersey at Cooper - Voorhees |
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| | Clinical Trials Office - Cancer Institute of New Jersey at Cooper University Hospital - Voorhees | |
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| New York |
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Buffalo |
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| | Roswell Park Cancer Institute |
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| | Clinical Trials Office - Roswell Park Cancer Institute | |
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East Syracuse |
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| | CCOP - Hematology-Oncology Associates of Central New York |
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| | Jeffrey Kirshner, MD | |
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New York |
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| | Memorial Sloan-Kettering Cancer Center |
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| | Vincent Miller, MD | | Ph: | 212-639-2000 | | 800-525-2225 |
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| | Ralph Lauren Center for Cancer Care and Prevention |
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| | Vincent Miller, MD | |
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Syracuse |
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| | SUNY Upstate Medical University Hospital |
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| | Clinical Trials Office - SUNY Upstate Medical University Hospital | |
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| North Carolina |
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Chapel Hill |
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| | Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill |
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| | Clinical Trials Office - Lineberger Comprehensive Cancer Center | | Ph: | 877-668-0683; 919-966-4432 | | |
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Charlotte |
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| | Presbyterian Cancer Center at Presbyterian Hospital |
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| | Clinical Trials Office - Presbyterian Cancer Center at Presbyterian Hospital | |
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Durham |
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| | Duke Comprehensive Cancer Center |
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| | Clinical Trials Office - Duke Comprehensive Cancer Center | |
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Goldsboro |
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| | Wayne Memorial Hospital, Incorporated |
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| | James Atkins, MD | |
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Hendersonville |
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| | Pardee Memorial Hospital |
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| | James Radford, MD | |
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Kinston |
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| | Kinston Medical Specialists |
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| | Peter Watson, MD | | Ph: | 252-559-2200 ext. 201 | | |
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| Ohio |
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Columbus |
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| | Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center |
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| | Clinical Trials Office - OSU Comprehensive Cancer Center | |
| | Email:
osu@emergingmed.com |
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| Oklahoma |
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Oklahoma City |
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| | Cancer Care Associates - Mercy Campus |
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| | Howard Ozer, MD, PhD | |
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| | Oklahoma University Cancer Institute |
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| | Howard Ozer, MD, PhD | |
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| Rhode Island |
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Pawtucket |
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| | Memorial Hospital of Rhode Island |
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| | Humera Khurshid | |
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Providence |
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| | Miriam Hospital |
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| | Clinical Trials Office - Miriam Hospital | |
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| | Rhode Island Hospital Comprehensive Cancer Center |
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| | Clinical Trials Office - Rhode Island Hospital Comprehensive Cancer Center | |
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| South Carolina |
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Charleston |
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| | Roper St. Francis Cancer Center at Roper Hospital |
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| | James Orcutt, MD | |
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Florence |
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| | McLeod Regional Medical Center |
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| | Clinical Trials Office - McLeod Regional Medical Center | |
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Greenville |
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| | CCOP - Greenville |
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| | Jeffrey Giguere, MD, FACP | |
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| Vermont |
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Berlin |
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| | Mountainview Medical |
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| | George Sanders | |
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Burlington |
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| | Fletcher Allen Health Care - University Health Center Campus |
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| | Clinical Trials Office - Fletcher Allen Health Care | |
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| Virginia |
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Richmond |
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| | Virginia Commonwealth University Massey Cancer Center |
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| | Clinical Trials Office -Virginia Commonwealth University Massey Cancer Center | |
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