Malaria deaths in Gambia drop steeply-study

Reuters | October 30, 2008

Providing pregnant women and children with insecticide-treated bed nets has sharply cut malaria deaths in the West African nation of Gambia, according to a study published on Friday.

The findings suggest health officials in other parts of Africa could eliminate the disease as a public health problem in a region where malaria kills a child every 30 seconds, David Conway and colleagues at the Medical Research Council UK reported in the journal Lancet.

"We have seen that it has gone down and stayed down," Conway said. "There is no evidence of an upsurge but we are aware that with an infectious disease you can never know for sure."

The World Health Organization estimates malaria killed 881,000 people and infected 247 million people worldwide in 2006, the latest year for which figures were available. Some malaria experts say those numbers underestimate the problem.

The disease -- caused by a parasite transmitted by mosquitoes -- has become resistant to some drugs and work on a vaccine has been slow. One effective treatment is Novartis AG's Coartem.

A separate study published in the Public Library of Science journal PLoS Pathogens said Dutch researchers have worked out the characteristics of a large number of parasite proteins that may prove useful in developing a vaccine.
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Malaria takes on the top meds

Like a basketball team that plays best against its toughest opponents, the parasite that causes malaria is showing signs of thwarting the most potent drugs currently used against it. Scientists report that top-line drugs called artemisinins take nearly twice as long to knock out the parasite in people who contract malaria in western Cambodia as the drugs take in other areas — suggesting the parasite is finding ways to thwart the drugs' effects.

EU Pesticide Regulations & Malaria Control

The European Union is currently considering a new regulatory regime for pesticides used in agriculture. The rationale for the new regulations, which will come into force in Fall/Autumn 2008, is to reduce pesticide residues on produce and to limit exposure to chemicals that may cause cancer or act as endocrine disruptors.

March of Washingtons

Visit the March of Washingtons website at www.marchofwashingtons.org - find out how you can help in the fight against malaria, see pictures from other marches, learn more about treatment for malaria and the prevalence of substandard antimalarial drugs, check out the supporters and Founding Partners, tell us about your March of Washingtons and upload your picture.

Articles

Pesticides: an alternative view from Africa Fighting Malaria

The amendments to EU Directive 91/414 are the subject of enormous debate and gnashing of teeth. Malaria scientists and public health experts are exercised about these regulations because of the implications for disease control and have submitted a letter of petition to the EU.

Killing With Kindness

The UN convened this week in New York to discuss its Millennium Development Goals and the aim of "ending poverty by 2015." Delegates and a rock star boasted of billions of dollars transferred to African governments, while failed schemes prompted activists to call for even more money. Donors re-branded the failed Roll Back Malaria scheme and promised US$3 billion.

AFM Bulletin #2: What makes a malaria control program sustainable and successful?

Malaria is an extremely devastating and complex disease, and controlling it is neither simple nor easy. Successful and sustainable malaria control programs have an integrated and balanced approach that covers all of the technical, research, and scientific components of malaria control. These programs also have firm political commitments by national governments that ensure sustainable funding and support for malaria control, and policies that are guided by scientific evidence. A good example of a successful and sustainable program is the Lubombo Spatial Development Initiative (LSDI).

No money in malaria

In the last week of July the malaria community from the East and Southern Africa regions came together in Lusaka, Zambia for their annual planning and review meeting. This important meeting provides a forum to review the malaria control programmes of each of the 22 countries in the region and this year's specific theme was "Improving Malaria Diagnosis".

Private Partnerships: Key to Malaria Control

For many years, the politics of malaria control have been such that IRS and the use of DDT have been discouraged either officially by WHO or de facto by donor agencies that have failed to provide funding for IRS programs.

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News

US provides anti-malaria community grants to seven African countries

The U.S., through the U.S. Agency for International Development (USAID), on Thursday announced over US$11 million grants to eight organizations working in seven African countries to extend the coverage of their malaria prevention and control activities.

Malaria advances still not reaching patients, warns charity

A new report from the international medical organisation Médecins Sans Frontières (MSF) says that measures to ensure new diagnostics and artemisinin-based combination therapy (ACT) actually reach patients are now crucial. Merely shipping drug treatment to resource-poor countries is not enough, say the authors, citing weak distribution and health systems and a lack of qualified staff as just some of the problems.

Mozambique: Christian Charity Promises Support Against Malaria

The president and chief executive officer of the US-based Christian charity, World Vision International, Dean Hirsch, has promised that his organisation will step up its support for the fight against malaria in Mozambique, to reduce the high mortality from the disease.

Sweet pill tackles child malaria

A cherry-flavoured pill which is easy to swallow could help save the lives of children in malaria-affected areas, say researchers in Tanzania.

EU pesticides reform could hinder malaria fight in Africa

Proposed EU pesticides approvals reform could hinder the fight against malaria in Africa, according to a leading malaria campaign group. The proposals ignore the risks of not using insecticides to protect crops and human health. In most developing countries, agricultural pests and disease-spreading insects pose a far greater and more immediate threat to human health than insecticides, the Africa Fighting Malaria group says.

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Research & Policies

Trends in malaria morbidity following the introduction of artesunate plus amodiaquine combination in M'lomp village dispensary, south-western Senegal

In Thailand, South Africa and Zanzibar, a decrease in malaria morbidity was observed following the introduction of artemisinin-based combination therapy (ACT). In Senegal, therapeutic trials supervised the in vivo efficacy of artesunate plus amodiaquine from 1999 to 2005 at the M'lomp village dispensary. The trends in malaria morbidity in this village were evaluated from 2000 to 2002.

A Nationwide Survey of the Quality of Antimalarials in Retail Outlets in Tanzania

Retail pharmaceutical products are commonly used to treat fever and malaria in sub-Saharan African countries. Small scale studies have suggested that poor quality antimalarials are widespread throughout the region, but nationwide data are not available that could lead to generalizable conclusions about the extent to which poor quality drugs are available in African communities. This study aimed to assess the quality of antimalarials available from retail outlets across mainland Tanzania.

World Malaria Report 2008

Half of the world's population is at risk of malaria, and an estimated 247 million cases led to nearly 881 000 deaths in 2006. The World malaria report 2008 describes the global distribution of cases and deaths, how WHO-recommended control strategies have been adopted and implemented in endemic countries, sources of funding for malaria control, and recent evidence that prevention and treatment can alleviate the burden of disease.

Quantity and Quality: An Rx for Efficient Drug Purchasing

Drug procurement agencies and organizations spend billions of dollars on drugs for patients in the developing world. These drugs are essential to the health of many millions of patients--but only if they are safe and effective. The World Health Organization (WHO) and the Global Fund to Fight AIDS, Tuberculosis and Malaria offer "prequalification" programs designed to help drug procurers identify suppliers of safe and effective drugs.

Obstacles to prompt and effective malaria treatment lead to low community-coverage in two rural districts of Tanzania

Malaria is still a leading child killer in sub-Saharan Africa. Yet, access to prompt and effective malaria treatment, a mainstay of any malaria control strategy, is sub-optimal in many settings. Little is known about obstacles to treatment and community-effectiveness of case-management strategies. This research quantified treatment seeking behaviour and access to treatment in a highly endemic rural Tanzanian community. The aim was to provide a better understanding of obstacles to treatment access in order to develop practical and cost-effective interventions.

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