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Osteosarcoma/Malignant Fibrous Histiocytoma of Bone Treatment (PDQ®)
Patient Version   Health Professional Version   En español   Last Modified: 05/23/2008



Description






Stage Explanation






Treatment Option Overview






Localized Osteosarcoma and Malignant Fibrous Histiocytoma of Bone






Metastatic Disease at Diagnosis






Recurrent Osteosarcoma






To Learn More About Osteosarcoma and Malignant Fibrous Histiocytoma of Bone






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Changes to This Summary (05/23/2008)






About PDQ



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Stage Explanation

Stages of osteosarcoma
Localized osteosarcoma
Metastatic osteosarcoma
Recurrent



Stages of osteosarcoma

Once osteosarcoma has been found, more tests may be done to find out if cancer cells have spread to other parts of the body. This is called staging. At present, there is no staging system for osteosarcoma. Instead, most patients are grouped depending on whether cancer is found in only one part of the body (localized disease) or whether the cancer has spread from one part of the body to another (metastatic disease). Your doctor needs to know where the cancer is located and how far the disease has spread to plan treatment. The following groups are used for osteosarcoma:

Localized osteosarcoma

The cancer cells have not spread beyond the bone or nearby tissue in which the cancer began.

Metastatic osteosarcoma

The cancer cells have spread from the bone in which the cancer began to other parts of the body. The cancer most often spreads to the lungs. It may also spread to other bones. About one in five patients with osteosarcoma has cancer that has metastasized by the time it is diagnosed.

In multifocal osteosarcoma, tumors appear in 2 or more bones, but have not spread to the lungs.

Recurrent

Recurrent disease means that the cancer has come back (recurred) after it has been treated. It may come back in the tissues where it first started or it may come back in another part of the body. Osteosarcoma most often recurs in the lung. When osteosarcoma recurs, it is usually within 2 to 3 years after treatment is completed. Later recurrence is possible, but rare.

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