Oral complications of cancer, including oral mucositis,[1] are among the most devastating of both short- and long-term problems encountered by people with cancer because they affect eating and communication, the most basic of human activities. Patients with these problems can become withdrawn, socially avoidant, and even clinically depressed as a result of the difficulties and frustrations they encounter living with oral complications. When employing psychotropic drug interventions in treatment of such patients, it is important to choose them with an eye toward improving or at least not worsening their oral complications. For example, in the treatment of depression in such patients, highly anticholinergic drugs should be avoided in patients with xerostomia and salivary problems. (Refer to the PDQ summaries on Anxiety Disorder and Depression for more information.)

Supportive care including education and symptom management are important for patients experiencing oral complications related to cancer therapy. It is important to closely monitor each patient’s level of distress, ability to cope, and response to treatment. This approach provides a setting for the health professional to demonstrate concern for the patient’s complications and to educate the patient and family caregivers. Comprehensive supportive care from staff and family can enhance the patient’s ability to cope with cancer and its complications.

References

1. Dodd MJ, Dibble S, Miaskowski C, et al.: A comparison of the affective state and quality of life of chemotherapy patients who do and do not develop chemotherapy-induced oral mucositis. J Pain Symptom Manage 21 (6): 498-505, 2001.  [PUBMED Abstract]
   
   

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