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Brief Summary

GUIDELINE TITLE

Pediatric eye evaluations: I. Screening. II. Comprehensive ophthalmic evaluation.

BIBLIOGRAPHIC SOURCE(S)

  • American Academy of Ophthalmology Pediatric Ophthalmology/Strabismus Panel. Pediatric eye evaluations: I. Screening; II. Comprehensive ophthalmic evaluation. San Francisco (CA): American Academy of Ophthalmology; 2007. 32 p. [89 references]

GUIDELINE STATUS

This is the current release of the guideline.

It updates a previous version: American Academy of Ophthalmology Pediatric Ophthalmology Panel. Pediatric eye evaluations. San Francisco (CA): American Academy of Ophthalmology; 2002 Oct. 22 p. [36 references]

All Preferred Practice Patterns are reviewed by their parent panel annually or earlier if developments warrant and updated accordingly. To ensure that all Preferred Practice Patterns are current, each is valid for 5 years from the "approved by" date unless superseded by a revision.

BRIEF SUMMARY CONTENT

 
RECOMMENDATIONS
 EVIDENCE SUPPORTING THE RECOMMENDATIONS
 IDENTIFYING INFORMATION AND AVAILABILITY
 DISCLAIMER

 Go to the Complete Summary

RECOMMENDATIONS

MAJOR RECOMMENDATIONS

Ratings of importance to the care process (A-C) and ratings of strength of evidence (I-III) are defined at the end of the "Major Recommendations" field.

Screening

Age-appropriate eye and vision evaluations should be performed in the newborn period and at all subsequent health supervision visits, [A:III] because different childhood eye problems may be detected at each visit and new problems can arise during childhood.

At a child's first examination by a new primary care provider, a history of risk factors for eye and vision abnormalities should be elicited. [A:III] At each scheduled well-child examination, the primary care provider should ask the parent/caregiver about the baby's visual interactions and possible eye or vision problems. [A:III]

The screening examination should include examination of the red reflex to detect abnormalities of the ocular media; external inspection to detect ocular abnormalities; pupil examination; visual acuity on an age-appropriate basis; and, after 6 months of age, the corneal light reflection test (Hirschberg reflex) and cover testing for ocular alignment as well as motility testing. [A:III]

Children who fail a screening should be referred for a comprehensive pediatric ophthalmic evaluation after the first screening failure. [A:III]

If a child is unable to cooperate for vision testing at 3 years of age, a second attempt should be made within 6 months. [A:III] If the child is 4 years old, a second attempt should be made within the month (American Academy of Pediatrics, 2003). [A:III] Although the child may be re-screened if screening is inconclusive or unsatisfactory, undue delays should be avoided; if retesting is inconclusive, referral for a comprehensive ophthalmic evaluation is indicated (Maguire & Vision in Preschoolers Study Group, 2007). [A:III]

Referral Plan

If eye and vision abnormalities or their risk factors are suspected or identified at a screening examination, an appropriate referral plan should be initiated and recorded. [A:III] The tables below list specific examples of indications for a referral for a comprehensive pediatric ophthalmic evaluation.

Comprehensive Ophthalmic Evaluation

History

Although a thorough history generally includes the following items, the exact composition varies with the patient's particular problems and needs:

  • Demographic data, including identification of parent/caregiver, and patient's gender and date of birth [A:III]
  • Documentation of identity and relationship of historian [B:III]
  • The identity of other pertinent health care providers [A:III]
  • The chief complaint and reason for the eye evaluation [A:III]
  • Current eye problems [A:III]
  • Ocular history, including other eye problems, diseases, diagnoses, and treatments [A:III]
  • Systemic history; birth weight; prenatal and perinatal history that may be pertinent (e.g., alcohol, drug, and tobacco use during pregnancy); past hospitalizations and operations; general health and development [A:III]
  • Current medications and allergies. [A:III]
  • Family history of eye conditions and relevant systemic diseases. [A:III] A social history, including racial or ethnic heritage, is germane for certain diagnostic considerations such as sickle cell anemia or Tay-Sachs disease.
  • Review of systems. [B:III]

Examination

Documentation of the child's level of cooperation with the examination can be useful in interpreting the results and in making comparisons among the examinations over time. In general, the examination may include the following elements:

  • Assessment of visual acuity and fixation pattern [A:III]
  • Ocular alignment and motility [A:III]
  • Red reflex or binocular red reflex (Brückner) test [A:III]
  • Pupil examination [A:III]
  • External examination [A:III]
  • Anterior segment examination [A:III]
  • Cycloplegic retinoscopy/refraction [A:III]
  • Funduscopic examination [A:III]

Other tests that may be indicated in selected patients:

  • Binocularity/stereoacuity testing
  • Sensorimotor evaluation (e.g., strabismus, suspected neurological disease)

Diagnosis and Management

Category I: Low Risk

When the evaluation is normal, the ophthalmologist reassures the patient and the parent/caregiver and advises as to the appropriate interval for re-examination. Although this group of patients is considered low risk, periodic eye screening by the primary care provider should be continued. [A:III] Patients should undergo a comprehensive pediatric ophthalmic evaluation if new ocular symptoms, signs, or risk factors for ocular disease develop. [A:III]

Category II: High Risk

When the evaluation reveals risk factors for developing ocular disease or signs that are suggestive of an abnormal condition, the patient is considered to be at high risk. The ophthalmologist should determine an appropriate follow-up interval for each patient based on the findings. [A:III]

Category III: Requiring Intervention

Most patients with abnormal signs and symptoms can be diagnosed and treated solely on the basis of a comprehensive pediatric eye evaluation. Recommendations for appropriate treatment and follow-up will vary with the patient. The Amblyopia Preferred Practice Patterns (PPP) and Esotropia and Exotropia PPP contain specific recommendations for management of these conditions (see the National Guideline Clearinghouse [NGC] summaries of the American Academy of Ophthalmology PPPs Amblyopia and Esotropia and exotropia.

Optical correction should be considered if the visual acuity can be improved, if ocular alignment can be improved, to prevent or treat amblyopia, to treat strabismus, or if the patient has asthenopia. [A:III] The goals when prescribing eyeglasses for young children are to achieve good vision, straight eyes, normal binocular vision, and acceptance of the eyeglasses.

Table: Indications for Referral for a Comprehensive Pediatric Ophthalmic Evaluation

Indication Specific Examples
Risk factors (general health problems, systemic disease, or use of medications that are known to be associated with eye disease and visual abnormalities)
  • Prematurity (birth weight less than 1500 grams or gestational age 30 weeks or less)
  • Retinopathy of prematurity
  • Intrauterine growth retardation
  • Perinatal complications (evaluation at birth and at 6 months)
  • Neurological disorders or neurodevelopmental delay (upon diagnosis)
  • Juvenile rheumatoid arthritis (upon diagnosis)
  • Thyroid disease
  • Cleft palate or other craniofacial abnormalities
  • Diabetes mellitus (5 years after onset)
  • Systemic syndromes with known ocular manifestations (at 6 months or upon diagnosis)
  • Chronic systemic steroid therapy or other medications known to cause eye disease
  • Suspected child abuse
A family history of conditions that cause or are associated with eye or vision problems
  • Retinoblastoma
  • Childhood cataract
  • Childhood glaucoma
  • Retinal dystrophy/degeneration
  • Strabismus
  • Amblyopia
  • Eyeglasses in early childhood
  • Sickle cell disease
  • Systemic syndromes with ocular manifestations
  • Any history of childhood blindness not due to trauma in a parent or sibling
Signs or symptoms of eye problems by history or observations by family members*
  • Defective ocular fixation or visual interactions
  • Abnormal light reflex (including both the corneal light reflections and the red fundus reflection)
  • Abnormal or irregular pupils
  • Large and/or cloudy eyes
  • Drooping eyelid
  • Lumps or swelling around the eyes
  • Ocular alignment or movement abnormality
  • Nystagmus (shaking of eyes)
  • Persistent tearing, ocular discharge
  • Persistent or recurrent redness
  • Persistent light sensitivity
  • Squinting/eye closure
  • Persistent head tilt
  • Learning disabilities or dyslexia

Note: These recommendations are based on panel consensus.

*"Headache" is not included since it is rarely caused by eye problems in children. This complaint should first be evaluated by the primary care physician.

Table. Recommended Ages and Methods for Pediatric Eye Evaluation Screening

Recommended Age Method Indications for Referral to an
Ophthalmologist
Newborn to 3 months Red reflex Absent, white, dull, opacity, or asymptomatic
External inspection Structural abnormality
Pupil examination Irregular shape, unequal size, poor or unequal reaction
3 to 6 months (approximately) Fix and follow Failure to fix and follow in a cooperative infant
Red reflex Absent, white, dull, opacity, or asymptomatic
External inspection Structural abnormality
Pupil examination Irregular shape, unequal size, poor or unequal reaction
6 to 12 months and until child is able to cooperate for verbal visual acuity Fix and follow with each eye Failure to fix and follow
Alternate occlusion Failure to object equally to covering each eye
Corneal light reflex Asymmetric or displaced
Red reflex Absent, white, dull, opacity, or asymptomatic
External inspection Structural abnormality
Pupil examination Irregular shape, unequal size, poor or unequal reaction
3 years and 4 years (approximately) Visual acuity* (monocular) 20/50 or worse, or 2 lines of difference between the eyes
Corneal light reflection/cover-uncover Asymmetric/ocular refixation movements
Red reflex Absent, white, dull, opacity, or asymptomatic
External inspection Structural abnormality
Pupil examination Irregular shape, unequal size, poor or unequal reaction
5 years (approximately) Visual acuity* (monocular) 20/40 or worse, or 2 lines of difference between the eyes
All other tests and referral indications are as in age 3 and 4 years.  
Every 1 to 2 years after age 5 Visual acuity* (monocular) 20/30 or worse, or 2 lines of difference between the eyes
All other tests and referral indications are as in age 3 and 4 years  

Note: These recommendations are based on panel consensus. Although the child may be retested if screening is inconclusive or unsatisfactory, undue delays should be avoided; if inconclusive on retesting, referral for a comprehensive pediatric ophthalmic evaluation is indicated. [A:III]

*Figures, letters, "tumbling E" or optotypes, LEA symbols (Precision Vision, Inc., La Salle, IL), vision testing machines.

Table: Consensus Guidelines for Prescribing Eyeglasses for Young Children [A:III]

Condition Diopters
Age 0-1 year Age 1-2 years Age 2-3 years
Isometropia (similar refractive error in both eyes)

Myopia

>–5.00 >–4.00 >–3.00

Hyperopia (no manifest deviation)*

>+6.00 >+5.00 >+4.50

Hyperopia with esotropia**

>+3.00 >+2.00 >+1.50

Astigmatism

>3.00 >2.50 >2.00
Anisometropia

Myopia

>–2.50 >–2.50 >–2.00

Hyperopia

>+2.50 >+2.00 >+1.50

Astigmatism

>2.50 >2.00 >2.00
Additional Factors
  • History of previous amblyopia or strabismus surgery
  • Visual acuity
  • Acceptance of eyeglass wear
  • Possible accommodative esotropia/monofixation syndrome
  • Medical comorbidities
  • Developmental delay

Note: These values were generated by consensus and are based solely on professional experience and clinical impressions, because there are no scientifically rigorous published data for guidance. The exact values are unknown and may differ among age groups; they are presented as general guidelines that must be tailored to the individual patient.

*May reduce the correction by up to 50% (but no more than 3.00 diopters) depending on the clinical situation.

**In higher hyperopes, reduction of the cycloplegic refraction may be necessary to achieve eyeglass acceptance.

Definitions:

Ratings of Importance to the Care Process

Level A, defined as most important

Level B, defined as moderately important

Level C, defined as relevant but not critical

Ratings of Strength of Evidence

Level I: Includes evidence obtained from at least one properly conducted, well-designed randomized controlled trial. It could include meta-analyses of randomized controlled trials.

Level II: Includes evidence obtained from the following:

  • Well-designed controlled trials without randomization
  • Well-designed cohort or case-control analytic studies, preferably from more than one center
  • Multiple-time series with or without the intervention

Level III: Includes evidence obtained from one of the following:

  • Descriptive studies
  • Case reports
  • Reports of expert committees/organization (e.g., Preferred Practice Patterns [PPP] Panel consensus with external peer review)

CLINICAL ALGORITHM(S)

None provided

EVIDENCE SUPPORTING THE RECOMMENDATIONS

REFERENCES SUPPORTING THE RECOMMENDATIONS

TYPE OF EVIDENCE SUPPORTING THE RECOMMENDATIONS

The type of supporting evidence is identified and graded for selected recommendations (see "Major Recommendations").

IDENTIFYING INFORMATION AND AVAILABILITY

BIBLIOGRAPHIC SOURCE(S)

  • American Academy of Ophthalmology Pediatric Ophthalmology/Strabismus Panel. Pediatric eye evaluations: I. Screening; II. Comprehensive ophthalmic evaluation. San Francisco (CA): American Academy of Ophthalmology; 2007. 32 p. [89 references]

ADAPTATION

Not applicable: The guideline was not adapted from another source.

DATE RELEASED

1992 Jun (revised 2007 Sep)

GUIDELINE DEVELOPER(S)

American Academy of Ophthalmology - Medical Specialty Society

SOURCE(S) OF FUNDING

American Academy of Ophthalmology without commercial support

GUIDELINE COMMITTEE

Pediatric Ophthalmology/Strabismus Panel, Preferred Practice Patterns Committee

COMPOSITION OF GROUP THAT AUTHORED THE GUIDELINE

Members of the Pediatric Ophthalmology/Strabismus Panel: Linda M. Christmann, MD, Chair; Patrick J. Droste, MD; Sheryl M. Handler, MD, American Association for Pediatric Ophthalmology and Strabismus Representative; Richard A. Saunders, MD; R. Grey Weaver, Jr., MD; Susannah G. Rowe, MD, MPH, Methodologist; Norman Harbaugh, MD, FAAP, American Academy of Pediatrics Representative; Donya A. Powers, MD, American Academy of Family Physicians Representative

Members of the Preferred Practice Patterns Committee: Sid Mandelbaum, MD, Chair; Emily Y. Chew, MD; Linda M. Christmann, MD; Douglas E. Gaasterland, MD; Samuel Masket, MD; Stephen D. McLeod, MD; Christopher J. Rapuano, MD; Donald S. Fong, MD, MPH, Methodologist

FINANCIAL DISCLOSURES/CONFLICTS OF INTEREST

This author has disclosed the following financial relationships from January 2006 to August 2007:

Norman Harbaugh, MD, FAAP: Kids First – Grant support. Kids Time – Equity owner. Medimmune –Lecture fees. Centers for Disease Control, Merck, United Healthcare – Consultant/Advisor

GUIDELINE STATUS

This is the current release of the guideline.

It updates a previous version: American Academy of Ophthalmology Pediatric Ophthalmology Panel. Pediatric eye evaluations. San Francisco (CA): American Academy of Ophthalmology; 2002 Oct. 22 p. [36 references]

All Preferred Practice Patterns are reviewed by their parent panel annually or earlier if developments warrant and updated accordingly. To ensure that all Preferred Practice Patterns are current, each is valid for 5 years from the "approved by" date unless superseded by a revision.

GUIDELINE AVAILABILITY

Electronic copies: Available from the American Academy of Ophthalmology (AAO) Web site.

Print copies: Available from American Academy of Ophthalmology, P.O. Box 7424, San Francisco, CA 94120-7424; telephone, (415) 561-8540.

AVAILABILITY OF COMPANION DOCUMENTS

None available

PATIENT RESOURCES

None available

NGC STATUS

This summary was completed by ECRI on June 30, 1998. The information was verified by the guideline developer on December 1, 1998. This summary was updated on March 12, 2003. The updated information was verified by the guideline developer on April 2, 2003. This NGC summary was updated by ECRI Institute on February 6, 2008. The updated information was verified by the guideline developer on February 27, 2008.

COPYRIGHT STATEMENT

This NGC summary is based on the original guideline, which is subject to the guideline developer's copyright restrictions. Information about the content, ordering, and copyright permissions can be obtained by calling the American Academy of Ophthalmology at (415) 561-8500.

DISCLAIMER

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