From Denver
The most direct route is to travel west on Interstate 70 to Rifle, Colorado. Take the exit for Highway 13, and follow 13 north toward Meeker. About 40 miles past Rifle, take a left on Highway 64 west toward Rangely. Follow 64 west to Dinosaur, Colorado (about 78 miles). In Dinosaur, turn west (left) on Highway 40 to Jensen, Utah. Turn north (right) on Utah 149 and follow the signs for the Visitor Center. Driving time from Denver is about 5 1/2 hours.
From Salt Lake City
Take I-80 east out of the city. Follow I-80 for approximately 25 miles, and then take the exit for Highway 40 east toward Vernal. Follow 40 east to Vernal (about 160 miles). Go through Vernal and follow Highway 40 to Jensen, Utah (10 miles east of Vernal). Turn north (left) on Utah 149 and follow the signs for the Visitor Center. Driving time from Salt Lake City is about 4 hours.