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In easy-to-understand language
Note: The terms "immunization," "vaccination," and "inoculation" are used to mean essentially the same thing throughout this site.
HOW DO VACCINES WORK?
Parents are constantly concerned about the health and safety of their children and they take many steps to protect them. These preventive measures range from child-proof door latches to child safety seats. In the same respect, vaccines work to safeguard children from illnesses and death caused by infectious diseases. Vaccines protect children by helping prepare their bodies to fight deadly diseases..

How Do Vaccines Work?

  • There are a series of steps that a person�s body goes through in learning how to fight off a vaccine-preventable disease:

     

      First - A vaccine is given by a shot or liquid by mouth. An alternative needle-free route is the use of inhalation by aerosol and powder. Most vaccines contain a weakened or dead disease germ or part of a disease germ. Other vaccines use inactivated toxins. Some of the bacteria that cause disease do so by producing toxins that invade the bloodstream.

      Next - The body makes antibodies against the weakened or dead germs in the vaccine.

      Then - These antibodies can fight the real disease germs � which can be lurking all around � if they invade the child�s body. The antibodies will know how to destroy them and the child will not become ill. Most vaccines don�t cause the diseases that are usually caused by viruses and bacteria.

      Finally - Protective antibodies stay on guard in the child�s body to safeguard it from the real disease germs.

  •  

  • After exposure to a live, weakened, or dead germ, the antibodies or memory cells fight infectious diseases and usually stay in a person�s immune system for a lifetime. This protects a person from getting sick again. This protection is called immunity.

Why Are Vaccines Important?

  • It is true that newborn babies are immune to many diseases because they have antibodies they got from their mothers. However, this immunity only lasts about a year. Further, most young children do not have maternal immunity from diphtheria, whooping cough, polio, tetanus, hepatitis B, or Haemophilus influenzae type b.
  • Immunizing individual children also helps to protect the health of our community. People who are sick will be less likely to be exposed to disease germs that can be passed around by unvaccinated children. Immunization also slows down or stops disease outbreaks.
  • If a child is not vaccinated and is exposed to a disease germ, the child�s body may not be strong enough to fight the disease. Before vaccines, many children died of diseases vaccines prevent, like whooping cough, measles, and polio. Those same germs exist today, but babies are now protected by vaccines and so we do not see these diseases as often.

CDC, National Immunization Program:  http://www.cdc.gov/nip

Last updated: May 2001


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