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Guidelines on Overweight and Obesity: Electronic Textbook ![]() |
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OsteoarthritisIndividuals who are
overweight or obese increase their risk for the development of osteoarthritis
(16-18, 91, 92).
The association between increased weight and the risk for development of
knee osteoarthritis is stronger in women than in men (92). In a study of
twin middle-aged women, it was estimated that for every kilogram increase of
weight, the risk of developing osteoarthritis increases by 9 to 13 A randomized controlled trial of 6 months' duration examined the effect of weight loss on clinical improvement in patients with osteoarthritis (176). Patients taking phentermine had an average weight loss of 12.6 percent after 6 months while the control group had an average weight loss of 9.2 percent. There was improvement in pain-free range of motion and a decrease in analgesic use in association with weight loss; patients with knee disease showed a stronger association than those with hip disease. Similarly, improvement of joint pain was observed in individuals who had undergone gastric stapling, resulting in an average weight loss of 45 kg (99 lb) (94, 95). |