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United States National Library of Medicine National Institutes of Health

Principles of MEDLINE Subject Indexing

To better understand how to use MeSH when searching MEDLINE, it is helpful to understand the basic principles of subject indexing for MEDLINE.

Subject indexing includes:

  • reviewing a journal article (or other material such as a letter or editorial)
  • determining its subject content, and
  • describing that content using a controlled vocabulary.  

Purpose of indexing with controlled vocabulary:

  • to facilitate search retrieval by eliminating (or accounting for) the use of variant terminology for the same concept.

Types of vocabulary terms:

  • MeSH headings (“descriptors”)
  • Subheadings (“qualifiers”)
  • Check tags 
    • A special class of MeSH headings that must be considered routinely for every article
      • Primarily headings covering species (including Humans), gender, and human age groups
      • Also cover:
        • historical time periods
        • pregnancy
    • Usually are indexed even if merely mentioned, unlike other MeSH headings
    • For review articles, usually are indexed only if the main point of the article
    • Humans is not selected for articles involving institutions that serve humans, e.g., clinics, hospitals
    • Some check tags (Animals, Humans, Male, Female, In Vitro, Comparative Study, and research support terms) can never be designated as the main point of the article
  • Publication Characteristics (or Types): describe the item being indexed rather than its topic.   There are 3 main categories:
    • Publication Components, e.g., English Abstract
    • Publication Formats, e.g., Lectures, Letter
    • Study Characteristics, e.g., Clinical Trial, Twin Study
  • Supplementary Concept Records: allow the indexing/searching of chemicals (in the broadest sense) which are not MeSH headings

Philosophy of indexing

  • The content and format of each item are fully and adequately described
  • The most specific vocabulary terms are used
  • The indexer’s job is only to index, not to interpret, evaluate or diagnose

Last updated: 21 December 2007
First published: 25 January 2006
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