Endocrinology, Nutritional Metabolism, and Reproductive Sciences

[Endocrinology, Metabolism, Nutrition, and Reproductive Sciences (EMNR) Integrated Review Group]

[ F06 Roster ]

F06 reviews fellowship applications involved in areas of endocrinology, metabolism, nutrition, and reproductive sciences. Included are applications for a broad spectrum of research related to all aspects of general endocrinology, gametogenesis and reproductive physiology, pregnancy and lactation, and nutrient metabolism. Examples of specific areas covered are listed below.

• Hormones and endocrine glands associated with the reproductive processes
• Physiological, pathophysiological, and molecular processes involving hypothalamic, pituitary, pineal, thyroid, adrenal, gonadal, and pancreatic hormones
• Gametogenesis, fertilization, embryology and development from the early stages of gonad development and through implantation of the embryo, pregnancy, and parturition, including neonatal development and maternal/fetal physiology
• Evaluation of nutritional status throughout the life cycle
• Nutrient and energy metabolism
• Metabolic and molecular functions in Type II diabetes
• Adipocyte function, including nutrient storage and release, and communication with other organs and tissues
• Mechanisms, pathogenesis, and treatment of obesity and Type II diabetes
• Differentiation, development, growth, and function of pancreatic islets

Shared Interests:

With F02A (Behavioral Neuroscience): Studies in the area of neuroendocrinology focusing on the interactions of hormones with neuronal systems and behavior may be assigned to F02A; applications concerning target organs of hormones or focusing primarily on endcrine systems may be assigned to F06.

With F05 (Cell Biology and Development): Fellowship applications that focus on signal transduction at the cellular and molecular level in context of cell division, cell cycle, cell senescence and death may be assigned to F05. Fellowship applications that address hormone effects in the context of gonadal development through implantation of the embryo, as well as aspects of all stages of pregnancy, parturition, neonatal development and maternal/fetal physiology, may be assigned to F06. Fellowship applications that focus on stem cell transformation and differentiation are of interest to both panels and should be assigned based on the thrust of the application with F05 more concerned with the basic process of cellular differentiation and F06 more concerned with the endocrinology of the stem cell line.

With F07 (Immunology) regarding diabetes: Fellowship applications on autoimmune diabetes may be assigned to F07; fellowship applications on non-immune diabetes may be assigned to F06.

With F09 (Oncological Sciences): Fellowship applications that focus on carcinogenesis, tumor development and treatment, and metastasis could be assigned to F09; fellowship applications that focus on the role of hormones in the development of cancer could be assigned to F06.

With F10 (Physiology and Pathobiology of Organ Systems): Shared interests exist in the areas of exercise physiology, renal pathophysiology, and lipoprotein metabolism.  Exercise physiology in the context of respiratory function and regulation may be assigned to F10; exercise physiology in the context of skeletal muscle functions related to insulin action, insulin resistance and type 2 diabetes may be assigned to F06. Studies that focus on effects of nutrient metabolism in diabetic nephropathy and other diabetes-induced metabolic abnormalities may be assigned to F06; studies that focus on the underlying pathophysiology of the process of renal derangement and of muscle physiology addressing the role of actin and myosin and other factors in muscle contractility may be assigned to F10. In addition, F10 may be assigned applications on renal transport mechanisms intrinsic to diabetic nephropathy, diabetes-induced renal pathology, diabetes-induced urology pathology, and organ or environmental toxicology. Studies that focus on the lipoprotein risk factors or the nutrient/metabolic fate of substances in the context of type 2 diabetes and obesity may be assigned to F06; studies that focus on lipoprotein metabolism in the context of coronary artery diseases, vessel wall biology, and pathogenesis of atherosclerosis may be assigned to F10.