F14: Technology Development

Technology Development

[Bioengineering Sciences and Technologies (BST) Integrated Review Group]

[ F14 Roster ]

The Technology Development panel reviews fellowship applications that focus on fundamental aspects of bioengineering and technology development in their early stages, before specific practical uses are proven.  Fellowship applications need not be hypothesis-driven and may instead focus on the development of specific products, methods, or principles.  Fellowship applications that propose basic engineering science, methodology, and technology development in the areas of gene and drug delivery, biomaterials and biointerfaces, data management and analysis, modeling and analysis of biological systems, instrumentation systems and development, and microscopic imaging are appropriate.  Examples of specific areas covered are listed below:

  • Gene and drug delivery, including viral and nonviral vector development and testing, siRNA; delivery systems such as electroporation, ultrasound, transfection, and liposomes; targeted nanoparticles, and controlled release vehicles; monitoring expression or release of agents delivered
     
  • Biomaterials and biointerfaces, including surface chemistry, materials science, biomimetics, nanoparticles, biocompatibility and tissue interactions, tissue engineering

  • Data management and archiving, bioinformatics algorithms, design and integration of large datasets, grid computing, ontologies, data mining and data representation and visualization

  • Mathematical modeling and computational biology, including algorithm development and statistics for simulating the function and behavior of molecules, networks and pathways, organs and tissues

  • Instrumentation and systems for the analysis, detection, separation, synthesis, and screening of biological and medicinal molecules and cells, including high throughput technology, device fabrication, micro/nanofluidics, lithography, LIMS systems, robotics, microarrays and lab-on-a-chip; single-molecule and single-cell studies; HTP assays for proteomics, cell/tissue arrays, and drug screening; remote and computer control systems, wearable monitors, and implantable devices; technology for environmental monitoring such as detectors and sensors for biohazards, pollutants, food contaminants, and pathogens

  • Microscopic imaging technology, including instrumentation (EM, AFM, fluorescent and confocal microscopes), genetic reporters, and probes (FRET pairs, contrast agents, and quantum dots) for visualizing intracellular components and single molecules; image analysis and management, including image enhancement, pattern recognition, reconstruction and tomography, and databases for cellular images

  

Shared Interests:
 

F04A (Chemical and Bioanalytical Science): Fellowship applications that are concerned primarily with elucidating the chemical principles of biologically and medicinally important molecules may be assigned to F04A; fellowship applications that are concerned primarily with the development of new methods, instrumentation, or technology for use in studies of biologically and medicinally important molecules may be assigned to F14.

F04B (Biophysical and Biochemical Science): Fellowship applications that are concerned primarily with elucidating the structural principles, biophysical behavior, and dynamics of biological macromolecules may be assigned to F04B; fellowship applications that are concerned with the development of new methods, instrumentation, or technology for use in studies of biological macromolecules may be assigned to F14.

 

F05 (Cell Biology and Development): Fellowship applications that are concerned primarily with elucidating the basic principles of cell structure, function, regulation, and differentiation may be assigned to F05; fellowship applications that are concerned primarily with the development of new methods, instrumentation, or technology for studies of cell structure, function, regulation, and differentiation may be assigned to F14.

 

With F08 (Genomics, Genetics, DNA Replication, and Gene Expression): Fellowship applications that are concerned primarily with elucidating genetic principles, genome organization, or molecular mechanisms may be assigned to F08; fellowship applications that are concerned primarily with the development of new methods, instrumentation, or technology for studies of genetic principles, genome organization, or molecular mechanisms may be assigned to F14.

 

F13 (Infectious Diseases and Microbiology): Fellowship applications that are concerned primarily with virology and viral pathogenesis, bacteriology and bacterial pathogenesis, fungal pathogenesis, parasitology and parasitic diseases, innate and adaptive host responses to these microbes and viruses, and the development of anti-infective agents to treat and prevent infectious disease may be assigned to F13.  Fellowship applications that are concerned primarily with development of technology for detecting pathogens, high throughput screening technology for identifying inhibitors of these pathogens, and technology for designing and testing vectors for eventual use in recombinant protein production or in gene or drug delivery may be assigned to F14.

With F15 (Bioengineering and Imaging): Fellowship applications that are concerned primarily with bioengineering, bioimaging and technology development in support of the clinical and surgical sciences may be assigned to F15; fellowship applications that are concerned primarily with bioengineering, microscopic imaging and technology development in support of the basic and biological sciences may be assigned to F14.



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