NIH-CSR <script type="text/javascript"> var wmNotice = "UNT Web Archive - External links, forms, and search boxes may not function within this collection. Url: http://cms.csr.nih.gov/PeerReviewMeetings/CSRIRGDescription/AARRIRG/ACE.htm time: 14:56:31 Sep 20, 2008"; var wmHideNotice = "hide"; var contextRoot = "https://webarchive.library.unt.edu/eot2008/"; </script> <script type="text/javascript" src="https://webarchive.library.unt.edu/eot2008/js/disclaim.js"></script> <span id="Postingname3_PostingDisplayName">AIDS Clinical studies and Epidemiology Study Section [ACE] (Formerly AARR-6)</span> (AARRIRG)

[ACE Roster]

AIDS Clinical studies and Epidemiology [ACE] Study Section reviews studies of epidemiology, natural history, in vivo pathogenesis, and transmission of HIV infection in defined cohorts, and clinical studies/trials related to HIV/AIDS and associated opportunistic infections and cancers. This Study Section also reviews research related to nutrition and wasting, complementary and alternative medicine approaches, and clinical development of therapeutics, prophylactic agents, and biomedical interventions to treat or prevent HIV/AIDS and associated opportunistic infections and cancers. In addition, it addresses the development of diagnostics, clinical assays, and mathematical models.

Specific areas covered by ACE:

Population-based epidemiology and natural history of HIV infection, outcomes of anti-HIV chemotherapy, AIDS-associated opportunistic infections and cancers
In vivo pathogenesis of disease and progression in pediatric and adult populations
Multidisciplinary studies of epidemiology and/or medical interventions with biological and/or behavioral/psychological outcomes
Transmission [perinatal and adult] of infection in human populations/cohorts
Development, application, and evaluation of biological outcomes of interventions to prevent HIV infections and/or treat HIV disease
Clinical development of therapeutics for treatment and prophylaxis [including antivirals, immune restoration, gene-based therapies, opportunistic infections, AIDS- associated cancers, and neurological consequences]
Development of clinical diagnostics
Complementary and alternative therapies and non-behavioral interventions
Metabolic abnormalities and nutrition in HIV/AIDS
Pharmacological interaction, including HIV and other therapeutics, and substances of abuse and addiction
Development of biostatistical tools for epidemiological and cohort analysis and for clinical trials
Mathematical modeling of viral infection, transmission, and disease progression

ACE has the following shared interests within the AARR IRG:

Development of molecular or immunological assays for epidemiological studies are reviewed in AMCB or AIP, while population-based studies that address more traditional epidemiological questions are reviewed in ACE.
NAED has an emphasis on studies of neuropathology that impact on neuronal function at the tissue or cellular level; ACE addresses population-based epidemiology studies of nervous system dysfunction or drug abuse in AIDS.
Intervention studies that include primarily biomedical outcomes are reviewed in ACE; those studies that include primarily behavioral outcomes with standard virological/immunological measures are reviewed in BSPH and BSCH. Epidemiological studies of HIV infection and AIDS-defining illness are emphasized in ACE; epidemiological studies of HIV risk behaviors are emphasized in BSPH and BSCH.