[NAED Roster]

The NeuroAIDS and other End-organ Diseases [NAED] Study Section reviews applications on the effects of HIV infection and of AIDS on the nervous system and other organs and systems, and the actions of abused substances, their cognate ligands, and hormones on cellular immune processes. This includes neural-chemokine, neural-cytokine, neuroendocrine, and neuroimmune relationships and similar interactions in other organ systems. The pertinent areas of research also include modulation of the HIV, retroviral, and related diseases by drugs and other co-factors.

Specific areas covered by NAED:

• The NeuroAIDS and other End-organ Diseases [NAED] Study Section reviews applications on the effects of HIV infection and of AIDS on the nervous system and other organs and systems, and the actions of abused substances, their cognate ligands, and hormones on cellular immune processes. This includes neural-chemokine, neural-cytokine, neuroendocrine, and neuroimmune relationships and similar interactions in other organ systems. The pertinent areas of research also include modulation of the HIV, retroviral, and related diseases by drugs and other co-factors.
• Specific areas covered by NAED:
• Neurovirology, neuroimmunology, neuroendocrinology, behavioral immunology, and neuroimaging related to pathogenesis of HIV (and related viruses)
• Cell and molecular biology of HIV and glial-neuronal interactions
• Molecular and tissue-based studies of psychological effects of HIV disease
• Physiology and cell biology of cytokine-hormonal interactions in CNS and other organ systems
• Modulatory effects of pharmacological factors and their cognate ligands on neuroimmune systems and HIV infection
• Immunology, macrophage biology, endothelial cell biology, and pharmacology of drug abuse
• Studies of effects of used and abused substances and neuroactive drugs on establishment of infection, immunopathogenesis, neuropathogenesis, and disease progression
• Molecular and tissue-based studies HIV in non-lymphoid organ systems
• Studies of HIV-induced cardiomyopathy, renal disease, pulmonary dysfunction and other end-organ pathology

NAED has the following shared interests within the AARR IRG:

• AMCB emphasizes the regulation of viral and cellular biochemical processes, whereas NAED emphasizes the CNS-specific effects on virus regulation.
  
  
• AIP emphasizes the impact of the virus and the immune response in lymphoid systems, whereas NAED reviews applications that focus nervous system, and other end-organ diseases such as nephropathy and cardiomyopathy.
  
  
• NAED reviews studies of neuropathology that impact on neuronal function at the cellular level; ACE focuses on studies of clinical trials that may impact neuroAIDS and have neurological assessment as an outcome. Studies of cognitive dysfunction that affect behavior and adherence to therapy may be reviewed in BSCH.