NIH-CSR <script type="text/javascript"> var wmNotice = "UNT Web Archive - External links, forms, and search boxes may not function within this collection. Url: http://cms.csr.nih.gov/PeerReviewMeetings/CSRIRGDescription/GGGIRG/GCAT.htm time: 14:40:01 Sep 20, 2008"; var wmHideNotice = "hide"; var contextRoot = "https://webarchive.library.unt.edu/eot2008/"; </script> <script type="text/javascript" src="https://webarchive.library.unt.edu/eot2008/js/disclaim.js"></script> <span id="Postingname3_PostingDisplayName">Genomics, Computational Biology and Technology Study Section [GCAT]</span> (GGGIRG)

[GCAT Roster]

The Genomics, Computational Biology and Technology Study Section will consider research applications involving global and integrative analyses of biological systems, and the development of new computational and experimental methodologies. These would include (1) large-scale projects providing genetic information or resources, (2) functional and comparative genomics, (3) the application of bioinformatics and computational methods for collection, storage, integration, analysis, modeling and dissemination of genetic information, and (4) the development and validation of new experimental approaches applicable to systematic analyses. These projects may pertain to humans or model systems.

Specific areas covered by GCAT:

Large-scale genetic analyses (e.g., microarrays, genomics, genome sequencing, gene identification, and chemical genetics)
Large-scale genetic resources (e.g., collections of mutant strains and lines, tagged genes, and small molecule probes)
Comprehensive studies of specific systems (e.g., cell cycle, signal transduction, metabolic control, and disease pathways)
Technology application for understanding simple and complex systems (single gene/protein as well as high throughput approaches)
Computational and mathematical representation and simulation of genetic systems (e.g., genetic networks, signaling, physiology, and host-pathogen interactions)
Analysis, mining, and integration of genetic data, including the development of new algorithms and statistical genetic methods
Classification and annotation systems for genetic data
Data storage, databases, and access to genetic information (e.g., user interfaces)
Development of model organisms/systems for genetic, genomic, or high-throughput analyses

GCAT has the following shared interests within the GGG IRG:

In general the GCAT study section could review applications pertaining to new and emerging technologies, large-scale/high throughput studies, and computational modeling of genetic systems. Applications using established technologies applied to specific problems should be reviewed by other study sections.

With Molecular Genetics A, B, or C [MGA, MGB, or MGC]: Studies that apply high-throughput, computational, and/or mathematical modeling approaches to processes covered by the Molecular Genetics study sections could be assigned to MGA, MGB, or MGC as appropriate. Development of emerging high-throughput, computational, network modeling, or mathematical approaches may be more appropriate for assignment to GCAT.
With Genetic Variation and Evolution [GVE]: Large-scale studies of genetic variation and comparative genomics are shared interests. If studies are directed principally at understanding evolutionary processes or gene and genome evolution, including statistical methods, they could be assigned to GVE. If studies are directed principally at understanding such genetic or genomic questions as new and emerging genetic approaches, high throughput efforts, or computational modeling of genetic systems, they could be assigned to GCAT.
With Genetics of Health and Disease [GHD]: Genome scale studies applying workable technologies and approaches to human diseases may be appropriate for assignment to the GHD study section. Large-scale genomic and global studies may be appropriate for assignment to the GCAT study section.

GCAT has the following shared interests outside the GGG IRG:

With the Biological Chemistry & Macromolecular Biophysics [BCMB], Cell Biology [CB], Biology of Development & Aging [BDA], Oncological Sciences [ONC], Immunology [IMM], and Infectious Diseases & Microbiology [IDM] IRGs: Projects reviewed by GCAT may be pertinent to all areas of biology. For example, Biological Chemistry & Macromolecular Biophysics, Cell Biology and Biology of Development & Aging will cover topics related to the basic analysis of gene function, and other IRGs will cover aspects of genomics, proteomics, computational biology and technology related to specific organs and diseases. GCAT could review applications pertaining to new and emerging technologies, large-scale or high throughput studies, and computational modeling of genetic systems. Applications using established technologies applied to specific problems could be reviewed by other IRGs.

With the Bioengineering Sciences & Technologies [BST] IRG: Overlap is anticipated in the areas of statistical genetics, bioinformatics, and databases. If the focus is modeling technology or related analyses, bioinformatics or database technology, related computational analyses, or statistical methods for analyzing data, assignment to BST may be appropriate. If the focus is experimental, computational, or statistical investigation of questions related to genetics, regulation of gene expression, or genomics, assignment to GCAT may be appropriate.

With the Health of the Population [HOP] IRG: Applications with a primary focus on the genetic etiology of a disease could be reviewed by the GCAT study section. Applications with a primary focus on genetics as a risk factor in an epidemiologic study could be reviewed by HOP.

With the Organ-system/Disease IRGs - Hematology [HEME]; Cardiovascular Sciences [CVS]; Endocrinology, Metabolism, Nutrition, & Reproductive Sciences [EMNR]; Musculoskeletal, Oral, & Skin Sciences [MOSS]; Digestive Sciences [DIG]; Respiratory Sciences [RES]; and Renal & Urological Sciences [RUS]: Assignment of a gene/genomics/genetics application to an organ-system/disease IRG or to GCAT should be based on the nature of the scientific question(s) being addressed. Studies directed at a single organ-system or disease could be assigned to the organ system or disease IRG, even if basic approaches are used. Assignment could be to GCAT if the question(s) addressed may be applicable to multiple diseases or organ systems, or if the study involves an emerging approach for which expertise resides in GCAT.

With the Neuroscience IRGs - Molecular, Cellular & Developmental Neuroscience [MDCN]; Integrative, Functional, & Cognitive Neuroscience [IFCN]; and Brain Disorders & Clinical Neuroscience [BDCN]: Applications with a focus on large-scale gene/genomic/genetic studies could be reviewed by the GCAT study section. Applications with a focus on neuroscience processes could be reviewed by MDCN, IFCN, or BDCN.