NIH-CSR <script type="text/javascript"> var wmNotice = "UNT Web Archive - External links, forms, and search boxes may not function within this collection. Url: http://cms.csr.nih.gov/PeerReviewMeetings/CSRIRGDescription/CVSIRG/CVSEPS.htm time: 14:16:36 Sep 20, 2008"; var wmHideNotice = "hide"; var contextRoot = "https://webarchive.library.unt.edu/eot2008/"; </script> <script type="text/javascript" src="https://webarchive.library.unt.edu/eot2008/js/disclaim.js"></script> <span id="Postingname3_PostingDisplayName">Cardiovascular Sciences Small Business Activities [SBIR/STTR] Special Emphasis Panel [CVS Small Business SEP

Specific areas covered by the CVS Small Business SEP:

The Cardiovascular Sciences Small Business Activities Special Emphasis Panel [CVS (10)] will consider SBIR and STTR research applications that focus primarily on heart and circulatory system diagnostics, devices and therapies. Investigators may employ a range of approaches that include genetics, genomics and proteomics, molecular, cell, and computational biology, biochemistry, biophysics and bioengineering, imaging, analyses of model organisms, and human studies.

The CVS Small Business SEP has the following shared interests outside the CVS IRG:

With the Biology of Development and Aging [BDA] IRG: In general, applications studying the use of stem cell technology for cardiovascular specific issues could be assigned to the CVS Small Business SEP. BDA may be considered for more general developmental studies. Applications that use human embryonic stem cells might also be clustered in the BDA IRG, even if studying cardiovascular system specific issues.

With the Bioengineering Sciences and Technologies [BST] IRG: (1) Applications to develop fundamental bioengineering methods, pharmacologic and non-pharmacologic interventions, and computational/modeling approaches could be assigned to the BST IRG, whereas those proposing development and validation of methods focusing on evaluation of cardiac and vascular function could be assigned to the CVS Small Business SEP. (2) Proposals on bioengineering related specifically to devices, gene therapy, and computational modeling approaches for cardiovascular disease (stents, pacemakers, etc.) and their use in cardiovascular injury and repair may be assigned to the CVS Small Business SEP. Those involving more general aspects of devices (including materials and surfaces), gene therapy (including delivery systems), and computational modeling approaches could be assigned to the BST IRG.

With the Risk, Prevention, and Health Behavior [RPHB] IRG and the Health of the Population [HOP] IRG: Studies of behavior modification, including health education or training, directed toward the prevention and treatment of cardiovascular diseases, including psychological aspects, could be assigned to the RPHB IRG or to the HOP IRG, depending upon the level of analysis and the nature of the intervention. Applications focused on cardiovascular diseases, disorders, or functional consequences of behaviors could be assigned to the CVS Small Business SEP. Health education or training directed to the health care provider, not the patient, should also be assigned to the CVS Small Business SEP.

With the Hematology [HEME] IRG: Shared interest may exist concerning the use of common hematopoietic stem cell precursors. Assignment of applications that involve the transdifferentiation of cells between the blood and endothelial cell types would be resolved in the direction of the final phenotype, i.e., stem cell plasticity. For example, if the final phenotype of the differentiated tissue is a blood cell the application may be assigned to the HEME IRG. If the final phenotype of the differentiated tissue is a vascular smooth muscle cells then assignment to the CVS Small Business SEP may be appropriate.

With the Surgical Sciences, Biomedical Imaging and Bioengineering [SBIB] IRG: Applications to develop fundamental imaging methods or early stages of development of sensors may be assigned to the SBIB IRG, whereas those proposing development and validation of methods focusing on evaluation of cardiovascular function could be assigned to the CVS Small Business SEP. Proposals on bioengineering related specifically to devices for cardiovascular disease (stents, pacemakers, etc.) and their use in cardiovascular injury and repair are appropriate for the CVS Small Business SEP. Those involving more general aspects of device bioengineering could be assigned to the SBIB IRG.