[EBT Roster]

The EBT study section will consider applications (R01, R21, SBIR/STTR, etc.) focused on the development of new bioanalytical and biophysical tools, emerging techniques, and instruments.  The goal of these will be to probe the molecular aspects of biological systems.  Both hypothesis driven and non-hypothesis driven applications are expected.  Many of these applications will explore either novel technologies or improvements to existing techniques such as improved resolution, sensitivity, throughput, and the fundamental underpinnings of these techniques.

Specific areas covered by EBT include:

• Bioanalytical techniques such as sensors, separations, mass spectrometry, spectroscopy, arrays, microfluidics, and novel assays.
• Biophysical techniques such as magnetic resonance techniques; optical, electron and x-ray microscopy; x-ray and neutron techniques.
• Novel materials, reagents, and surface chemistries related to either bioanalytical or biophysical methods, including nanotechnology.
• Software development applied to bioanalytical instrumentation, instrumentation control, data reduction, data analysis, or data mining.
• The feasibility of recently introduced technologies to examine and explore biological systems (for example, proteomics, genomics, metabolomics, sequencing, screening, characterizing macromolecular interactions, or clinical applications) both in vivo and in vitro.

EBT has the following shared interests within the BCMB IRG:

• With Synthetic and Biological Chemistry A and B [SBCA and SBCB]: Combinatorial chemistry and novel materials are shared interests. If the focus is synthetic chemistry, then assignment could be to SBCA or SBCB. If the focus is analytical chemistry, then assignment could be to EBT.
  
  
• With Macromolecular Structure and Function C [MSFC]: Single molecule biophysics is a shared interest.  Applications for instrument or technique development in this area could be assigned to EBT.  Applications that use single molecule techniques to study biological systems could be assigned to MSFC.
  
  
• With Macromolecular Structure and Function A, B, & C (MSFA, MSFB, & MSFC): The development of biophysical techniques is a shared interest.  Applications focused on initial development could be assigned to EBT.  As the technique matures and as the biological applications become obvious, applications could be assigned to MSFA, MSFB, or MSFC.
  
  
• With Biochemistry and Biophysics of Membranes [BBM]:  Studies of methods development are a shared interest. Applications focused on development of methods with general applicability could be assigned to EBT. Applications focused on development of methods for membrane protein structure determination, including crystallization, could be assigned to BBM.

EBT has the following shared interests outside the BCMB IRG:

• With the Genes, Genomes, and Genetics [GGG] IRG:  The EBT study section shares interests with the GGG IRG in the area of tools for probing single nucleotide polymorphisms, arrays, and sequencing.  An application with focus on the development of new fundamental tools in these areas could be assigned to EBT. An application with focus on the genetic aspects of tool development could be assigned to the GGG IRG.
  
  
• With the Bioengineering Sciences and Technologies [BST] IRG: The EBT study section shares interests with the BST IRG in the development of new tools. Applications in this area that focus on chemistry or biophysics could be assigned to EBT. Applications in this area that focus on bioengineering or biomaterials could be assigned to the BST IRG.  Applications developing technologies for use in proteins are well suited for EBT and applications developing technologies aimed at nucleic acids are well suited for BST.
  
  
• With the Immunology [IMM]; Renal and Urological Sciences [RUS]; Molecular, Cellular, and Developmental Neuroscience [MDCN]; Integrative, Functional, and Cognitive Neuroscience [IFCN]; and the Brain Disorders and Clinical Neuroscience [BDCN] IRGs: EBT shares interests with all of these IRGs in developing new tools and techniques.  An application with emphasis on the development of a new tool or technique at the chemical or biophysical level (such as biomarkers) could be assigned to EBT. An application that uses such tools but with emphasis on the organ or disease could be assigned to appropriate organ or disease IRG.