Biological Chemistry and Macromolecular Biophysics Small Business Activities [SBIR/STTR] Special Emphasis Panels

[BCMB Small Business SEPs]

The BCMB IRG reviews SBIR/STTR applications within the areas covered by its regular study sections in two small business panels.

Bioanalytical Chemistry, Chemistry and Biophysics SBIR/STTR 

[BACB SBIR/STTR: BCMB (10)]

The BACB SBIR/STTR Special Emphasis Panel reviews SBIR/STTR applications in the general area of bioanalytical chemistry, chemistry and biophysics.

Specific areas covered by the BACB SBIR/STTR SEP include:

  • Bioanalytical techniques such as mass spectrometry, sensors, separations, spectroscopy, arrays, microfluidics, and novel assays
  • Nanotechnology
  • Novel materials, reagents, and surface chemistries related to either bioanalytical or biophysical methods
  • Development of instrumentation and systems for proteomics and protein analysis
  • Biophysical techniques such as magnetic resonance techniques; optical, electron and x-ray microscopy; x-ray and neutron diffraction techniques
  • Agents for bioremediation
  • Structural biology, especially protein structure and interactions

The BACB SBIR/STTR SEP has the following shared interests within the BCMB IRG:

  • With the Drug Discovery and Development SBIR/STTR SEP [BCMB 11]:  The BACB SBIR/STTR SEP shares interest in protein chemistry with the DDD SBIR/STTR SEP.  If the emphasis is on the development of platforms, systems or methods for analysis, BACB SBIR/STTR may be more appropriate.  If the emphasis is toward development of a therapeutic compound, the DDD SBIR/STTR SEP may be more appropriate.

The BACB SBIR/STTR SEP has the following shared interests outside of the BCMB IRG:

  • With the Bioengineering Sciences and Technologies [BST] IRG: The BACB SBIR/STTR SEP shares interests with the BST IRG in the development of new tools and instrumentation.  Small business applications in this area that focus on instrumentation and tools using bioanalytical, chemical or biophysical approaches may be assigned to the BACB SBIR/STTR SEP. Applications in this area that focus on instrumentation and tools using bioengineering and biomaterials approaches could be assigned to the BST IRG.

  • With the Biology of Development and Aging [BDA]; Immunology [IMM]; Infectious Diseases and Microbiology [IDM]; AIDS and Related Research [AARR]; Oncological Sciences [ONC]; Hematology [HEME]; Cardiovascular Sciences [CVS]; Endocrinology, Metabolism, Nutrition, and Reproductive Sciences [EMNR]; Musculoskeletal, Oral and Skin Sciences [MOSS], Digestive Sciences [DIG], Respiratory Sciences [RES], Renal and Urological Sciences [RUS], and the Molecular, Cellular, and Developmental Neuroscience [MDCN] IRGs: The BACB SBIR/STTR SEP shares interests with disease and organ based IRGs in the development of use of new tools and instrumentation. Small business applications that focus on instrumentation and tools using bioanalytical, chemical or biophysical approaches may be assigned to the BACB SBIR/STTR SEP. Applications that focus on applying these tools to a disease or organ specific issue may be assigned to the relevant organ or disease IRG.

Drug Discovery and Development SBIR/STTR 

[DDD SBIR/STTR: BCMB (11)]

This Special Emphasis Panel reviews SBIR/STTR applications in small molecule drug discovery and development, medicinal chemistry, pharmaceutical chemistry, protein based therapeutics, and protein chemistry.  The focus is on development of therapeutics.

Specific areas covered by the DDD SBIR/STTR SEP include:

  • Medicinal chemistry
  • Synthetic chemistry
  • Combinatorial chemistry
  • Natural Product chemistry
  • Pharmaceutical chemistry
  • Computational drug design
  • Protein therapeutics
  • Protein chemistry and engineering
  • Purification and biochemical analysis of proteins

The DDD SBIR/STTR SEP has the following shared interests within the BCMB IRG:

With the Bioanalytical Chemistry, Chemistry and Biophysics SBIR/STTR SEP [BCMB 10]:  The DDD SBIR/STTR SEP shares interest in protein chemistry with the BACB SBIR/STTR SEP.  If the emphasis is on the development of platforms, systems or methods for analysis, the BACB SBIR/STTR SEP may be more appropriate.  If the emphasis is toward development of a therapeutic compound, the DDD SBIR/STTR SEP may be more appropriate.

The DDD SBIR/STTR SEP has the following shared interests outside of the BCMB IRG:

  • With the Bioengineering Sciences and Technologies [BST] IRG: The DDD SBIR/STTR SEP shares interests with the BST IRG in drug development and delivery. Small business applications that focus on the synthesis or chemistry of drugs and delivery systems may be referred to the DDD SBIR/STTR SEP. Small business applications that focus on the bioengineering of drugs and delivery systems may be referred to the BST IRG.

     
  • With the Biology of Development and Aging [BDA]; Immunology [IMM]; Infectious Diseases and Microbiology [IDM]; AIDS and Related Research [AARR]; Oncological Sciences [ONC]; Hematology [HEME]; Cardiovascular Sciences [CVS]; Endocrinology, Metabolism, Nutrition, and Reproductive Sciences [EMNR]; Musculoskeletal, Oral and Skin Sciences [MOSS], Digestive Sciences [DIG], Respiratory Sciences [RES], Renal and Urological Sciences [RUS], and the Molecular, Cellular, and Developmental Neuroscience [MDCN] IRGs: The DDD SBIR/STTR SEP shares interests with disease and organ based IRGs in drug development and delivery.  SBIR/STTR applications with a focus on basic questions of structure determination or early drug discovery (hit to lead and lead optimization) or containing a substantial synthetic component may be assigned to the DDD SBIR/STTR SEP.  Applications on the clinical evaluation of a drug candidate may be assigned to the relevant organ or disease IRG.


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