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    Posted: 03/16/2007    Updated: 03/21/2008
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Lapatinib Ditosylate

This page contains brief information about lapatinib ditosylate and a collection of links to more information from the National Cancer Institute (NCI), the Food and Drug Administration (FDA), and the National Library of Medicine (NLM).

US Brand Name(s):Tykerb
FDA Approved:Yes

Lapatinib ditosylate is approved by the Food and Drug Administration (FDA) to be used with other drugs to treat advanced or metastatic breast cancer. It is used in patients whose cancer is HER2 positive and who have already been treated with other drugs.

Lapatinib ditosylate is also being studied in the treatment of other types of cancer.

Information from the FDA

FDA Approval for Lapatinib Ditosylate - Information from the FDA about the approval of this drug and the clinical trials that led to the approval.

Information from the NCI

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

The ALTTO (Adjuvant Lapatinib and/or Trastuzumab Treatment Optimisation) Breast Cancer Trial (03/12/2008) - Information about a major NCI-supported clinical trial for this drug.

Clinical Trial Results: Lapatinib Plus Capecitabine Delays Progression of HER2-Positive Breast Cancer (06/03/2006) - Important clinical trial results for this drug, background information, and how the trial was done.

Information from the NLM

MedlinePlus Information on Lapatinib Ditosylate - A lay language summary of important information about this drug that may include the following:

  • warnings about this drug,
  • what this drug is used for and how it is used,
  • what you should tell your doctor before using this drug,
  • what you should know about this drug before using it,
  • other drugs that may interact with this drug, and
  • possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This NLM patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Clinical Trials

Clinical Trials for Lapatinib Ditosylate - Check for trials from NCI's PDQ Cancer Clinical Trials Registry now accepting patients.

Important: The drug information on this Web page is meant to be educational. It is not a substitute for medical advice. The information may not cover all possible uses, actions, interactions, or side effects of this drug, or precautions to be taken while using it. Please see your health care professional for more information about your specific medical condition and the use of this drug.


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