The MCH SAMMEC program derives
smoking-attributable mortality (SAM) using an attributable-fraction
formula (Lilienfeld and Lilienfeld,
1980) originally described by Levin
(1953). The smoking attributable fractions (SAFs) of infant
death for four perinatal conditions are calculated using maternal
smoking prevalence and relative risk (RR) of death for infants
of maternal smokers relative to infants of maternal nonsmokers.
SAFs for each disease and sex are derived using the following
formula:
SAF = [p0 + p1(RR1) - 1] / p0 + p1(RR1)
- p0 is the percentage of current maternal nonsmokers in the study group
- p1 is the percentage of current maternal smokers in the study group
- RR1 is the relative risk of death for infants of current
maternal smokers compared with the risk of death for infants
of current maternal nonsmokers
National maternal smoking estimates used by MCH SAMMEC for
1999 to 2004 were obtained from Vital Statistics from the
National Center for Health Statistics (NCHS), with some exceptions.
California does not report smoking during pregnancy on the
birth certificate, and prevalence estimates were derived from
the California Maternal and Infant Health Assessment (MIHA)
for the entire time frame. For 1999, Indiana, New York State,
and South Dakota maternal smoking estimates were obtained
from the Behavioral Risk Factor Surveillance System (BRFSS).
MCH SAMMEC uses RR estimates for short gestation/low birth weight, Sudden Infant Death Syndrome (SIDS), Respiratory Distress (Syndrome) - newborn (RDS), and other infant conditions of the newborn obtained from a meta analysis of the epidemiological literature conducted by Gavin et al. (2001).
MCH SAMMEC applies the SAF to infant mortality data derived
from CDC's WONDER mortality records maintained on the Web
at http://wonder.cdc.gov/.
MCH SAMMEC use the following formula to calculate SAM:
SAM = Number of deaths x SAF
MCH SAMMEC multiplies the number of smoking-attributable deaths by the remaining life expectancy (RLE) at birth for each sex to estimate YPLL.
Smoking-attributable YPLL = SAM x RLE
Life expectancy data for the nation were obtained from NCHS.
YPLL can also be calculated using a fixed life expectancy
estimate, such as age 75, and can use data for different study
populations. Total YPLL estimates are generated for each infant
condition by sex and both sexes combined. |