Jane E. Lamerdin, Karolyn Burkhart-Schultz, Linda Danganan, Laurie Gordon, Stephanie Stilwagen, Glenda Quan, Hoan Phan, Nelson Velasco, Andre Arellano, Brent Kronmiller, Long Do, Astrid Terry, Warren Regala, Vijay Viswanathan, Jennifer Dias, Amy Brower, Tim Andriese, Pat Poundstone, Julie Avila, Jackie Coefield, Susan Lucas, Tina Attix, Stephenie Liu, Robert Bruce, Evan Skowronski, Rick Colyaco, Arthur Kobayashi, David Ow, Matt Nolan, Anthony V. Carrano, Anne. S. Olsen, and Paula McCready 
Joint Genome Institute, Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, Livermore, CA 94550 
lamerdin1@llnl.gov 

2. Genomic Sequencing of 3 Mb of Human Chromosome 16p13.3 Containing 4 Disease Genes 

M.O. Mundt, D.O. Ricke, D.C. Bruce, A.C. Munk, D.L. Robinson, M.D. Jones, J.M. Buckingham, L.A. Chasteen, E.H. Saunders, L.S. Thompson, L.A. Goodwin, A.L. Williams, J.L. Longmire, P.S. White, L.L. Deaven, and N.A. Doggett 
Joint Genome Institute, Center for Human Genome Studies, Los Alamos National Laboratory, Los Alamos, NM 87545 
doggett@lanl.gov 

3. Sequencing Human Chromosome 14 and the Mouse Major Histocompatibility Locus: A Progress Report 

Lee Rowen, Anup Madan, Shizhen Qin, Lee Hood, and the Multimegabase Sequencing Group Department of Molecular Biotechnology, University of Washington, Seattle, Washington 
leerowen@u.washington.edu 

4. Physical Mapping and Sequencing of Human Chromosome 16p12.1-11.2 

Hyung Lyun Kang, Yicheng Cao, So Hee Dho¹, Diana Bocskai, Mei Wang, Xuequn Xu, Jun-Ryul Huh¹, Byeong-Jae Lee¹, Francis Kalush², Judith G. Tesmer³, Eunpyo Moon⁴, Norman A. Doggett³, Mark D. Adams², Melvin I. Simon, and Ung-Jin Kim 
Division of Biology, Caltech, Pasadena, CA 91125 
¹ Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Korea; ² The Institute for Genomic Research, Rockville, Maryland; ³ Los Alamos National Laboratory, Los Alamos, New Mexico; and ⁴ Ajou University, Suwon, Korea 
simonm@cco.caltech.edu 

5. Human Telomere Mapping and Sequencing 

Han-Chang Chi¹, Deborah L. Grady¹, Harold C. Riethman², and Robert K. Moyzis^1 
1Department of Biological Chemistry, College of Medicine, University of California at Irvine, Irvine, CA 92697 and ²The Wistar Institute, Philadelphia, PA 19104 
hcchi@uci.edu 

6. A Comparison of Sequence Gap Closure Strategies 

Glenda G. Quan, Karolyn Burkhart-Shultz, Timothy Andriese, Andre Arellano, Long Do, Arthur Kobayashi, Brent Kronmiller, Madison Macht, Matt Nolan, David Ow, Hoan Phan, Melissa Ramirez, Warren Regala, Christina Sanders, Stephanie Stilwagen, Astrid Terry, Nelson Velasco, Vijay Viswanathan, Anthony V. Carrano, and Jane E. Lamerdin 
Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA 94550 
quan1@llnl.gov 

Matt P. Nolan, Jane E. Lamerdin, Glenda G. Quan, and Anthony V. Carrano 
Joint Genome Institute, Lawrence Livermore National Laboratory, Livermore, California 
nolan1@llnl.gov 

8. Process Description of a 5 Mb / Year Finish Sequencing Operation Using 100% Plasmid Double End Sequencing 

David C. Bruce, Leslie A. Chasteen, Donna L. Robinson, Myrona D. Jones, Jennifer Bryant, Nancy C. Brown, Beverly Parson-Quintana, Darrell O. Ricke, Mark O. Mundt, P. Scott White, Norman Doggett, and Larry L. Deaven 
Human Genome Center, Los Alamos National Laboratory, Mail Stop M888, Los Alamos, NM 87545 
bruce@telomere.lanl.gov 

9. Automation of Finishing at JGI-LLNL 

Stephanie Stilwagen, Matt Nolan, Andre Arellano, Karolyn Burkhart-Schultz, Long Do, Arthur Kobyashi, Brent Kronmiller, Madison Macht, David Ow, Hoan Phan, Glenda Quan, Melissa Ramirez, Warren Regala, Christina Sanders, Astrid Terry, Stephan Trong, Nelson Velasco, Vijay Viswanathan, Anthony Carrano, and Jane Lamerdin 
Joint Genome Institute, Lawrence Livermore National Laboratory, 7000 East Ave, L-452, Livermore CA 94550 
stilwagen1@llnl.gov 

10. Sequence Validation and Quality Assessment at the Joint Genome Institute 

M. Bussod, N. Doggett, J. Fawcett, D. Ricke, K. Watson, O. Tatum, P.S. White, and M. Mundt 
Center for Human Genome Studies, Los Alamos National Laboratory, Los Alamos, NM 87545 
mira@telomere.lanl.gov 

11. LANL Finishing Team Accomplishments in FY98 

J. Buckingham, L. Goodwin, C. Munk, L. Saunders, S. Thompson, S. Ueng, D. Ricke, and M. Mundt 
Joint Genome Institute, Center for Human Genome Studies, Los Alamos National Laboratory, Los Alamos, NM 87545 
buck@telomere.lanl.gov 

12. JGI-LANL Sequencing Cost Reduction and Quality Improvement: R&D Results 

Owatha L. "Tootie" Tatum and P. Scott White 
Los Alamos National Laboratory, Los Alamos, New Mexico 
tootie@telomere.lanl.gov 

13. Concatenation cDNA Sequencing and Analysis of 500 Human Brain cDNA Clones 

Wei Yu, John Bouck, James H. Gorrell, Donna M. Muzny, and Richard A. Gibbs 
Human Genome Sequencing Center, Department of Molecular and Human Genetics Baylor College of Medicine, Houston, Texas 77030 
agibbs@bcm.tmc.edu 

14. Cosmid Finishing and Full Insert cDNA Sequencing Using Differential Extension with Nucleotide Subsets (DENS) 

D. Zevin-Sonkin^1,2, H. Hovhanissyan¹, A. Ghochikyan¹, L. Lvovsky¹, A. Liberzon¹, M.C. Raja^1,3, E. Ben-Asher², G. Glusman², D. Lancet², and L.E. Ulanovsky^1,3 
1Dept. of Structural Biology and ²Dept. of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, ISRAEL; ³CMB, Argonne National Laboratory, Argonne, IL 60439-4833 
levy@anl.gov 

Nobuo Nomura, Takahiro Nagase, Ken-ichi Ishikawa, Reiko Kikuno, Mikita Suyama, Nobuyuki Miyajima, Ayako Tanaka, Hirokazu Kotani, and Osamu Ohara. 
Kazusa DNA Research Institute, Kisarazu, Chiba 292-0812 Japan 
nomura@kazusa.or.jp