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Human
Genome News Archive Edition |
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Sponsored
by the U.S. Department of
Energy Human Genome Program
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Human Genome News, January-June 1997; 8:(3-4)
Researchers at the National Center for Biotechnology Information (NCBI) used known DNA sequences of 70 human genes linked to such disorders as colon cancer and obesity to search public sequence databases for counterparts in yeast, bacteria, and roundworm. They found the highest number of matches in worm databases (36%) and expect to find more as the other half of the worm’s genes are sequenced. Another 10% to 20% of the human genes had counterparts inbacteria and yeast. New functions were predicted for a number of disease genes. A paper reporting this work by Eugene Koonin and colleagues (NCBI) is published in Proc. Natl. Acad. Sci. USA 94, 5831-36 (May 1997).
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