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The year 2003 marked two major milestones in genomics:

• Completion of the sequencing of the human genome
• 50th anniversary of the discovery of the DNA double helix

To mark these milestones, events took place around the world. Several retrospective articles and compilations were also written.

Press Conference Marking Completion of the Human Genome Project April 14, 2003

• Press Release: International Consortium Completes Human Genome Project, Bethesda, Maryland, April 14, 2003

• DOE's Celebration of the Genome - Statement of Secretary Spencer Abraham

• Welcoming Remarks by Raymond L. Orbach

Papers from Science and Nature

• Special issue of Nature: DNA 50th anniversary: Double helix at 50 (April 24, 2003)
  • "A Vision for the Future of Genomics Research," Francis S. Collins, Eric D. Green, Alan E. Guttmacher, Mark S. Guyer, Nature Apr 24: 835 (2003)
  • "Genetics and the Making of Homo sapiens," Sean B. Carroll, Nature Apr 24: 849 (2003)
  • "Genome Sequencing: Revelations from a Bread Mould," Jonathan Arnold, Nelson Hilton, Nature Apr 24: 821 (2003)
• Office of Science Overview
• Special issue of Science: Building on the DNA Revolution (April 11, 2003)
  • "The Human Genome Project: Lessons from Large-Scale Biology," Francis S. Collins, Michael Morgan, Aristides Patrinos, Science 300, 286 (2003)
  • "Realizing the Potential of the Genome Revolution: The Genomes to Life Program," Marvin E. Frazier, Gary M. Johnson, David G. Thomassen, Carl E. Oliver, Aristides Patrinos, Science 300, 290 (2003)

April 2003 Scientific Symposium: From Double Helix to Human Sequence - and Beyond

• Symposium Information
• Webcast Information

Images

• Ari Patrinos. Credit: U.S. Department of Energy Human Genome Program (print quality, 759 kb)
• Francis Collins. Credit: National Human Genome Research Institute (Maggie Bartlett) (print quality, 1757 kb)
• Image Gallery (free, reproducible, high resolution)

Resources

• HGP Timeline
• Primer: Genomics and Its Impact on Science and Society
• The Human Genome and Beyond

Events and Celebrations

From Double Helix to Human Sequence - and Beyond!
Natcher Auditorium, Rockville, MD April 14th and 15th, 2003
A two day scientific symposium where more than 35 participants will discuss the science and history of the Human Genome Project.

Bringing the Genome to You
Smithsonian Institution's National Museum of Natural History, Washington, D.C., April 15th, 2003
A half-day public symposium on how genomics influences health and society.

National DNA Day
April 25th, 2003
Coordinated among classrooms around the country. Plan a teachable moment.

University of Cambridge Genome Celebration

Websites and Retrospectives

Time: The Secret of Life (Feb. 17, 2003)

NY Times: A Revolution at 50 (Feb. 25, 2003)

Physics Today: Rosalind Franklin and the Double Helix, Mar. 2003

NPR Talk of the Nation: DNA Structure Anniversary Feb. 28, 2003

NPR All Things Considered: Commentary on DNA, Feb. 28, 2003

NPR All Things Considered: Discovering the Double Helix: A 50-Year Anniversary, Feb. 28, 2003

NY Newsday: The Double Helix--50 Years Later (Feb., 2003)

Boston Museum of Science DNA 50

Cold Spring Harbor Laboratory 50th Anniversary of DNA Double Helix

Genome Canada

Linus Pauling and the Race for DNA (Oregon State University website)

Important Papers from the Journals

• Office of Science Overview
• Special issue of Science: Building on the DNA Revolution (April 11, 2003)
  • "The Human Genome Project: Lessons from Large-Scale Biology," Francis S. Collins, Michael Morgan, Aristides Patrinos, Science 300, 286 (2003)
  • "Realizing the Potential of the Genome Revolution: The Genomes to Life Program," Marvin E. Frazier, Gary M. Johnson, David G. Thomassen, Carl E. Oliver, Aristides Patrinos, Science 300, 290 (2003)
• Special issue of Nature: DNA 50th anniversary: Double helix at 50 (April 24, 2003)
  • "A Vision for the Future of Genomics Research," Francis S. Collins, Eric D. Green, Alan E. Guttmacher, Mark S. Guyer, Nature Apr 24: 835 (2003)
  • "Genetics and the Making of Homo sapiens," Sean B. Carroll, Nature Apr 24: 849 (2003)
  • "Genome Sequencing: Revelations from a Bread Mould," Jonathan Arnold, Nelson Hilton, Nature Apr 24: 821 (2003)

Nature Genetics: A 10-Year Retrospective 1992-2002 (vol. 33, March 2003)

Scientific American Rosalind Franklin and the Double Helix, April 2003 issue

Nature Molecular Structure of Nucleic Acids, Watson, J. D. & Crick, F. H. C., 171, 737-738 (1953)

Nature Genome Gateway

Science Functional Genomics Gateway

Guide to the February 2001 Nature and Science papers on the Human Genome Draft Sequence

Publications Summarizing Various Aspects of the Human Genome Project

• Controversial From the Start --Science article summarizing the history of the HGP (February 2001)
• Genomes: 15 Years Later--A perspective from Charles DeLisi, HGP Pioneer (July 2001)
• Origins of the Human Genome Project by Robert Cook-Deegan (1994; Risk Journal)
• History of the DOE Human Genome Program from the U.S. DOE Office of Science, Office of Biological and Environmental Research, Biological and Environmental Research Program.
• What is the Human Genome Project?: A Summary of the Project Beginnings (published April 1990)
• Report on the Human Genome Initiative for the Office of Health and Environmental Research: April 1987 report that officially outlined the Department of Energy's strategies for the Human Genome Project
• "The Alta Summit, December 1984," by Robert Cook-Deegan, Genomics 5, 661-663 (October 1989): The beginning of the Human Genome Project.

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