Coetano Neto S, Della Negra M, Queiroz W, Lian YC, Amancio O, Braga JP, Fisberg M; International Conference on AIDS.
Int Conf AIDS. 1994 Aug 7-12; 10: 221 (abstract no. PB0899).
Inst. Infect. Emilio Ribas, Sao Paulo, Brazil.
OBJETIVES: We measured micronutrients (zinc, copper) values in pediatrics patients with AIDS (P2-CDC) to determine whether micronutrient deficiencies were associated with the wasting syndrome (CDC). METHODS: Serum from 31 children (8 months--5 years) patients was evaluated for concentration of zinc and copper (atomic absortion spectrophotometry). Comparisons were made, in this group, between children with wasting sindrome and children with non-wasting status. The control group was based in 23 children HIV negative and eutrophics from the same environment. RESULTS: With application of Waterlow criteria (weight/height), we obtained 18 (59%) children with wasting status (W) and 13 (41%) with non-wasting status (NW). Mean serum levels for zinc were 107.22 mcg/dl in group W and 125.28 mcg/dl in group NW. Copper levels were 160.55 mcg/dl (group W) and 170.76 mcg/dl (group NW). Group control the results were: zinc = 108.70 mcg/dl and copper = 142.17 mcg/dl. DISCUSSION AND CONCLUSIONS: Decreased micronutrients concentrations are common in adults HIV infected patients. In HIV positive children, we didn't find statistics differences for copper between two groups (W and NW) (p = 0.1). Levels for zinc were significantly lower in group with wasting status (p = 0.01). Comparisons between group seronegative and group with AIDS, didn't show statistics differences for zinc (p = 0.4) and copper (p = 0.06) values. Study must be continued to conclude about the relantionship of micronutrients, nutritional status and children with HIV infection.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Adult
- CD4 Lymphocyte Count
- Child
- Copper
- HIV
- HIV Infections
- HIV Seropositivity
- HIV Wasting Syndrome
- Hematologic Tests
- Humans
- Malnutrition
- Micronutrients
- Nutritional Status
- Trace Elements
- Zinc
- Zinc Compounds
- organization & administration
Other ID:
UI: 102210365
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