Jingu M, Assina Y, Musungay L, Ngwala P, Mbuyi K, Mbu L; International Conference on AIDS.
Int Conf AIDS. 1993 Jun 6-11; 9: 648 (abstract no. PO-C02-2586).
OBJECTIVE: To identify behavior and biologic factors associated with HIV-1 infection in married couples. METHODS: 12,000 employees and their spouses were screened for HIV-1 and interviewed past and current behaviors and sexual practices. RESULTS: Of 316 couples with one or more HIV+ partners, 68 couples (21%) were concordantly HIV+ (M+F+) and 248 couples (78%) were HIV discordant. Concordant HIV-1 infection within couples was associated with symptomatic HIV disease in one of the HIV- infected partners and with genital ulcers in either partner. However, in this study neither of these two risk factors could be reliably differentiated from the correlated effect of a presumptively longer duration of sexual contact with the partner who was first infected by HIV. Among those women married to HIV+ men, an increased risk of HIV infection was associated with putting foreign substances in the vagina; conversely, among women married to HIV+ men, a decreased prevalence of HIV infection observed in those who regularly practiced vaginal irrigation with water. Among men married to HIV+ women, a trend toward elevated risk of HIV infection was associated with sexual intercourse during menses. CONCLUSION: A number of sexual behaviors and other risk factors identified in this study (such as ulcers) provide opportunities for intervention against heterosexual transmission of HIV-1 in Zaire. These factors are currently being evaluated prospectively in this same group of couples.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Case-Control Studies
- Democratic Republic of the Congo
- Disease Transmission, Horizontal
- Female
- HIV
- HIV Infections
- HIV Seropositivity
- HIV-1
- Humans
- Male
- Prevalence
- Risk Factors
- Sexual Behavior
- transmission
Other ID:
UI: 102205888
From Meeting Abstracts